{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T13:57:21Z","timestamp":1776434241583,"version":"3.51.2"},"reference-count":21,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,12,8]],"date-time":"2014-12-08T00:00:00Z","timestamp":1417996800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Yeungnam University Medical Center"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["LUTS"],"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Because it is well known that the prostate volume is not directly associated with the degrees of lower urinary tract symptom (<jats:styled-content style=\"fixed-case\">LUTS<\/jats:styled-content>), we hypothesized that change of the prostatic urethra led by prostatic enlargement as missing links between them. To provide an integral description, we determined the ratio between prostate volume and prostatic urethral length (<jats:styled-content style=\"fixed-case\">RPVL<\/jats:styled-content>), and investigated its clinical implication.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Prostate volume, prostatic urethral length, <jats:styled-content style=\"fixed-case\">RPVL<\/jats:styled-content> was measured from transrectal ultrasonography for 213 consecutive patients. The degree of <jats:styled-content style=\"fixed-case\">LUTS<\/jats:styled-content> was investigated using the international prostate symptom score (<jats:styled-content style=\"fixed-case\">IPSS<\/jats:styled-content>) and uroflowmetry, then the correlations were analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>While no variables were significantly linked with total <jats:styled-content style=\"fixed-case\">IPSS<\/jats:styled-content>, obstructive symptoms (<jats:styled-content style=\"fixed-case\">IPSS Q247<\/jats:styled-content>) showed a negative association (r = \u22120.3, <jats:italic>P &lt;<\/jats:italic> 0.001) and irritative symptoms (<jats:styled-content style=\"fixed-case\">IPSS Q1356<\/jats:styled-content>) showed a positive association solely with <jats:styled-content style=\"fixed-case\">RPVL<\/jats:styled-content> (r = 0.186, <jats:italic>P =<\/jats:italic> 0.007). These relevancies were enhanced (r = \u22120.471 [<jats:italic>P =<\/jats:italic> &lt;0.001] and 0.3 [<jats:italic>P =<\/jats:italic> 0.004], respectively) in patients with a larger prostate (over 30 g, <jats:italic>n<\/jats:italic> = 93), but disappeared in their smaller counterparts (below 30 g, <jats:italic>n<\/jats:italic> = 120), (r = \u22120.133 [<jats:italic>P =<\/jats:italic> 0.143] and 0.75 [<jats:italic>P =<\/jats:italic> 0.410], respectively). In uroflowmetry, prostate urethral length showed positive correlation (r = 0.319 [<jats:italic>P &lt;<\/jats:italic> 0.001]), and <jats:styled-content style=\"fixed-case\">RPVL<\/jats:styled-content> showed negative correlation (r = \u22120.195 [<jats:italic>P =<\/jats:italic> 0.004]) with post voiding residual amount, but these relationships similarly vanished in men with a smaller prostate.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The structural variation of the prostatic urethra within the prostate reflected by <jats:styled-content style=\"fixed-case\">RPVL<\/jats:styled-content> showed correlation with the degree of <jats:styled-content style=\"fixed-case\">LUTS<\/jats:styled-content>, with a tendency toward increasing prostatic urethra in obstructive and decreasing prostatic urethra in irritative symptoms, in men with a relatively large prostate.<\/jats:p><\/jats:sec>","DOI":"10.1111\/luts.12083","type":"journal-article","created":{"date-parts":[[2014,12,9]],"date-time":"2014-12-09T11:15:21Z","timestamp":1418123721000},"page":"113-119","source":"Crossref","is-referenced-by-count":9,"title":["Structural Variation of Prostate Urethra Reflected by the Ratio Between Prostate Volume and Prostatic Urethral Length is Associated with the Degrees of Lower Urinary Tract Symptoms"],"prefix":"10.1111","volume":"8","author":[{"given":"Young Hwii","family":"KO","sequence":"first","affiliation":[{"name":"Department of Urology College of Medicine, Yeungnam University  Daegu Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Phil Hyun","family":"SONG","sequence":"additional","affiliation":[{"name":"Department of Urology College of Medicine, Yeungnam University  Daegu 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