{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T23:28:40Z","timestamp":1773012520182,"version":"3.50.1"},"reference-count":35,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,11,30]],"date-time":"2015-11-30T00:00:00Z","timestamp":1448841600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Coloplast Japan"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["LUTS"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate the cost effectiveness of disposable, hydrophilic\u2010coated catheters in Japan.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A Markov decision model previously applied in a European study was used to evaluate the cost effectiveness of intermittent self\u2010catheterization (<jats:styled-content style=\"fixed-case\">ISC<\/jats:styled-content>) with hydrophilic\u2010coated catheters in Japanese spinal cord injury (<jats:styled-content style=\"fixed-case\">SCI<\/jats:styled-content>) patients suffering from chronic urinary retention from a lifetime perspective. To adjust the model to a Japanese setting, relevant Japanese data regarding the baseline risk of urinary tract infection (<jats:styled-content style=\"fixed-case\">UTI<\/jats:styled-content>), the average age at onset of <jats:styled-content style=\"fixed-case\">SCI<\/jats:styled-content>, costs, and general mortality were extracted from published literature, national statistics, or the opinions of Japanese experts. The direct medical costs, quality\u2010adjusted life years (<jats:styled-content style=\"fixed-case\">QALYs<\/jats:styled-content>) and life years gained (<jats:styled-content style=\"fixed-case\">LYG<\/jats:styled-content>) were calculated from the payers' perspective. An annual discount rate of 2% was applied to both the costs and the effects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The incremental cost of hydrophilic\u2010coated catheters was 1 279 886 yen (<jats:styled-content style=\"fixed-case\">US<\/jats:styled-content>$ 10 578 at an exchange rate of <jats:styled-content style=\"fixed-case\">US<\/jats:styled-content>$ 1 = 121 yen) per <jats:styled-content style=\"fixed-case\">SCI<\/jats:styled-content> patient, but they yielded an additional 0.334 <jats:styled-content style=\"fixed-case\">QALYs<\/jats:styled-content> and 0.781 <jats:styled-content style=\"fixed-case\">LYG<\/jats:styled-content> compared with uncoated catheters. The incremental cost\u2010effectiveness ratio (<jats:styled-content style=\"fixed-case\">ICER<\/jats:styled-content>) of hydrophilic\u2010coated catheters vs. uncoated catheters was 3 826 351 yen\/<jats:styled-content style=\"fixed-case\">QALY<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">US<\/jats:styled-content>$ 31 623\/<jats:styled-content style=\"fixed-case\">QALY<\/jats:styled-content>) gained and 1 639 562 yen\/<jats:styled-content style=\"fixed-case\">LYG<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">US<\/jats:styled-content>$ 13 550\/<jats:styled-content style=\"fixed-case\">LYG<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">ICER<\/jats:styled-content> of 3.8 million yen (<jats:styled-content style=\"fixed-case\">US<\/jats:styled-content>$ 31 405) falls well within the Japanese societal willingness to pay per <jats:styled-content style=\"fixed-case\">QALY<\/jats:styled-content> gained; therefore, hydrophilic\u2010coated catheters can be considered highly cost\u2010effective in Japan compared with uncoated catheters. However, because of the lack of relevant studies, a number of key parameters could not be based on Japanese data, and further research among people with <jats:styled-content style=\"fixed-case\">SCI<\/jats:styled-content> in Japan is recommended.<\/jats:p><\/jats:sec>","DOI":"10.1111\/luts.12122","type":"journal-article","created":{"date-parts":[[2015,11,30]],"date-time":"2015-11-30T11:14:41Z","timestamp":1448882081000},"page":"142-150","source":"Crossref","is-referenced-by-count":12,"title":["Cost\u2010Effectiveness Analysis of Long\u2010Term Intermittent Self\u2010Catheterization with Hydrophilic\u2010Coated and Uncoated Catheters in Patients with Spinal Cord Injury in Japan"],"prefix":"10.1111","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1138-5642","authenticated-orcid":false,"given":"Toyohiko","family":"WATANABE","sequence":"first","affiliation":[{"name":"Department of Urology Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences  Okayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shingo","family":"YAMAMOTO","sequence":"additional","affiliation":[{"name":"Department of Urology Hyogo College of Medicine  Nishinomiya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Momokazu","family":"GOTOH","sequence":"additional","affiliation":[{"name":"Department of Urology Nagoya University Graduate School of Medicine  Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tadanori","family":"SAITOH","sequence":"additional","affiliation":[{"name":"Nihon University School of Medicine  Itabashi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osamu","family":"YOKOYAMA","sequence":"additional","affiliation":[{"name":"Department of Urology University of Fukui Faculty of Medical Sciences  Fukui Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatsunori","family":"MURATA","sequence":"additional","affiliation":[{"name":"CRECON Medical Assessment Inc.  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