{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T00:05:48Z","timestamp":1769213148782,"version":"3.49.0"},"reference-count":23,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,6,28]],"date-time":"2017-06-28T00:00:00Z","timestamp":1498608000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["LUTS"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine outcomes after removal of two synthetic mid\u2010urethral slings (<jats:styled-content style=\"fixed-case\">MUS<\/jats:styled-content>) at a tertiary care center.<\/jats:p><\/jats:sec><jats:sec><jats:title><jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>ethods<\/jats:title><jats:p>Following <jats:styled-content style=\"fixed-case\">IRB<\/jats:styled-content> approval, a retrospective chart review of non\u2010neurogenic, symptomatic women requiring re\u2010operation after \u22652 <jats:styled-content style=\"fixed-case\">MUS<\/jats:styled-content> was performed. Data reviewed by a third party included: demographics, prior anti\u2010incontinence surgery, complications, pelvic\/urinary symptoms, subsequent investigations, surgical repair and outcomes (including <jats:styled-content style=\"fixed-case\">UDI<\/jats:styled-content>\u20106\/<jats:styled-content style=\"fixed-case\">IIQ<\/jats:styled-content>\u20107 questionnaires) at a minimum 6\u2009months follow\u2010up. Cure was defined as being continent, no dyspareunia, and no additional surgical therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Between 2007 and 2014, 21 women met the inclusion criteria. Mean age was 57\u2009years (range: 40\u201382) and mean follow\u2010up was 30.2\u2009months (range: 6\u201378). The majority of patients presented with one or more symptoms of voiding dysfunction (95%), urinary incontinence (86%), irritative voiding symptoms (62%), dyspareunia (57%), recurrent urinary tract infections (<jats:styled-content style=\"fixed-case\">UTIs)<\/jats:styled-content> (29%), vaginal extrusion (20%) and erosion involving the urinary tract (5%). Patients had a mean of 2 prior anti\u2010incontinence procedures (range 2\u20133). Over two\u2010thirds had a combination of retropubic and transobturator <jats:styled-content style=\"fixed-case\">MUS<\/jats:styled-content>. Mean number of pre\u2010operative investigations was 3.5 (1\u20136) including voiding cystourethrogram, cystoscopy and urodynamics. Two patients had complete remission, 14 partial remission, and five failed. Mean postoperative total <jats:styled-content style=\"fixed-case\">UDI<\/jats:styled-content>\u20106 and <jats:styled-content style=\"fixed-case\">IIQ<\/jats:styled-content>\u20107 scores at last clinic visit were 10 (range: 0\u201316\/<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content> 4.1) and 11 (range: 0\u201328\/<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content> 10.3), respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The management of women with suboptimal outcomes following two synthetic <jats:styled-content style=\"fixed-case\">MUS<\/jats:styled-content> from transvaginal excision results in modest symptomatic improvement but low permanent complete remission and frequent need for additional 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