{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:41:59Z","timestamp":1747186919753,"version":"3.40.5"},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,10,8]],"date-time":"2017-10-08T00:00:00Z","timestamp":1507420800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["LUTS"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>The aims of the present study were to evaluate the outcome of implantation of an <jats:styled-content style=\"fixed-case\">a<\/jats:styled-content>rtificial <jats:styled-content style=\"fixed-case\">u<\/jats:styled-content>rinary <jats:styled-content style=\"fixed-case\">s<\/jats:styled-content>phincter (<jats:styled-content style=\"fixed-case\">AUS<\/jats:styled-content>) in male patients with iatrogenic urinary incontinence and to analyse possible risk factors for resurgery, with particular focus on the effects of posterior urethral strictures (<jats:styled-content style=\"fixed-case\">US<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The outcomes of <jats:styled-content style=\"fixed-case\">AUS<\/jats:styled-content> implantation surgeries performed by 2 surgeons on consecutive patients between January 1999 and 2015 were evaluated retrospectively. Univariate analysis with <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ox proportional hazard regression was used to assess correlations between resurgery (explantation or substitution of the urethral cuff) and risk factors. Hazard ratios (HR) associated with <jats:styled-content style=\"fixed-case\">AUS<\/jats:styled-content> survival and 95% confidence intervals (CI) were calculated and <jats:styled-content style=\"fixed-case\">K<\/jats:styled-content>aplan\u2013<jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>eier were constructed. Patients who underwent resurgery for mechanical failure were excluded from the study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In all, 73 male patients were monitored for a maximum of 190\u2009months (median follow\u2010up duration 36\u2009months). The risk of resurgery was 3.75\u2010fold greater in patients with than without stenosis (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content> 3.75; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.47\u20109.59). In addition, <jats:styled-content style=\"fixed-case\">K<\/jats:styled-content>aplan\u2013<jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>eier survival curves showed a significantly shorter AUS survival time in patients with than without stenosis treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Prior treatment for <jats:styled-content style=\"fixed-case\">US<\/jats:styled-content> increases the relative risk of <jats:styled-content style=\"fixed-case\">AUS<\/jats:styled-content> failure. Despite not being an absolute contraindication for <jats:styled-content style=\"fixed-case\">AUS<\/jats:styled-content> implantation, we suggest that patients with previous treatment for <jats:styled-content style=\"fixed-case\">US<\/jats:styled-content> are informed of potential risks.<\/jats:p><\/jats:sec>","DOI":"10.1111\/luts.12205","type":"journal-article","created":{"date-parts":[[2017,10,9]],"date-time":"2017-10-09T00:52:38Z","timestamp":1507510358000},"source":"Crossref","is-referenced-by-count":1,"title":["Risk factors for resurgery in men with artificial urinary sphincter: <scp>R<\/scp>ole of urethral strictures"],"prefix":"10.1111","volume":"11","author":[{"given":"Paolo","family":"Traverso","sequence":"first","affiliation":[{"name":"Department of Urology, Ospedale Policlinico San Martino \u2013 Istituto di Ricerca e Cura a Carattere Scientifico per l'oncologia University of Genoa  Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4361-4523","authenticated-orcid":false,"given":"Guglielmo","family":"Mantica","sequence":"additional","affiliation":[{"name":"Department of Urology, Ospedale Policlinico San Martino \u2013 Istituto di Ricerca e Cura a Carattere Scientifico per l'oncologia University of Genoa  Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabio","family":"Gallo","sequence":"additional","affiliation":[{"name":"Section of Biostatistics, Department of Health Sciences University of Genova  Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Benelli","sequence":"additional","affiliation":[{"name":"Department of Urology G. Salvini Hospital  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Davide","family":"Becco","sequence":"additional","affiliation":[{"name":"Department of Urology, Ospedale Policlinico San Martino \u2013 Istituto di Ricerca e Cura a Carattere Scientifico per l'oncologia University of Genoa  Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aldo Franco","family":"De Rose","sequence":"additional","affiliation":[{"name":"Department of Urology, Ospedale Policlinico San Martino \u2013 Istituto di Ricerca e Cura a Carattere Scientifico per l'oncologia University of Genoa  Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alchiede","family":"Simonato","sequence":"additional","affiliation":[{"name":"Section of Urology, Department of Surgical, Oncological and Stomatological Sciences University of Palermo  Palermo Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,10,8]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)59647-0"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2012.11.034"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2011.11.051"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2006.10.062"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000152315.91444.d0"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-015-1662-9"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2014.05.043"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000133083.54934.ae"},{"key":"e_1_2_5_10_1","unstructured":"R Development Core Team(2016). 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