{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T04:45:19Z","timestamp":1754109919103,"version":"3.40.5"},"reference-count":17,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,1,11]],"date-time":"2018-01-11T00:00:00Z","timestamp":1515628800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["LUTS"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>The aim of the present study was to evaluate long\u2010term lower urinary tract dysfunction (LUTD) in pediatric patients who underwent ureteroneocystostomy due to vesicoureteral reflux.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The present retrospective study was performed on 61 patients. Patients were divided into 3 groups: Group 1 (n = 26), did not have LUTD; Group 2 (n = 23), had LUTD; and Group 3 (n = 12), was not toilet trained preoperatively. Patients were reassessed regarding de novo LUTD or the persistence of LUTD at least 7 years after the ureteroneocystostomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean patient age was 7 years (range 1\u201315) when ureteroneocystostomy was performed and the surgery was associated with a 92% success rate. The mean follow\u2010up period was 10 years (range 7\u201012\u2009years). Postoperative LUTD was present in 6 (23%), 12 (52%), and 1 (8.3%) patients in Groups 1, 2, and 3, respectively. The presence of LUTD before surgery and bilateral repair in the same setting were predictive risk factors for the presence of LUTD during the long\u2010term follow\u2010up. LUTD occurred at higher rate in Group 2 than in Groups 1 and 3 (52% vs. 23% and 8.3%, respectively; <jats:italic>P<\/jats:italic>\u2009=\u2009.015). The presence of de novo LUTD was significant in Group 1 compared with the presence of preoperative and postoperative LUTD (<jats:italic>P<\/jats:italic>\u2009=\u2009.031, Wilcoxon analysis).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>LUTD may not resolve after a ureteroneocystostomy, and additional therapy could be necessary. Due to the probability of damage to the ureterovesical nerve and\/or disturbed bladder dynamics, de novo LUTD may occur in patients with bilateral high\u2010grade reflux without LUTD before a ureteroneocystostomy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/luts.12213","type":"journal-article","created":{"date-parts":[[2018,1,11]],"date-time":"2018-01-11T06:34:30Z","timestamp":1515652470000},"source":"Crossref","is-referenced-by-count":2,"title":["Lower urinary tract dysfunction in pediatric patients after ureteroneocystostomy due to vesicoureteral reflux: Long\u2010term follow\u2010up"],"prefix":"10.1111","volume":"11","author":[{"given":"Kaya","family":"Horasanli","sequence":"first","affiliation":[{"name":"Urology Department Sisli Hamidiye Etfal Training and Research Hospital  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1506-9732","authenticated-orcid":false,"given":"G\u00f6ksel","family":"Bayar","sequence":"additional","affiliation":[{"name":"Urology Department Idil State Hospital  Sirnak Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huseyin","family":"Acinikli","sequence":"additional","affiliation":[{"name":"Urology Department Mersin City Hospital  Mersin Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cemil","family":"Kutsal","sequence":"additional","affiliation":[{"name":"Urology Department Sisli Hamidiye Etfal Training and Research Hospital  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sinan L.","family":"Kirecci","sequence":"additional","affiliation":[{"name":"Urology Department Sisli Hamidiye Etfal Training and Research Hospital  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayhan","family":"Dalkilic","sequence":"additional","affiliation":[{"name":"Urology Department Sisli Hamidiye Etfal Training and Research Hospital  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,1,11]]},"reference":[{"key":"e_1_2_5_2_1","unstructured":"Tekg\u00fclS DoganHS ErdemE et al. 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