{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T03:27:26Z","timestamp":1762918046768,"version":"3.40.5"},"reference-count":32,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["LUTS"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate perioperative parameters, early functional outcomes, and the safety profile in a matched\u2010pair analysis of lower urinary tract symptom (LUTS) patients treated with holmium laser enucleation of the prostate (HoLEP) or transurethral resection of the prostate (TURP).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a retrospective, matched\u2010pair analysis of 2011 men treated for LUTS in our institution from 2013 to 2017. In the final analysis, 197 patients (HoLEP n = 97; TURP n = 98) were matched for prostate size (50\u2009cc), age, and body mass index, and both cohorts were compared for demographic parameters, clinical outcomes, and adverse events according to the Clavien\u2010Dindo classification.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The perioperative assessment revealed a significantly higher tissue retrieval percentage of 75.4% (interquartile range [IQR] 64\u201081.2) after HoLEP in comparison to 47.3% (IQR 40\u201054.7) after TURP (<jats:italic>P<\/jats:italic> &lt;.001). A shorter surgery time was reported for TURP with a median time of 55.5\u2009minutes (IQR 48\u201070.5), whereas the median time for HoLEP was 62\u2009minutes (IQR 51\u201085) (<jats:italic>P<\/jats:italic> =.006). The median improvements in International Prostate Symptom Score (IPSS) were 11 points (IQR 5.5\u201017) and 7 points (IQR 3\u201014) for HoLEP and TURP, respectively (<jats:italic>P<\/jats:italic> =.007). Peak urinary flow rate (Q<jats:sub>max<\/jats:sub>) increased more after HoLEP (12.0\u2009mL\/s; IQR 7\u201023) than after TURP (8.5\u2009mL\/s; IQR 5\u201018.25) (<jats:italic>P<\/jats:italic> =.028). With an overall incidence of adverse events of 6% (n = 6) compared to 16% (n = 16%), significantly fewer complications occurred after HoLEP than after treatment with TURP (<jats:italic>P<\/jats:italic> &lt;.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>HoLEP is not only an attractive alternative for the enucleation of larger prostates, but it must be considered a size\u2010independent technique with the potential to outdo the current reference method TURP.<\/jats:p><\/jats:sec>","DOI":"10.1111\/luts.12290","type":"journal-article","created":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T12:48:34Z","timestamp":1569934114000},"page":"117-122","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["A matched\u2010pair analysis of patients with medium\u2010sized prostates (50\u2009cc) treated for male LUTS with HoLEP or TURP"],"prefix":"10.1111","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9872-7766","authenticated-orcid":false,"given":"Giuseppe","family":"Magistro","sequence":"first","affiliation":[{"name":"Department of Urology Ludwig\u2010Maximilians\u2010University of Munich  Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thilo","family":"Westhofen","sequence":"additional","affiliation":[{"name":"Department of Urology Ludwig\u2010Maximilians\u2010University of Munich  Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian G.","family":"Stief","sequence":"additional","affiliation":[{"name":"Department of Urology Ludwig\u2010Maximilians\u2010University of Munich  Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philipp","family":"Weinhold","sequence":"additional","affiliation":[{"name":"Department of Urology Ludwig\u2010Maximilians\u2010University of Munich  Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,10]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2011.06.065"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2007.04.074"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2011.10359.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.5489\/cuaj.5616"},{"key":"e_1_2_6_6_1","unstructured":"GravasS CornuJN DrakeMJ et al. 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