{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T05:36:48Z","timestamp":1769578608152,"version":"3.49.0"},"reference-count":13,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,8,12]],"date-time":"2020-08-12T00:00:00Z","timestamp":1597190400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["LUTS"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>To evaluate the presentation, risk factors, diagnostic workup, management, and outcomes of Macroplastique (MPQ) erosions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a retrospective chart review of women experiencing MPQ erosion at two tertiary care centers (United States and United Kingdom). Data collected included age, presenting symptoms, parity, comorbidities, hormone replacement therapy, sexual activity, and smoking status. Previous surgical history, time from MPQ injection, urine culture results, and cystoscopic and imaging findings were also reviewed. Development of stress urinary incontinence (SUI) after MPQ removal and subsequent SUI treatments were recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>From 2012 to 2018, 18 patients were identified with a median follow\u2010up time of 24\u2009months (interquartile range [IQR] 8\u201033). All patients presented with recurrent urinary tract infections (rUTI) and had cystoscopic evidence of MPQ erosion. The most common location of erosion was the bladder neck area (72%). Median time to presentation since MPQ injection was 14\u2009months (IQR 11\u201035). The majority of patients (72%) had a previous history of anti\u2010incontinence surgery. The overall success rate of endoscopic management defined as resolution of presenting symptoms including rUTI was 80%. The majority of patients (80%) developed recurrent SUI following MPQ resection with 33% requiring a subsequent autologous fascial sling placement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>MPQ erosions present predominantly with UTI, sometimes years after the original injection, and may necessitate endoscopic management with satisfactory results in most patients. Following excision of MPQ, these patients are highly likely to experience SUI recurrence and need to be appropriately counseled. Some may require additional subsequent autologous fascial sling placement for treatment of their SUI symptoms.<\/jats:p><\/jats:sec>","DOI":"10.1111\/luts.12337","type":"journal-article","created":{"date-parts":[[2020,8,12]],"date-time":"2020-08-12T09:42:22Z","timestamp":1597225342000},"page":"93-97","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Bladder neck and urethral erosions after Macroplastique injections"],"prefix":"10.1111","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2081-6416","authenticated-orcid":false,"given":"Dayron","family":"Rodr\u00edguez","sequence":"first","affiliation":[{"name":"Department of Urology University of Texas Southwestern Medical Center  Dallas Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ata","family":"Jaffer","sequence":"additional","affiliation":[{"name":"Department of Urology York Teaching Hospital  York UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mustafa","family":"Hilmy","sequence":"additional","affiliation":[{"name":"Department of Urology York Teaching Hospital  York UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7612-2042","authenticated-orcid":false,"given":"Philippe","family":"Zimmern","sequence":"additional","affiliation":[{"name":"Department of Urology University of Texas Southwestern Medical Center  Dallas Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,8,12]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"NICE Clinical guideline [CG171]. United Kingdom National Institute for health and care excellence. Urinary Incontinence in Women: Management;2015.https:\/\/www.nice.org.uk\/guidance\/cg171."},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-018-3839-4"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urols.2015.02.001"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1590\/s1677-5538.ibju.2019.0070"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-012-1825-9"},{"key":"e_1_2_9_7_1","first-page":"994","article-title":"Outcomes of Macroplastique injections for stress urinary incontinence after suburethral sling removal","volume":"39","author":"Rodriguez D","year":"2020","journal-title":"NeurourolUrodyn"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-017-3278-7"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/SPV.0000000000000495"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/SPV.0000000000000440"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/luts.12226"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2008.09.032"},{"issue":"7","key":"e_1_2_9_13_1","first-page":"CD003881","article-title":"Urethral injection therapy for urinary incontinence in women","volume":"7","author":"Kirchin V","year":"2017","journal-title":"Cochrane Database Syst Rev"},{"issue":"4","key":"e_1_2_9_14_1","first-page":"S12","article-title":"Complications of urethral bulking therapy for female stress urinary incontinence","volume":"38","author":"Kocjancic E","year":"2019","journal-title":"NeurourolUrodyn"}],"container-title":["LUTS: Lower Urinary Tract Symptoms"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fluts.12337","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/luts.12337","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/luts.12337","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/luts.12337","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,3]],"date-time":"2023-09-03T06:37:14Z","timestamp":1693723034000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/luts.12337"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,12]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1111\/luts.12337"],"URL":"https:\/\/doi.org\/10.1111\/luts.12337","archive":["Portico"],"relation":{},"ISSN":["1757-5664","1757-5672"],"issn-type":[{"value":"1757-5664","type":"print"},{"value":"1757-5672","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,12]]},"assertion":[{"value":"2020-05-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-29","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-08-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}