{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T15:53:18Z","timestamp":1787500398656,"version":"build-2736575974"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,9,25]],"date-time":"2021-09-25T00:00:00Z","timestamp":1632528000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["LUTS"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The bladder urothelium is not always impermeable. During sleep, the bladder might absorb urine in healthy individuals who sleep through the night. This study aimed to determine whether the bladder absorbs urine by using a method other than ultrasonic scanning and to simultaneously evaluate sleeping conditions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Eleven participants (five males, six females) aged 20 to 49\u2009years without lower urinary tract symptoms or urination while sleeping were enrolled. Bladder volume was estimated by studying the relationship between dilution and absorbance of indigo carmine dissolved in urine. A 12F Foley catheter was inserted into the bladder before sleep. Urine samples (5\u2009mL) were extracted at 2, 3, 4, 5, and 6\u00a0\n                      <jats:sc>am<\/jats:sc>\n                      sleep stages were monitored with a single\u2010channel portable electroencephalograph device.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The estimated bladder volume at 6\u00a0\n                      <jats:sc>am<\/jats:sc>\n                      and voided volume immediately after rising were significantly correlated (Spearman's\n                      <jats:italic>\u03c1<\/jats:italic>\n                      \u00a0=\u00a00.62,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.046). Eight participants (three males, five females) showed an absorption pattern of the estimated bladder volume change. In a male participant, the blue dye's strength gradually decreased until 4\u00a0\n                      <jats:sc>am<\/jats:sc>\n                      (estimated 859\u2009mL) and increased from 5\u00a0\n                      <jats:sc>am<\/jats:sc>\n                      (estimated 455\u2009mL). In another, the blue dye's strength increased at 4\u00a0\n                      <jats:sc>am<\/jats:sc>\n                      (estimated 449\u2009mL) vs at 3\u00a0\n                      <jats:sc>am<\/jats:sc>\n                      (estimated 757\u2009mL). In all participants, electroencephalograph data demonstrated that sleep was maintained despite having a full bladder.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The bladder absorbs urine and maintains an approximate volume of functional bladder capacity during sleep to avoid incontinence and maintain sleep in adults due to an urge to void urine during the sleep cycle.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/luts.12412","type":"journal-article","created":{"date-parts":[[2021,9,25]],"date-time":"2021-09-25T07:50:46Z","timestamp":1632556246000},"page":"72-77","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Assessment of bladder function for stabilizing urinary volume overnight with recording of brain waves (\n                    <scp>ABSORB<\/scp>\n                    study)"],"prefix":"10.1111","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2870-0466","authenticated-orcid":false,"given":"Kazumasa","family":"Torimoto","sequence":"first","affiliation":[{"name":"Department of Urology Nara Medical University  Kashihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chie","family":"Matsushita","sequence":"additional","affiliation":[{"name":"Department of Urology Saiseikai Chuwa Hospital  Sakurai Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshitaka","family":"Itami","sequence":"additional","affiliation":[{"name":"Department of Urology Medical Corporation Katsurakai HIRAO Hospital  Kashihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5243-6311","authenticated-orcid":false,"given":"Takashi","family":"Iwamoto","sequence":"additional","affiliation":[{"name":"Department of Urology Yamato Takada Municipal Hospital  Yamatotakada Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuya","family":"Owari","sequence":"additional","affiliation":[{"name":"Department of Urology Medical Corporation Katsurakai HIRAO Hospital  Kashihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6056-3820","authenticated-orcid":false,"given":"Daisuke","family":"Gotoh","sequence":"additional","affiliation":[{"name":"Department of Urology Nara Medical University  Kashihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makito","family":"Miyake","sequence":"additional","affiliation":[{"name":"Department of Urology Nara Medical University  Kashihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shunta","family":"Hori","sequence":"additional","affiliation":[{"name":"Department of Urology Nara Medical University  Kashihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasushi","family":"Nakai","sequence":"additional","affiliation":[{"name":"Department of Urology Nara Medical University  Kashihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsuya","family":"Aoki","sequence":"additional","affiliation":[{"name":"Department of Urology Nara Medical University  Kashihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuya","family":"Hirao","sequence":"additional","affiliation":[{"name":"Department of Urology Medical Corporation Katsurakai HIRAO Hospital  Kashihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hitoshi","family":"Momose","sequence":"additional","affiliation":[{"name":"Department of Urology Medical Corporation Katsurakai HIRAO Hospital  Kashihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobumichi","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Urology Nara Medical University  Kashihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyohide","family":"Fujimoto","sequence":"additional","affiliation":[{"name":"Department of Urology Nara Medical University  Kashihara 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epithelium","volume":"25","author":"Watanabe H","year":"2020","journal-title":"Nocturnal Enuresis Res"},{"key":"e_1_2_11_24_1","first-page":"2434","article-title":"Aquaporin\u20102 plays an important role in water transportation through the bladder wall in rats","volume":"37","author":"Morizawa Y","year":"2018","journal-title":"NeurourolUrodyn"}],"container-title":["LUTS: Lower Urinary Tract 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