{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:52:39Z","timestamp":1772160759734,"version":"3.50.1"},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,10,26]],"date-time":"2021-10-26T00:00:00Z","timestamp":1635206400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["LUTS"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate the outcomes of partial and total cystectomy in patients with refractory Hunner\u2010type interstitial cystitis (HIC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients with end\u2010stage HIC who underwent supratrigonal partial cystectomy with augmentation ileocystoplasty (PC\u2010CP) or total cystectomy with ileal conduit (TC\u2010IC) were identified retrospectively. Changes in the 11\u2010point numerical rating scale of bladder pain and in 7\u2010grade quality of life (QOL) scores were evaluated. Changes in the O'Leary and Sant's Symptom Index (OSSI) and O'Leary and Sant's Problem Index (OSPI) were analyzed in patients with PC\u2010CP. Peri\u2010 and postoperative complications and patient satisfaction with overall outcomes were examined.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Four patients (one female) underwent PC\u2010CP and 13 (nine females) underwent TC\u2010IC. Bladder pain persisted in three PC\u2010CP patients, but resolved completely in all TC\u2010IC patients. Pain scale and QOL scores improved significantly in patients with TC\u2010IC (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u2009.01), but not in those with PC\u2010CP. OSSI\/OSPI scores did not improve significantly in patients with PC\u2010CP. Three PC\u2010CP patients required clean intermittent catheterization due to voiding dysfunction or persistent pain. Two TC\u2010IC patients developed stricture of the ureteroileal anastomosis, resulting in permanent placement of a ureteral stent in one case and nephrostomy in the other. Satisfaction rate was higher in the TC\u2010IC than in the PC\u2010CP group (76.9% vs 25.0%,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u2009.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>TC\u2010IC provided reliable pain relief and improved QOL in patients with end\u2010stage HIC, but the small case number and limited methodology restrict interpretation of the results. Further studies are needed to identify appropriate candidates and optimal surgical procedures.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/luts.12416","type":"journal-article","created":{"date-parts":[[2021,10,27]],"date-time":"2021-10-27T02:05:11Z","timestamp":1635300311000},"page":"102-108","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Cystectomy for patients with\n                    <scp>Hunner\u2010<\/scp>\n                    type interstitial cystitis at a tertiary referral center in\n                    <scp>Japan<\/scp>"],"prefix":"10.1111","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1439-5640","authenticated-orcid":false,"given":"Yoshiyuki","family":"Akiyama","sequence":"first","affiliation":[{"name":"Department of Urology, Graduate School of Medicine The University of Tokyo  Tokyo 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