{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:42:29Z","timestamp":1747186949029,"version":"3.40.5"},"reference-count":31,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,11,18]],"date-time":"2021-11-18T00:00:00Z","timestamp":1637193600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["LUTS"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>This study aimed to determine whether Dahl salt\u2010sensitive rats fed a high\u2010salt diet would show features of nocturia due to nocturnal polyuria and to examine the efficacy of choreito (CRT) on nocturnal polyuria.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Dahl salt\u2010sensitive rats were divided into three groups. Group A was fed a 4% salt diet, group B a 2% salt diet, and group C a normal 0.3% salt diet. In groups \u03b1 and \u03b2, other rats were further divided into two groups: The rats in group \u03b1 were fed a 2% salt plus 3% CRT diet, and those in group \u03b2, were fed a 2% salt diet. Each rat was placed in an individual metabolic cage for 24\u2009hours every week for 6\u2009weeks. Water intake, urine production, voiding frequency, and voided volume per micturition were recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The systolic blood pressure increased in the group fed a 4% salt diet compared to groups fed with a 2% and 0.3% salt diet. The urinary volume was higher in the groups fed with 4% and 2% salt than in the group fed with 0.3% salt. Further, water intake in the group fed a 2% salt plus 3% CRT diet was significantly lower than that in the group fed with a 2% salt diet.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Dahl salt\u2010sensitive rats fed a 2% salt diet were candidates for a model of nocturnal polyuria. Using this model, we suggest that CRT reduces water intake in the active phase and contributes to water restriction in the treatment of nocturnal polyuria.<\/jats:p><\/jats:sec>","DOI":"10.1111\/luts.12418","type":"journal-article","created":{"date-parts":[[2021,11,19]],"date-time":"2021-11-19T01:01:02Z","timestamp":1637283662000},"page":"122-128","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The effects of choreito on a model of nocturnal polyuria using Dahl salt\u2010sensitive rats"],"prefix":"10.1111","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5243-6311","authenticated-orcid":false,"given":"Takashi","family":"Iwamoto","sequence":"first","affiliation":[{"name":"Department of Urology Nara Medical University Nara Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2870-0466","authenticated-orcid":false,"given":"Kazumasa","family":"Torimoto","sequence":"additional","affiliation":[{"name":"Department of Urology Nara Medical University Nara Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6056-3820","authenticated-orcid":false,"given":"Daisuke","family":"Gotoh","sequence":"additional","affiliation":[{"name":"Department of Urology Nara Medical University Nara Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shunta","family":"Hori","sequence":"additional","affiliation":[{"name":"Department of Urology Nara Medical University Nara Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasushi","family":"Nakai","sequence":"additional","affiliation":[{"name":"Department of Urology Nara Medical University Nara Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makito","family":"Miyake","sequence":"additional","affiliation":[{"name":"Department of Urology Nara Medical University Nara Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yohei","family":"Tokita","sequence":"additional","affiliation":[{"name":"Tsumura Kampo Research Laboratories, Kampo Research and Development Division Tsumura &amp; Co Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryohei","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Tsumura Kampo Research Laboratories, Kampo Research and Development Division Tsumura &amp; Co Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsuya","family":"Aoki","sequence":"additional","affiliation":[{"name":"Department of Urology Nara Medical University Nara Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiyohide","family":"Fujimoto","sequence":"additional","affiliation":[{"name":"Department of Urology Nara Medical University Nara Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,11,18]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2012.11.033"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2011.05.083"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/iju.13321"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.23929"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/535146"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.4.6.753"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/luts.12302"},{"key":"e_1_2_9_9_1","first-page":"1127","article-title":"A comparison between effects of pyruvate and herb medicines in preventing experimental oxalate urolithiasis in rats","volume":"32","author":"Ogawa Y","year":"1986","journal-title":"Hinyokika Kiyo"},{"key":"e_1_2_9_10_1","unstructured":"Japan Kampo Medicines Manufacturers Association.Table of the links of Kampo product informations in Japanese pharmacopoeia (JP) and\/or package insert (ver. 4.3).http:\/\/mpdb.nibiohn.go.jp\/kconsort\/kconsort.html. 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