{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T16:43:33Z","timestamp":1780418613424,"version":"3.54.1"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T00:00:00Z","timestamp":1700438400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["LUTS"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate longitudinal changes in lower urinary tract symptoms (LUTS) after artificial urinary sphincter (AUS) implantation in patients undergoing radiation therapy (RT) in comparison to those in non\u2010irradiated patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective study included 20 and 51 patients with and without a history of pelvic RT (RT and non\u2010RT group, respectively) who were treated with primary AUS implantation for post\u2010radical prostatectomy incontinence between 2010 and 2020. Longitudinal changes in the International Consultation on Incontinence Questionnaire\u2010Short Form (ICIQ\u2010SF), the International Prostate Symptom Score (IPSS), and the Overactive Bladder Symptom Score (OABSS) were calculated with a linear mixed model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the RT and non\u2010RT group, 18 (90%) and 48 (94%) patients achieved social continence, defined as daily pad use \u22641 at 1\u2009month after activation of AUS, respectively (<jats:italic>p<\/jats:italic>\u2009=\u2009.555). During the mean follow\u2010up of 38\u2009months, ICIQ\u2010SF, IPSS, and OABSS significantly improved after AUS implantation in both the RT and non\u2010RT groups. In the RT group, ICIQ\u2010SF, IPSS, and OABSS subsequently deteriorated with a slope of 0.62\/year (<jats:italic>p<\/jats:italic>\u2009=\u2009.010), 0.55\/year (<jats:italic>p<\/jats:italic>\u2009=\u2009.025), and 0.30\/year (<jats:italic>p<\/jats:italic>\u2009=\u2009.007), respectively. In the non\u2010RT group, no significant longitudinal changes in subsequent IPSS and OABSS were observed, although ICIQ\u2010SF significantly deteriorated (0.43\/year, <jats:italic>p<\/jats:italic>\u2009=\u2009.006). Comparing between the groups, the slopes of IPSS and OABSS were significantly greater in the RT group than in the non\u2010RT group (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001, and .015, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Longitudinal deterioration in LUTS that improved immediately after AUS implantation was observed in patients with a history of pelvic RT, but not in patients without a history of pelvic RT.<\/jats:p><\/jats:sec>","DOI":"10.1111\/luts.12507","type":"journal-article","created":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T21:53:53Z","timestamp":1700603633000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Longitudinal deterioration in lower urinary tract symptoms after artificial urinary sphincter implantation in patients with a history of pelvic radiation therapy"],"prefix":"10.1111","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9084-7798","authenticated-orcid":false,"given":"Madoka","family":"Kataoka","sequence":"first","affiliation":[{"name":"Department of Urology Tokyo Medical and Dental University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0245-8934","authenticated-orcid":false,"given":"Minato","family":"Yokoyama","sequence":"additional","affiliation":[{"name":"Department of Urology Tokyo Medical and Dental University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9319-1373","authenticated-orcid":false,"given":"Yuma","family":"Waseda","sequence":"additional","affiliation":[{"name":"Department of Urology Tokyo Medical and Dental University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0230-6367","authenticated-orcid":false,"given":"Masaya","family":"Ito","sequence":"additional","affiliation":[{"name":"Department of Urology Tokyo Medical and Dental University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2738-9792","authenticated-orcid":false,"given":"Masaki","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Department of Urology Tokyo Medical and Dental University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9454-3345","authenticated-orcid":false,"given":"Motohiro","family":"Fujiwara","sequence":"additional","affiliation":[{"name":"Department of Urology Tokyo Medical and Dental University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4931-2489","authenticated-orcid":false,"given":"Yuki","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Department of Urology Tokyo Medical and Dental University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7118-5522","authenticated-orcid":false,"given":"Yudai","family":"Ishikawa","sequence":"additional","affiliation":[{"name":"Department of Urology Tokyo Medical and Dental University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2741-8338","authenticated-orcid":false,"given":"Shohei","family":"Fukuda","sequence":"additional","affiliation":[{"name":"Department of Urology Tokyo Medical and Dental University  Tokyo 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