{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T06:00:36Z","timestamp":1774591236392,"version":"3.50.1"},"reference-count":17,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T00:00:00Z","timestamp":1772755200000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100008497","name":"Boston Scientific Corporation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008497","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["LUTS"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Rez\u016bm has become an increasingly popular surgical approach for treating bladder outlet obstruction. Despite the practice of routinely placing a Foley catheter, successful TWOC (Trial Without Catheter) remains variable. This study seeks to identify the TWOC failure incidence and risk factors to inform clinical decisions and enhance patient counseling.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective review of non\u2010catheter dependent patients who underwent Rez\u016bm therapy between April 2019 and June 2023 in two high\u2010volume Canadian centers. All patients received a urinary catheter post\u2010treatment. International Prostate Symptom Score (IPSS), QoL, Qmax, and PVR were evaluated. Risk factors for TWOC failure were determined through logistic regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Out of 406 patients, 99 patients (24.4%) failed TWOC on the first attempt. Median time to TWOC was 7\u2009days (range 3\u201330\u2009days). Successful and failure groups had no significant difference in terms of average catheterization time, baseline prostate volume, PVR, or total number of injections per prostate volume ratio. A higher rate of UTIs was observed in the TWOC failure group (10.6% vs. 2.6%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003). During the 12\u2010month follow\u2010up period, 12 patients developed episodes of urinary retention following Rez\u016bm therapy. Baseline PVR was not a risk factor for failed TWOC in our cohort (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.95). Higher IPSS was a predictor for TWOC failure (OR 1.04 95% CI: 1.01\u20131.08).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>About one in four patients failed the first TWOC after Rez\u016bm therapy. High baseline IPSS was identified as the only risk factor for TWOC failure in our cohort. Despite this, overall urinary symptoms improved in all patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/luts.70054","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T18:42:48Z","timestamp":1772995368000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Failed Trial Without Catheter Post Rez\u016bm in Non\u2010Catheter Dependent Patients: Risk Factors From the Canadian Rez\u016bm Registry"],"prefix":"10.1111","volume":"18","author":[{"given":"Omar","family":"Buksh","sequence":"first","affiliation":[{"name":"Division of Urology, Department of Surgery University of Toronto  Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8075-8433","authenticated-orcid":false,"given":"Roseanne","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Division of Urology, Department of Surgery University of Toronto  Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-2867-9723","authenticated-orcid":false,"given":"Mario Henrique Bitar","family":"Siqueira","sequence":"additional","affiliation":[{"name":"Division of Urology, Department of Surgery University of Toronto  Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naeem","family":"Bhojani","sequence":"additional","affiliation":[{"name":"Division of Urology Centre Hospitalier de l\u2019Universit\u00e9 de Montr\u00e9al (CHUM)  Montr\u00e9al Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bilal","family":"Chughtai","sequence":"additional","affiliation":[{"name":"Plainview Hospital, Smith Institute of Urology, Northwell Health  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin C.","family":"Zorn","sequence":"additional","affiliation":[{"name":"BPH Canada, Prostate Surgical Institute  Montreal Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1507-7783","authenticated-orcid":false,"given":"Dean S.","family":"Elterman","sequence":"additional","affiliation":[{"name":"Division of Urology, Department of Surgery University of Toronto  Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,3,6]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ucl.2016.04.001"},{"key":"e_1_2_9_3_1","first-page":"9787","article-title":"The Rez\u016bm System: A Minimally Invasive Water Vapor Thermal Therapy for Obstructive Benign Prostatic Hyperplasia","volume":"26","author":"Cantrill C. H.","year":"2019","journal-title":"Canadian Journal of Urology"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11884-010-0067-2"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.21037\/tau.2019.10.01"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/1756287211426301"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euf.2018.02.011"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/luts.12435"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.5152\/tud.2021.21128"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2015.10.181"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2015.05.046"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/luts.12483"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1089\/end.2022.0490"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(00)01021-9"},{"key":"e_1_2_9_15_1","first-page":"11668","article-title":"Comparison of IPSS Score and Voiding Parameters in Men Presenting With LUTS","volume":"30","author":"Kohler T. S.","year":"2023","journal-title":"Canadian Journal of Urology"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.143.6.551"},{"key":"e_1_2_9_17_1","volume-title":"Male Urinary Retention","author":"Dougherty J. 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