{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T12:59:53Z","timestamp":1785416393503,"version":"3.56.0"},"reference-count":34,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T00:00:00Z","timestamp":1781049600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T00:00:00Z","timestamp":1781049600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["LUTS"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Aquablation therapy is an effective treatment for benign prostatic obstruction. However, its functional outcomes in older patients remain underexplored. In this study, we aimed to compare improvements in lower urinary tract symptoms (LUTS) after Aquablation therapy in patients aged \u2265\u200975 and \u2264\u200974\u2009years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We retrospectively analyzed data from 103 men with moderate\u2010to\u2010severe LUTS who underwent Aquablation between 2023 and 2025. Patients were stratified into two age groups (years): \u2264\u200974 (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200972) and \u2265\u200975 (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200931). Primary outcomes included changes in the International Prostate Symptom Score (IPSS), IPSS\u2010Quality of Life (IPSS\u2010QoL), maximum urinary flow rate (Qmax), and post\u2010void residual (PVR) from baseline to 3\u2009months postoperatively. Secondary outcomes included transfusion and complication rates.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      After 3\u2009months, both groups showed significant improvements in total IPSS (\u221210.46 and \u22127.38 in those aged \u2264\u200974 and \u2265\u200975\u2009years, respectively), QoL (\u22122.32 vs. \u22122.33), Qmax (+8.67 vs. +6.03\u2009mL\/s), and PVR (\u221289.1 vs. \u221275.3\u2009mL; all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). In the \u2265\u200975 group, voiding subscores, including incomplete emptying, intermittency, weak stream, and straining, improved significantly (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05), whereas storage symptoms, including frequency, urgency, and nocturia, did not (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.07, 0.6, and 0.7, respectively). In patients aged \u2264\u200974\u2009years, both voiding and storage symptom subscores improved significantly. No significant differences in operative time, transfusion rate, or complication rate were observed between groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Aquablation therapy is a safe and effective surgical option for patients aged \u2265\u200975\u2009years. In this older population, although storage symptoms were less treatment\u2010responsive, substantial improvements in voiding symptoms and overall QoL were achieved.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/luts.70072","type":"journal-article","created":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T04:56:44Z","timestamp":1781153804000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Does Aquablation Therapy Improve Lower Urinary Tract Symptoms in Patients Aged \u2265\u200975\u2009Years With Benign Prostatic Obstruction?"],"prefix":"10.1111","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1428-9736","authenticated-orcid":false,"given":"Shin","family":"Koike","sequence":"first","affiliation":[{"name":"Department of Urology Itabashi Chuo Medical Center  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1633-784X","authenticated-orcid":false,"given":"Yu","family":"Ozawa","sequence":"additional","affiliation":[{"name":"Department of Urology Itabashi Chuo Medical Center  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunao","family":"Nohara","sequence":"additional","affiliation":[{"name":"Department of Urology Itabashi Chuo Medical Center  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kei","family":"Ushijima","sequence":"additional","affiliation":[{"name":"Department of Urology Itabashi Chuo Medical Center  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keita","family":"Okamoto","sequence":"additional","affiliation":[{"name":"Department of Urology Itabashi Chuo Medical Center  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiaki","family":"Kayaba","sequence":"additional","affiliation":[{"name":"Department of Urology Itabashi Chuo Medical Center  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masumi","family":"Yamada","sequence":"additional","affiliation":[{"name":"Department of Urology Itabashi Chuo Medical Center  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keisuke","family":"Aoki","sequence":"additional","affiliation":[{"name":"Department of Urology Itabashi Chuo Medical Center  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Odagaki","sequence":"additional","affiliation":[{"name":"Department of Urology Itabashi Chuo Medical Center  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideo","family":"Sakamoto","sequence":"additional","affiliation":[{"name":"Department of Urology Itabashi Chuo Medical Center  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1507-7783","authenticated-orcid":false,"given":"Dean","family":"Elterman","sequence":"additional","affiliation":[{"name":"Division of Urology University Health Network, University of Toronto  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kunihiko","family":"Yoshioka","sequence":"additional","affiliation":[{"name":"Department of Urology Itabashi Chuo Medical Center  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,10]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464\u2010410x.1999.00966.x"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajur.2017.06.004"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/iju.15551"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ucl.2021.07.007"},{"issue":"6","key":"e_1_2_11_6_1","first-page":"8590","article-title":"How I Do It: Aquablation of the Prostate Using the AQUABEAM System","volume":"23","author":"MacRae C.","year":"2016","journal-title":"Canadian Journal of Urology"},{"issue":"5","key":"e_1_2_11_7_1","first-page":"11650","article-title":"Aquablation Versus TURP: 5\u2010Year Outcomes of the WATER Randomized Clinical Trial for Prostate Volumes 50\u201380 mL","volume":"30","author":"Oumedjbeur K.","year":"2023","journal-title":"Canadian Journal of Urology"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/0974\u20107796.148595"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2019.06.025"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/iju.15651"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/iju.70373"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2022.07.007"},{"issue":"2","key":"e_1_2_11_13_1","first-page":"10610","article-title":"Focal Bladder Neck Cautery Associated With Low Rate of Post\u2010Aquablation Bleeding","volume":"28","author":"Elterman D. 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