{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T12:59:51Z","timestamp":1785416391091,"version":"3.56.0"},"reference-count":10,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T00:00:00Z","timestamp":1784678400000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["LUTS"],"published-print":{"date-parts":[[2026,7]]},"abstract":"ABSTRACT<\/jats:title>\n \n Objectives<\/jats:title>\n To compare minimally invasive surgical therapies (MISTs) for benign prostatic obstruction (BPO) using probabilistic multicriteria decision analysis that integrates heterogeneous clinical outcomes under varying stakeholder priorities.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n This secondary analysis was derived from a published network meta\u2010analysis. Three treatments\u2014monopolar transurethral resection of the prostate (mTURP), prostatic urethral lift (PUL), and water vapor thermal therapy (WVTT)\u2014were compared across six criteria: International Prostate Symptom Score (IPSS), IPSS Quality of Life, maximum urinary flow rate (\n Q<\/jats:italic>\n max<\/jats:sub>\n ), postvoid residual urine volume (PVR), and two domains of the Male Sexual Health Questionnaire Short Form. Treatment effects were sampled using a Monte Carlo simulation (50\u2009000 iterations) and mapped to a 0\u20131 scale using clinically interpretable anchors. Five weighting scenarios produced preference probabilities and net advantages with 95% uncertainty intervals (UI). Anchor perturbation and correlation sensitivity analyses assessed robustness.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Under equal weights, WVTT had the highest\n P<\/jats:italic>\n (best) (54.1%), followed by mTURP (25.8%) and PUL (20.1%); all pairwise UIs crossed zero. Under efficacy weights, mTURP had the highest\n P<\/jats:italic>\n (best) (88.0%; net advantage vs. PUL: 0.124, 95% UI: 0.034\u20130.214), driven by superiority in\n Q<\/jats:italic>\n \n max<\/jats:italic>\n <\/jats:sub>\n and PVR. Under sexual function weights, mTURP was rarely preferred (\n P<\/jats:italic>\n [best]\u2009<\u20090.1%), whereas PUL and WVTT achieved\n P<\/jats:italic>\n (best) of 45.3% and 54.7%, respectively. Rankings were robust in both anchor perturbation and correlation sensitivity analyses.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Within short\u2010term (3\u20136\u2009month) data, MIST preference for BPO depends on clinical priorities. mTURP is favored when urodynamic outcomes are emphasized; PUL and WVTT are preferred when preservation of sexual function is prioritized. This framework supports preference\u2010sensitive shared decision\u2010making, although the findings are provisional pending long\u2010term data.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/luts.70083","type":"journal-article","created":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T13:54:04Z","timestamp":1784728444000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Probabilistic Multicriteria Decision Analysis of Minimally Invasive Treatments for Benign Prostatic Obstruction: A Secondary Analysis of Network Meta\u2010Analysis Data"],"prefix":"10.1111","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2300-8446","authenticated-orcid":false,"given":"Shugo","family":"Yajima","sequence":"first","affiliation":[{"name":"Department of Urology National Cancer Center Hospital East Chiba Japan"},{"name":"Department of Urology Institute of Science Tokyo Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2757-8083","authenticated-orcid":false,"given":"Soichiro","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Department of Urology Institute of Science Tokyo Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2275-4527","authenticated-orcid":false,"given":"Wei","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Urology Institute of Science Tokyo Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7548-1580","authenticated-orcid":false,"given":"Hiroshi","family":"Fukushima","sequence":"additional","affiliation":[{"name":"Department of Urology Institute of Science Tokyo Tokyo 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