{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T05:59:40Z","timestamp":1790315980117,"version":"4.1.0"},"reference-count":19,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T00:00:00Z","timestamp":1787529600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T00:00:00Z","timestamp":1787529600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["LUTS"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Evidence regarding the safety of water vapor energy (WAVE) therapy in patients continuing antithrombotic (AT) agents remains limited. This study compared the safety and efficacy of WAVE therapy between patients receiving AT therapy and those not receiving such therapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This retrospective comparative study included 103 consecutive patients who underwent WAVE therapy at a single institution between February 2023 and October 2024. Patients were divided into an AT group (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200936) and a non\u2010AT group (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200967). All AT agents continued throughout the perioperative period. Postoperative complications were graded according to the Clavien\u2013Dindo classification. Changes in symptom scores and uroflowmetry parameters were evaluated at baseline and at 3 and 6\u2009months after treatment in patients without a preoperative indwelling catheter.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Baseline characteristics were generally similar between the two groups, although patients in the AT group were significantly older than those in the non\u2010AT group. Early postoperative bleeding events were comparable (11.1% in the AT group vs. 4.5% in the non\u2010AT group,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.24), and no grade \u2265\u20093 complications occurred in either group. Late complications occurred only in the non\u2010AT group (6.0%). In the overall cohort, the median IPSS total score decreased from 18.5 (interquartile range: 12.0\u201325.0) at baseline to 9.0 (3.0\u201312.8) and 6.0 (3.0\u201310.8) at 3 and 6\u2009months, respectively. Post\u2010void residual volume decreased from 111 (interquartile range: 52.8\u2013180) mL at baseline to 55.5 (27.3\u2013102) and 50.5 (24.5\u201392.3) mL. These improvements were comparable between groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>WAVE therapy appeared feasible in patients who continued AT therapy, with acceptable short\u2010term safety and symptomatic improvement.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/luts.70094","type":"journal-article","created":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T04:12:48Z","timestamp":1787631168000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Safety and Efficacy of Rez\u016bm Water Vapor Energy Therapy for Benign Prostatic Hyperplasia With Continued Antithrombotic Therapy: A Comparative Study"],"prefix":"10.1111","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-3928-0486","authenticated-orcid":false,"given":"Naoki","family":"Fujisawa","sequence":"first","affiliation":[{"name":"Department of Urology IMS Fujimi General Hospital  Fujimi Japan"},{"name":"Department of Urology Jichi Medical University Saitama Medical Center  Saitama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9464-6424","authenticated-orcid":false,"given":"Satoshi","family":"Washino","sequence":"additional","affiliation":[{"name":"Department of Urology Jichi Medical University Saitama Medical Center  Saitama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuka","family":"Yasuda","sequence":"additional","affiliation":[{"name":"Department of Urology IMS Fujimi General Hospital  Fujimi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigetoshi","family":"Maiya","sequence":"additional","affiliation":[{"name":"Department of Urology IMS Fujimi General Hospital  Fujimi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuo","family":"Shinozaki","sequence":"additional","affiliation":[{"name":"Department of Urology IMS Fujimi General Hospital  Fujimi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,24]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)13073-5"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.g4474"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1185\/030079906X167345"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/1756287211426301"},{"issue":"4","key":"e_1_2_10_6_1","first-page":"3807","article-title":"Meta\u2010Analysis of the Effect of Antithrombotic Drugs on Perioperative Bleeding in BPH Surgery","volume":"20","author":"He Q.","year":"2020","journal-title":"Experimental and Therapeutic Medicine"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-2298"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2015.03.021"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/iju.70052"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2018.12.041"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000133083.54934.ae"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-024-05439-7"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.21037\/tau-21-1005"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1089\/end.2017.0092"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2014.04.103"},{"issue":"3","key":"e_1_2_10_16_1","first-page":"8802","article-title":"Five Year Results of the Prospective Randomized Controlled Prostatic Urethral L.I.F.T. Study","volume":"24","author":"Roehrborn C. G.","year":"2017","journal-title":"Canadian Journal of Urology"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41391-018-0118-x"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-023-04395-y"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/bco2.70170"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/iju.15558"}],"container-title":["LUTS: Lower Urinary Tract Symptoms"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/luts.70094","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/luts.70094","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/luts.70094","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T05:27:32Z","timestamp":1790314052000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/luts.70094"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,24]]},"references-count":19,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1111\/luts.70094"],"URL":"https:\/\/doi.org\/10.1111\/luts.70094","archive":["Portico"],"relation":{},"ISSN":["1757-5664","1757-5672"],"issn-type":[{"value":"1757-5664","type":"print"},{"value":"1757-5672","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,24]]},"assertion":[{"value":"2026-03-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-14","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70094"}}