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Newborn excess weight loss (<jats:styled-content style=\"fixed-case\">EWL<\/jats:styled-content>) could trigger milk supply concern and anxiety and might be amenable to modification. Our objective was to determine the relationship between <jats:styled-content style=\"fixed-case\">EWL<\/jats:styled-content> and the development of milk supply concern and anxiety and the effect of such development on breastfeeding duration. We conducted a cohort analysis using data previously obtained from a randomised controlled trial comparing two post\u2010hospital discharge follow\u2010up strategies. For 1107 well, singleton infants born at \u226534 weeks, we extracted data on all inpatient infant weights. <jats:styled-content style=\"fixed-case\">EWL<\/jats:styled-content> was defined as the loss of \u226510% of birthweight. We surveyed mothers to obtain data on state anxiety and milk supply concern at birth and at 2 weeks. Our final outcome was breastfeeding at 6 months. Seventy (6.3%) infants developed <jats:styled-content style=\"fixed-case\">EWL<\/jats:styled-content> during the birth hospitalisation. At 2 weeks, milk supply concern and positive anxiety screen were more common (42% and 18%, respectively) among mothers whose infants had had <jats:styled-content style=\"fixed-case\">EWL<\/jats:styled-content> than among mothers whose infants had not had <jats:styled-content style=\"fixed-case\">EWL<\/jats:styled-content> (20% and 6%, respectively) (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001 for each comparison). Mothers with milk supply concern at 2 weeks were much less likely to be breastfeeding at 6 months, with odds ratio of 0.47 (0.30, 0.74) in multivariate analysis. <jats:styled-content style=\"fixed-case\">EWL<\/jats:styled-content> may increase milk supply concern and anxiety and these may reduce breastfeeding duration. Ameliorating <jats:styled-content style=\"fixed-case\">EWL<\/jats:styled-content> might alleviate milk supply concern and anxiety and improve breastfeeding duration.<\/jats:p>","DOI":"10.1111\/mcn.12171","type":"journal-article","created":{"date-parts":[[2015,3,18]],"date-time":"2015-03-18T16:17:41Z","timestamp":1426695461000},"page":"463-472","source":"Crossref","is-referenced-by-count":36,"title":["Relationship of newborn weight loss to milk supply concern and anxiety: the impact on breastfeeding duration"],"prefix":"10.1111","volume":"12","author":[{"given":"Valerie J.","family":"Flaherman","sequence":"first","affiliation":[{"name":"Department of Pediatrics School of Medicine University of California  San Francisco California USA"},{"name":"Department of Epidemiology and Biostatistics School of Medicine University of California  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica S.","family":"Beiler","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Penn State College of Medicine  Hershey Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael D.","family":"Cabana","sequence":"additional","affiliation":[{"name":"Department of Pediatrics School of Medicine University of California  San Francisco California USA"},{"name":"Department of Epidemiology and Biostatistics School of Medicine University of California  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian M.","family":"Paul","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Penn State College of Medicine  Hershey Pennsylvania USA"},{"name":"Department of Public Health Sciences Penn State College of Medicine  Hershey Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,3,18]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1089\/bfm.2009.9991"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/0890334413504244"},{"key":"e_1_2_10_4_1","first-page":"7","article-title":"Why do women stop breastfeeding? 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