{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T19:17:10Z","timestamp":1777490230589,"version":"3.51.4"},"reference-count":32,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,3,18]],"date-time":"2015-03-18T00:00:00Z","timestamp":1426636800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"UAB Diabetes Research Center","award":["P30DK079626"],"award-info":[{"award-number":["P30DK079626"]}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["K01DK090126"],"award-info":[{"award-number":["K01DK090126"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"name":"UAB Nutrition Obesity Research Center","award":["P30DK056336"],"award-info":[{"award-number":["P30DK056336"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Maternal &amp; Child Nutrition"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Obesity and late\u2010night food consumption are associated with impaired glucose tolerance. Late\u2010night carbohydrate consumption may be particularly detrimental during late pregnancy because insulin sensitivity declines as pregnancy progresses. Further, women who were obese (<jats:styled-content style=\"fixed-case\">Ob<\/jats:styled-content>) prior to pregnancy have lower insulin sensitivity than do women of normal weight (<jats:styled-content style=\"fixed-case\">NW<\/jats:styled-content>). The aim of this study is to test the hypothesis that night\u2010time carbohydrate consumption is associated with poorer glucose tolerance in late pregnancy and that this association would be exacerbated among <jats:styled-content style=\"fixed-case\">Ob<\/jats:styled-content> women. Forty non\u2010diabetic <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>frican <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>merican women were recruited based upon early pregnancy body mass index (<jats:styled-content style=\"fixed-case\">NW<\/jats:styled-content>, &lt;25\u2009kg\u2009m<jats:sup>\u22122<\/jats:sup>; <jats:styled-content style=\"fixed-case\">Ob<\/jats:styled-content>,\u2009\u226530\u2009kg\u2009m<jats:sup>\u22122<\/jats:sup>). Third trimester free\u2010living dietary intake was assessed by food diary, and indices of glucose tolerance and insulin action were assessed during a 75\u2010g oral glucose tolerance test. Women in the <jats:styled-content style=\"fixed-case\">Ob<\/jats:styled-content> group reported greater average 24\u2010h energy intake (3055\u2009kcal vs. 2415\u2009kcal, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). Across the whole cohort, night\u2010time, but not day\u2010time, carbohydrate intake was positively associated with glucose concentrations after the glucose load and inversely associated with early phase insulin secretion (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). Multiple linear regression modelling within each weight group showed that the associations among late\u2010night carbohydrate intake, glucose concentrations and insulin secretion were present only in the <jats:styled-content style=\"fixed-case\">Ob<\/jats:styled-content> group. This is the first study to report an association of night\u2010time carbohydrate intake specifically on glucose tolerance and insulin action during pregnancy. If replicated, these results suggest that late\u2010night carbohydrate intake may be a potential target for intervention to improve metabolic health of <jats:styled-content style=\"fixed-case\">Ob<\/jats:styled-content> women in late pregnancy.<\/jats:p>","DOI":"10.1111\/mcn.12181","type":"journal-article","created":{"date-parts":[[2015,3,18]],"date-time":"2015-03-18T16:17:49Z","timestamp":1426695469000},"page":"688-698","source":"Crossref","is-referenced-by-count":20,"title":["Association of late\u2010night carbohydrate intake with glucose tolerance among pregnant <scp>A<\/scp>frican <scp>A<\/scp>merican women"],"prefix":"10.1111","volume":"12","author":[{"given":"Paula C.","family":"Chandler\u2010Laney","sequence":"first","affiliation":[{"name":"Department of Nutrition Sciences University of Alabama  Birmingham Alabama USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camille R.","family":"Schneider","sequence":"additional","affiliation":[{"name":"Department of Nutrition Sciences University of Alabama  Birmingham Alabama USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara A.","family":"Gower","sequence":"additional","affiliation":[{"name":"Department of Nutrition Sciences University of Alabama  Birmingham Alabama USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wesley M.","family":"Granger","sequence":"additional","affiliation":[{"name":"Department of Clinical and Diagnostic Sciences University of Alabama  Birmingham Alabama USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa S.","family":"Mancuso","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Center for Women's Reproductive Health University of Alabama  Birmingham Alabama USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph R.","family":"Biggio","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Center for Women's Reproductive Health University of Alabama  Birmingham Alabama 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