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Asymptomatic infections can restrict growth, but little is known about their role in global stunting prevalence. We investigated factors related to length\u2010for\u2010age <jats:italic>Z<\/jats:italic>\u2010score (LAZ) at 24 months by constructing an interconnected network of various infections, biomarkers of inflammation (as assessed by alpha\u20101\u2010acid glycoprotein [AGP]), and growth (insulin\u2010like growth factor 1\u00a0[IGF\u20101] and collagen X biomarker [CXM]) at 18 months, as well as other children, maternal, and household level factors. Among 604 children, there was a continuous decline in mean LAZ and increased mean length deficit from birth to 24 months. At 18 months\u00a0of age, the percentage of asymptomatic children who carried each pathogen was: 84.5% enterovirus, 15.5% parechovirus, 7.7% norovirus, 4.6% rhinovirus, 0.6% rotavirus, 69.6% <jats:italic>Campylobacter<\/jats:italic>, 53.8% <jats:italic>Giardia lamblia<\/jats:italic>, 11.9% malaria parasites, 10.2% <jats:italic>Shigella<\/jats:italic>, and 2.7% <jats:italic>Cryptosporidium<\/jats:italic>. The mean plasma IGF\u20101 concentration was 12.5\u2009ng\/ml and 68% of the children had systemic inflammation (plasma AGP concentration &gt;1\u2009g\/L). <jats:italic>Shigella<\/jats:italic> infection was associated with lower LAZ at 24 months through both direct and indirect pathways, whereas enterovirus, norovirus, <jats:italic>Campylobacter<\/jats:italic>, <jats:italic>Cryptosporidium<\/jats:italic>, and malaria infections were associated with lower LAZ at 24 months indirectly, predominantly through increased systemic inflammation and reduced plasma IGF\u20101 and CXM concentration at 18 months.<\/jats:p>","DOI":"10.1111\/mcn.13417","type":"journal-article","created":{"date-parts":[[2022,9,16]],"date-time":"2022-09-16T07:37:57Z","timestamp":1663313877000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Association between asymptomatic infections and linear growth in 18\u201324\u2010month\u2010old Malawian children"],"prefix":"10.1111","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0008-8295","authenticated-orcid":false,"given":"Juho","family":"Luoma","sequence":"first","affiliation":[{"name":"Center for Child, Adolescent and Maternal Health Research, Faculty of Medicine and Health Technology Tampere University  Tampere Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0973-9533","authenticated-orcid":false,"given":"Laura","family":"Adubra","sequence":"additional","affiliation":[{"name":"Center for Child, Adolescent and Maternal Health Research, Faculty of Medicine and Health Technology Tampere University  Tampere Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per","family":"Ashorn","sequence":"additional","affiliation":[{"name":"Center for Child, Adolescent and Maternal Health Research, Faculty of Medicine and Health Technology Tampere University  Tampere Finland"},{"name":"Department of Paediatrics Tampere University Hospital  Tampere Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1720-868X","authenticated-orcid":false,"given":"Ulla","family":"Ashorn","sequence":"additional","affiliation":[{"name":"Center for Child, Adolescent and Maternal Health Research, Faculty of Medicine and Health Technology Tampere University  Tampere Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaden","family":"Bendabenda","sequence":"additional","affiliation":[{"name":"School of Public Health and Family Medicine, College of Medicine University of Malawi  Blantyre Malawi"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn G.","family":"Dewey","sequence":"additional","affiliation":[{"name":"Department of Nutrition, Institute for Global Nutrition University of California  Davis California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lotta","family":"Hallamaa","sequence":"additional","affiliation":[{"name":"Center for Child, Adolescent and Maternal Health Research, Faculty of Medicine and Health Technology Tampere University  Tampere Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan","family":"Coghlan","sequence":"additional","affiliation":[{"name":"Research Center, Shriners Hospitals for Children  Portland Oregon USA"},{"name":"Department of Molecular and Medical Genetics Oregon Health and Science University  Portland Oregon USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William A.","family":"Horton","sequence":"additional","affiliation":[{"name":"Research Center, Shriners Hospitals for Children  Portland Oregon USA"},{"name":"Department of Molecular and Medical Genetics Oregon Health and Science University  Portland Oregon USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heikki","family":"Hy\u00f6ty","sequence":"additional","affiliation":[{"name":"Department of Virology, Faculty of Medicine and Health Technology Tampere University  Tampere Finland"},{"name":"Fimlab Ltd. 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