{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T00:45:09Z","timestamp":1785026709867,"version":"3.55.0"},"reference-count":39,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T00:00:00Z","timestamp":1696550400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000865","name":"Bill and Melinda Gates Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000200","name":"United States Agency for International Development","doi-asserted-by":"publisher","award":["7200AA18C00070"],"award-info":[{"award-number":["7200AA18C00070"]}],"id":[{"id":"10.13039\/100000200","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Maternal &amp; Child Nutrition"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Anaemia among women and young children remains a major public health concern. This secondary study describes the anaemia prevalence among young hospitalised children and their mothers in northern Lao People's Democratic Republic and explores possible nutritional causes and risk factors for anaemia. Hospitalised children (ages 21 days to &lt;18 months) with clinical symptoms suggestive of thiamine deficiency disorders were eligible along with their mothers. Venous blood was collected for determination of haemoglobin, ferritin, soluble transferrin receptor (sTfR), retinol\u2010binding protein (RBP), erythrocyte glutathione reductase activation coefficient (EGRac), thiamine diphosphate (ThDP) and acute phase proteins. Risk factors for anaemia were modelled using minimally adjusted logistic regression controlling for age. Haemoglobin results were available for 436 women (mean\u2009\u00b1\u2009SD age 24.7\u2009\u00b1\u20096.4 years; 1.6% pregnant) and 427 children (4.3\u2009\u00b1\u20093.5 months; 60.3% male). Anaemia prevalence (Hb\u2009&lt;\u2009120\u2009g\/L for nonpregnant women and &lt;110\u2009g\/L for pregnant women and children) was 30.7% among women and 55.2% among children. In bivariate analyses, biomarkers significantly associated with anaemia in women were ferritin, sTfR, RBP, EGRac\u00a0and ThDP. Other risk factors for women were lower BMI, mid\u2010upper arm circumference\u2009&lt;\u200923.5\u2009cm, lower education, lower socioeconomic index, food insecurity, Hmong ethnicity, not\/rarely having attended antenatal care, not having taken antenatal iron\u2010containing supplements and not meeting minimum dietary diversity. Risk factors for anaemia among children were older age, male sex, stunting, sTfR, ThDP\u00a0and alpha\u20101\u2010acid\u2010glycoprotein. Anaemia was common among women and their hospitalised children and was associated with micronutrient deficiencies and socioeconomic,\u00a0dietary and health care\u2010seeking risk factors, suggesting that multiple strategies are required to prevent anaemia among women and children.<\/jats:p>","DOI":"10.1111\/mcn.13565","type":"journal-article","created":{"date-parts":[[2023,10,8]],"date-time":"2023-10-08T18:30:19Z","timestamp":1696789819000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Risk factors for anaemia among women and their young children hospitalised with suspected thiamine deficiency in northern Lao PDR"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4661-277X","authenticated-orcid":false,"given":"Sonja Y.","family":"Hess","sequence":"first","affiliation":[{"name":"Institute for Global Nutrition and Department of Nutrition University of California Davis  Davis California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9543-6461","authenticated-orcid":false,"given":"Taryn J.","family":"Smith","sequence":"additional","affiliation":[{"name":"Institute for Global Nutrition and Department of Nutrition University of California Davis  Davis California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dalaphone","family":"Sitthideth","sequence":"additional","affiliation":[{"name":"Lao Tropical and Public Health Institute  Vientiane Lao People's Democratic Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles D.","family":"Arnold","sequence":"additional","affiliation":[{"name":"Institute for Global Nutrition and Department of Nutrition University of California Davis  Davis California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiuping","family":"Tan","sequence":"additional","affiliation":[{"name":"Institute for Global Nutrition and Department of Nutrition University of California Davis  Davis California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerry S.","family":"Jones","sequence":"additional","affiliation":[{"name":"Nutritional Biomarker Laboratory, MRC Epidemiology Unit University of Cambridge  Cambridge UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth H.","family":"Brown","sequence":"additional","affiliation":[{"name":"Institute for Global Nutrition and Department of Nutrition University of California Davis  Davis California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8023-5023","authenticated-orcid":false,"given":"Silvia","family":"Alayon","sequence":"additional","affiliation":[{"name":"USAID Advancing Nutrition  Arlington Virginia USA"},{"name":"Save the Children  Washington Washington, D.C. USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sengchanh","family":"Kounnavong","sequence":"additional","affiliation":[{"name":"Lao Tropical and Public Health Institute  Vientiane Lao People's Democratic Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,10,6]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/nutrit\/nuac043"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2018.11.022"},{"key":"e_1_2_9_4_1","volume-title":"Guide to anthropometry: A practical tool for program planners, managers, and implementers","author":"Cashin K.","year":"2018"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/nyas.14092"},{"key":"e_1_2_9_6_1","volume-title":"Household Food Insecurity Access Scale (HFIAS) for Measurement of Household Food Access: Indicator Guide (v. 3)","author":"Coates J.","year":"2007"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.116.142323"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/134.11.3127"},{"key":"e_1_2_9_9_1","volume-title":"Minimum dietary diversity for women: A guide for measurement","author":"FAO & FHI 360","year":"2016"},{"key":"e_1_2_9_10_1","volume-title":"Williams Hematology, 10th Edition","author":"Green R.","year":"2021"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/nyas.14985"},{"key":"e_1_2_9_12_1","unstructured":"Hess S. Y. Smith T. J. &Arnold C. D.(2022).Lao Thiamine Study. 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Appendix Q: Methods of blood and urinary analysis and quality control (QC) and quality assessment (QA).https:\/\/www.gov.uk\/government\/statistics\/ndns-results-from-years-9-to-11-2016-to-2017-and-2018-to-2019"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1177\/000456328201900111"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/nyas.14536"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1017\/jns.2022.94"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/mcn.13273"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(22)00084-5"},{"key":"e_1_2_9_29_1","volume-title":"Use of cutoffs for mid\u2010upper arm circumference (MUAC) as an indicator or predictor of nutritional and health\u2010related outcomes in adolescents and adults: A systematic review","author":"Tang A. 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