{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T23:43:28Z","timestamp":1782258208746,"version":"3.54.5"},"reference-count":52,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,6,17]],"date-time":"2024-06-17T00:00:00Z","timestamp":1718582400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012336","name":"Major State Basic Research Development Program of China","doi-asserted-by":"publisher","award":["2012CB525001"],"award-info":[{"award-number":["2012CB525001"]}],"id":[{"id":"10.13039\/501100012336","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Maternal &amp; Child Nutrition"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Iodine, an essential trace element for the human body, plays a pivotal role in sustaining health. Malnutrition has emerged as a pressing public health concern, posing a significant threat to human well\u2010being. Iodine deficiency poses a substantial threat to the development of children, potentially leading to neurological developmental disorders and mental retardation. Conversely, excessive iodine intake can result in structural and functional abnormalities in the thyroid gland. In this study, we selected children aged 3\u20136 years through a stratified cluster sampling approach in six regions across China to explore the correlation between iodine nutrition and their physical growth. A total of 5920 preschool children participated in this study, with a median urinary iodine concentration (UIC) of 177.33 [107.06, 269.92]\u2009\u03bcg\/L. Among these children, 250 (4.2%) exhibited stunting, 180 (3.0%) were underweight, 198 (3.3%) experienced wasting, 787 (3.3%) were overweight and 414 (7.0%) were classified as obese. The multivariate linear regression revealed that UIC exhibited a positive correlation with body mass index <jats:italic>z<\/jats:italic>\u2010Score (BMIZ) in overweight children (<jats:italic>\u03b2<\/jats:italic>\u2009=\u20090.038; 95% CI: 0.001, 0.075). In normally growing children, the associations between UIC and height\u2010for\u2010age <jats:italic>z<\/jats:italic>\u2010score, weight\u2010for\u2010age <jats:italic>z<\/jats:italic>\u2010score and BMIZ displayed nonlinear patterns. Our findings suggest that iodine nutrition is adequate for Chinese children aged 3\u20136 years. Furthermore, iodine nutrition is intricately linked to the growth and development of these children. Consequently, it is imperative to implement decisive measures to prevent both iodine deficiency and excess.<\/jats:p>","DOI":"10.1111\/mcn.13685","type":"journal-article","created":{"date-parts":[[2024,6,18]],"date-time":"2024-06-18T02:19:22Z","timestamp":1718677162000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["A national survey of iodine nutrition in children aged 3\u20136 years in China and its relationship with children's physical growth"],"prefix":"10.1111","volume":"20","author":[{"given":"Jing","family":"Li","sequence":"first","affiliation":[{"name":"MOE\u2010Shanghai Key Laboratory of Children's Environmental Health School of Public Health, Shanghai Jiao Tong University School of Medicine Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun\u2010Xia","family":"Liu","sequence":"additional","affiliation":[{"name":"MOE\u2010Shanghai Key Laboratory of Children's Environmental Health Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao\u2010Li","family":"Shen","sequence":"additional","affiliation":[{"name":"MOE\u2010Shanghai Key Laboratory of Children's Environmental Health School of Public Health, Shanghai Jiao Tong University School of Medicine Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu\u2010Qing","family":"Wang","sequence":"additional","affiliation":[{"name":"MOE\u2010Shanghai Key Laboratory of Children's Environmental Health School of Public Health, Shanghai Jiao Tong University School of Medicine Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3096-7098","authenticated-orcid":false,"given":"Chong\u2010Huai","family":"Yan","sequence":"additional","affiliation":[{"name":"MOE\u2010Shanghai Key Laboratory of Children's Environmental Health Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,6,17]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)32129-3"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu15061536"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1172\/jci29812"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)60937-X"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2015.0448"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu12041077"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.3967\/bes2016.051"},{"key":"e_1_2_10_9_1","unstructured":"China(CHN)\u2010Demographics. (2021).Health & infant mortality\u2014UNICEF DATA. Retrieved 28 June fromhttps:\/\/data.unicef.org\/country\/chn\/"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2020.0189"},{"issue":"3","key":"e_1_2_10_11_1","first-page":"317","article-title":"Iodine deficiency disorders in Europe","volume":"67","author":"Delange F.","year":"1989","journal-title":"Bulletin of the World Health Organization"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAT.0b013e32834e8e83"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/nyas.14041"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgab919"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.5603\/ep.2018.0032"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu13113975"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu14173474"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2023.164628"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfma.2023.02.010"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu8040172"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00394-013-0558-y"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2019.0067"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2020.3386"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41574-019-0218-2"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms241512074"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2020.0582"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.2471\/blt.07.043497"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/s2213-8587(21)00045-0"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu13051404"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2015.0613"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41366-018-0129-7"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1159\/000182580"},{"key":"e_1_2_10_33_1","unstructured":"The Comprehensive R Archive. (n.d.).CRAN \u2010 Package anthroplus.https:\/\/cran.r-project.org\/web\/packages\/anthroplus\/index.html"},{"key":"e_1_2_10_34_1","unstructured":"The Comprehensive R Archive Network. (n.d.).CRAN \u2010 Package anthro.https:\/\/cran.r-project.org\/web\/packages\/anthro\/index.html"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1530\/joe-15-0133"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.2307\/3343436"},{"key":"e_1_2_10_37_1","unstructured":"World Health Organization. (n.d.).WHO Anthro Survey Analyser and other tools.https:\/\/www.who.int\/tools\/child-growth-standards\/software."},{"key":"e_1_2_10_38_1","unstructured":"World Health Organization. (2007).Assessment of iodine deficiency disorders and monitoring their elimination: A guide for programme managers(3rd ed.). Retrieved 1 September fromhttps:\/\/www.who.int\/publications\/i\/item\/9789241595827"},{"key":"e_1_2_10_39_1","unstructured":"World Health Organization. (2012). Retrieved 8 August fromhttps:\/\/www.who.int\/zh\/news-room\/fact-sheets\/detail\/malnutrition"},{"key":"e_1_2_10_40_1","unstructured":"World Health Organization. (2023).WHO child growth standards: Methods and development. Retrieved 8 August fromhttps:\/\/www.who.int\/publications\/i\/item\/924154693X"},{"key":"e_1_2_10_41_1","unstructured":"World Health Organization. (2024).Obesity and overweight. Retrieved 1 March fromhttps:\/\/www.who.int\/zh\/news-room\/fact-sheets\/detail\/obesity-and-overweight"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12020-023-03413-8"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17041129"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2022.985786"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.3967\/bes2016.021"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0245455"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-019-6515-9"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1530\/eje-21-0171"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-323-66162-1.00025-1"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.3945\/jn.115.229005"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)61005-3"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12519-023-00747-1"},{"key":"e_1_2_10_53_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2014-005484"}],"container-title":["Maternal &amp; Child Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/mcn.13685","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T11:52:46Z","timestamp":1732017166000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/mcn.13685"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,17]]},"references-count":52,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["10.1111\/mcn.13685"],"URL":"https:\/\/doi.org\/10.1111\/mcn.13685","archive":["Portico"],"relation":{},"ISSN":["1740-8695","1740-8709"],"issn-type":[{"value":"1740-8695","type":"print"},{"value":"1740-8709","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,17]]},"assertion":[{"value":"2024-01-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e13685"}}