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For example, closely related strains of beneficial rhizosphere\n Pseudomonas<\/jats:italic>\n spp. can induce systemic resistance (\n ISR<\/jats:styled-content>\n ), systemic susceptibility (\n ISS<\/jats:styled-content>\n ) or neither against the bacterial foliar pathogen\n Pseudomonas syringae<\/jats:italic>\n pv. tomato\n DC<\/jats:styled-content>\n 3000 (\n Pto<\/jats:italic>\n DC<\/jats:styled-content>\n 3000). Using a model system composed of root\u2010associated\n Pseudomonas<\/jats:italic>\n spp. strains, the foliar pathogen\n Pto<\/jats:italic>\n DC<\/jats:styled-content>\n 3000 and the herbivore\n Trichoplusia ni<\/jats:italic>\n (cabbage looper), we found that rhizosphere\u2010associated\n Pseudomonas<\/jats:italic>\n spp. that induce either\n ISS<\/jats:styled-content>\n and\n ISR<\/jats:styled-content>\n against\n Pto<\/jats:italic>\n DC<\/jats:styled-content>\n 3000 all increased resistance to herbivory by\n T.\u00a0ni<\/jats:italic>\n . We found that resistance to\n T.\u00a0ni<\/jats:italic>\n and resistance to\n Pto<\/jats:italic>\n DC<\/jats:styled-content>\n 3000 are quantitative metrics of the jasmonic acid (\n JA<\/jats:styled-content>\n )\/salicylic acid (\n SA<\/jats:styled-content>\n ) trade\u2010off and distinct strains of rhizosphere\u2010associated\n Pseudomonas<\/jats:italic>\n spp. have distinct effects on the\n JA<\/jats:styled-content>\n \/\n SA<\/jats:styled-content>\n trade\u2010off. Using genetic analysis and transcriptional profiling, we provide evidence that treatment of\n Arabidopsis<\/jats:italic>\n with\n Pseudomonas<\/jats:italic>\n sp.\n CH<\/jats:styled-content>\n 267, which induces\n ISS<\/jats:styled-content>\n against bacterial pathogens, tips the\n JA<\/jats:styled-content>\n \/\n SA<\/jats:styled-content>\n trade\u2010off towards\n JA<\/jats:styled-content>\n \u2010dependent defences against herbivores at the cost of a subset of\n SA<\/jats:styled-content>\n \u2010mediated defences against bacterial pathogens. In contrast, treatment of\n Arabidopsis<\/jats:italic>\n with the\n ISR<\/jats:styled-content>\n strain\n Pseudomonas<\/jats:italic>\n sp.\n \n WCS<\/jats:styled-content>\n 417\n <\/jats:italic>\n disrupts\n JA<\/jats:styled-content>\n \/\n SA<\/jats:styled-content>\n antagonism and simultaneously primes plants for both\n JA<\/jats:styled-content>\n \u2010 and\n SA<\/jats:styled-content>\n \u2010mediated defences. Our findings show that\n ISS<\/jats:styled-content>\n against the bacterial foliar pathogens triggered by\n Pseudomonas<\/jats:italic>\n sp.\n CH<\/jats:styled-content>\n 267\n ,<\/jats:italic>\n which is a seemingly deleterious phenotype, may in fact be an adaptive consequence of increased resistance to herbivory. Our work shows that pleiotropic effects of microbiome modulation of plant defences are important to consider when using microbes to modify plant traits in agriculture.\n <\/jats:p>","DOI":"10.1111\/mec.14400","type":"journal-article","created":{"date-parts":[[2017,10,31]],"date-time":"2017-10-31T05:32:34Z","timestamp":1509427954000},"page":"1833-1847","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":80,"title":["Rhizosphere\u2010associated\n Pseudomonas<\/i>\n induce systemic resistance to herbivores at the cost of susceptibility to bacterial pathogens"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6099-6677","authenticated-orcid":false,"given":"Cara H.","family":"Haney","sequence":"first","affiliation":[{"name":"Department of Microbiology and Immunology The University of British Columbia Vancouver BC Canada"},{"name":"Michael Smith Laboratories The University of British Columbia Vancouver 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