{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T14:22:17Z","timestamp":1791987737030,"version":"4.4.0"},"reference-count":79,"publisher":"Wiley","issue":"18","license":[{"start":{"date-parts":[[2020,8,15]],"date-time":"2020-08-15T00:00:00Z","timestamp":1597449600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Molecular Ecology"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Understanding the origin of new species is a central goal in evolutionary biology. Diverging lineages often evolve highly heterogeneous patterns of genetic differentiation; however, the underlying mechanisms are not well understood. We investigated evolutionary processes governing genetic differentiation between the hybridizing campions <jats:italic>Silene dioica<\/jats:italic> (L.) Clairv. and <jats:italic>S. latifolia<\/jats:italic> Poiret. Demographic modelling indicated that the two species diverged with gene flow. The best\u2010supported scenario with heterogeneity in both migration rate and effective population size suggested that a small proportion of the loci evolved without gene flow. Differentiation (<jats:italic>F<\/jats:italic>\n<jats:sub>ST<\/jats:sub>) and sequence divergence (<jats:italic>d<\/jats:italic>\n<jats:sub>XY<\/jats:sub>) were correlated and both tended to peak in the middle of most linkage groups, consistent with reduced gene flow at highly differentiated loci. Highly differentiated loci further exhibited signatures of selection. In between\u2010species population pairs, isolation by distance was stronger for genomic regions with low between\u2010species differentiation than for highly differentiated regions that may contain barrier loci. Moreover, differentiation landscapes within and between species were only weakly correlated, suggesting that linked selection due to shared recombination and gene density landscapes is not the dominant determinant of genetic differentiation in these lineages. Instead, our results suggest that divergent selection shaped the genomic landscape of differentiation between the two <jats:italic>Silene<\/jats:italic> species, consistent with predictions for speciation in the face of gene flow.<\/jats:p>","DOI":"10.1111\/mec.15571","type":"journal-article","created":{"date-parts":[[2020,8,2]],"date-time":"2020-08-02T20:29:32Z","timestamp":1596400172000},"page":"3511-3525","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Evolution of putative barrier loci at an intermediate stage of speciation with gene flow in campions (<i>Silene<\/i>)"],"prefix":"10.1111","volume":"29","author":[{"given":"Xiaodong","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Ecology and Genetics Evolutionary Biology Centre Uppsala University  Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvain","family":"Gl\u00e9min","sequence":"additional","affiliation":[{"name":"Department of Ecology and Genetics Evolutionary Biology Centre Uppsala University  Uppsala Sweden"},{"name":"UMR CNRS 6553 ECOBIO Universit\u00e9 de Rennes I  Rennes Cedex France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7146-588X","authenticated-orcid":false,"given":"Sophie","family":"Karrenberg","sequence":"additional","affiliation":[{"name":"Department of Ecology and Genetics Evolutionary Biology Centre Uppsala University  Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,8,15]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1101\/gr.094052.109"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/mec.14373"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btu170"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/evl3.14"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1101\/gr.196485.115"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1086\/695136"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/mec.12354"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrg2526"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bts482"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/mec.13765"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/01621459.1979.10481038"},{"key":"e_1_2_9_13_1","first-page":"545","volume-title":"Speciation","author":"Coyne J. A.","year":"2004"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/mec.12796"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btr330"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/evl3.46"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-04963-6"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/nph.14202"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1004966"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/mec.12750"},{"key":"e_1_2_9_21_1","volume-title":"Illustrierte Flora von Mitteleuropa","author":"Friedrich H. C.","year":"1979"},{"key":"e_1_2_9_22_1","volume-title":"Vcflib: A C++ library for parsing and manipulating VCF files","author":"Garrison E.","year":"2012"},{"key":"e_1_2_9_23_1","unstructured":"Garrison E. &Marth G.(2012).Haplotype\u2010based variant detection from short\u2010read sequencing.arXiv:1207.3907"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-8286.2004.00828.x"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.2307\/3546096"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/mec.13969"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1000695"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/mec.14699"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1101\/gr.212522.116"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1095-8339.2009.01003.x"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1038\/35016000"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1198\/000313006X118430"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/mec.13427"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/mec.14858"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btn129"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1558-5646.2008.00330.x"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/evo.13652"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2018.04.069"},{"key":"e_1_2_9_39_1","unstructured":"Li H.(2013).Aligning sequence reads clone sequences and assembly contigs with BWA\u2010MEM. arXiv:1303.3997"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1111\/mec.14562"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aac9927"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/mec.13774"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1101\/gr.159426.113"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/mec.12591"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msy051"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-294X.2007.03292.x"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1558-5646.2011.01529.x"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2011.0249"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-294X.2006.02908.x"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.genet.39.073003.112420"},{"key":"e_1_2_9_51_1","unstructured":"Oksanen J. Blanchet F. G. Friendly M. Kindt R. Legendre P. McGlinn D. Wagner H.(2019).vegan:Community Ecology Package. R package version 2.5\u20105. Retrieved from:https:\/\/CRAN.R\u2010project.org\/package=vegan"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1111\/mec.14792"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.1002379"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0037135"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00606-007-0629-8"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1086\/519795"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.431"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1111\/evo.12957"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ympev.2010.08.003"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1111\/jeb.13047"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1007358"},{"key":"e_1_2_9_62_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms2833"},{"key":"e_1_2_9_63_1","doi-asserted-by":"publisher","DOI":"10.1002\/bies.201900047"},{"key":"e_1_2_9_64_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41559-017-0082"},{"key":"e_1_2_9_65_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1558-5646.2011.01486.x"},{"key":"e_1_2_9_66_1","doi-asserted-by":"publisher","DOI":"10.1111\/evo.13486"},{"key":"e_1_2_9_67_1","doi-asserted-by":"publisher","DOI":"10.1111\/jeb.12425"},{"key":"e_1_2_9_68_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.2000234"},{"key":"e_1_2_9_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tree.2009.02.007"},{"key":"e_1_2_9_70_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1558-5646.2011.01537.x"},{"key":"e_1_2_9_71_1","doi-asserted-by":"publisher","DOI":"10.1111\/mec.14226"},{"key":"e_1_2_9_72_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrg3644"},{"key":"e_1_2_9_73_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.3000391"},{"key":"e_1_2_9_74_1","doi-asserted-by":"publisher","DOI":"10.1093\/genetics\/110.2.325"},{"key":"e_1_2_9_75_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms6770"},{"key":"e_1_2_9_76_1","doi-asserted-by":"publisher","DOI":"10.1111\/mec.14195"},{"key":"e_1_2_9_77_1","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msw051"},{"key":"e_1_2_9_78_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrg.2016.133"},{"key":"e_1_2_9_79_1","doi-asserted-by":"publisher","DOI":"10.1086\/682405"},{"key":"e_1_2_9_80_1","doi-asserted-by":"publisher","DOI":"10.1111\/mec.13611"}],"container-title":["Molecular Ecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fmec.15571","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/mec.15571","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/mec.15571","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/mec.15571","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,3]],"date-time":"2023-09-03T07:36:45Z","timestamp":1693726605000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/mec.15571"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,15]]},"references-count":79,"journal-issue":{"issue":"18","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["10.1111\/mec.15571"],"URL":"https:\/\/doi.org\/10.1111\/mec.15571","archive":["Portico"],"relation":{},"ISSN":["0962-1083","1365-294X"],"issn-type":[{"value":"0962-1083","type":"print"},{"value":"1365-294X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,15]]},"assertion":[{"value":"2019-07-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-07-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-08-15","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}