{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T14:42:34Z","timestamp":1790779354817,"version":"4.1.0"},"reference-count":56,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2021,3,22]],"date-time":"2021-03-22T00:00:00Z","timestamp":1616371200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004919","name":"King Abdulaziz City for Science and Technology","doi-asserted-by":"publisher","award":["KACST\u2010NSTIP\u201012\u2010AGR\u20102854\u201002"],"award-info":[{"award-number":["KACST\u2010NSTIP\u201012\u2010AGR\u20102854\u201002"]}],"id":[{"id":"10.13039\/501100004919","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004052","name":"King Abdullah University of Science and Technology","doi-asserted-by":"publisher","award":["KAUST\u2010OSR\u20102018\u2010RPW\u20103816"],"award-info":[{"award-number":["KAUST\u2010OSR\u20102018\u2010RPW\u20103816"]}],"id":[{"id":"10.13039\/501100004052","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Molecular Ecology"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Palm trees are of immense economic, sociocultural, touristic, and patrimonial significance all over the world, and date palm\u2010related knowledge, traditions, and practices are now included in UNESCOs list of the Intangible Cultural Heritage of Humanity. Of all the pests that infest these trees, the red palm weevil (RPW),\n                    <jats:italic>Rhynchophorus ferrugineus<\/jats:italic>\n                    (Olivier), is its primary enemy. The RPW is a category\u20101 quarantine insect pest that causes enormous economic losses in palm tree cultivation worldwide. The RPW synchronizes mass gathering on the palm tree for feeding and mating, regulated by a male\u2010produced pheromone composed of two methyl\u2010branched compounds, (4\n                    <jats:italic>RS<\/jats:italic>\n                    , 5\n                    <jats:italic>RS<\/jats:italic>\n                    )\u20104\u2010methylnonan\u20105\u2010ol (ferrugineol) and 4(\n                    <jats:italic>RS<\/jats:italic>\n                    )\u2010methylnonan\u20105\u2010one (ferrugineone). Despite the importance of odorant detection in long\u2010range orientation towards palm trees, palm colonization, and mating, the pheromone receptor has not been identified in this species. In this study, we report the identification and characterization of the first RPW pheromone receptor,\n                    <jats:italic>RferOR1<\/jats:italic>\n                    . Using gene silencing and functional expression in\n                    <jats:italic>Drosophila<\/jats:italic>\n                    olfactory receptor neurons, we demonstrate that\n                    <jats:italic>RferOR1<\/jats:italic>\n                    is tuned to ferrugineol and ferrugineone and binds five other structurally related molecules. We reveal the lifetime expression of\n                    <jats:italic>RferOR1<\/jats:italic>\n                    , which correlates with adult mating success irrespective of age, a factor that could explain the wide distribution and spread of this pest. As palm weevils are challenging to control based on conventional methods, elucidation of the mechanisms of pheromone detection opens new routes for mating disruption and the early detection of this pest via the development of pheromone receptor\u2010based biosensors.\n                  <\/jats:p>","DOI":"10.1111\/mec.15874","type":"journal-article","created":{"date-parts":[[2021,3,9]],"date-time":"2021-03-09T10:39:07Z","timestamp":1615286347000},"page":"2025-2039","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":66,"title":["Pheromone receptor of the globally invasive quarantine pest of the palm tree, the red palm weevil (\n                    <i>Rhynchophorus ferrugineus<\/i>\n                    )"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6292-620X","authenticated-orcid":false,"given":"Binu","family":"Antony","sequence":"first","affiliation":[{"name":"Department of Plant Protection College of Food and Agricultural Sciences Center for Chemical Ecology and Functional Genomics Chair of Date Palm Research King Saud University Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2265-5046","authenticated-orcid":false,"given":"Jibin","family":"Johny","sequence":"additional","affiliation":[{"name":"Department of Plant Protection College of Food and Agricultural Sciences Center for Chemical Ecology and Functional Genomics Chair of Date Palm Research King Saud University Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8810-3853","authenticated-orcid":false,"given":"Nicolas","family":"Montagn\u00e9","sequence":"additional","affiliation":[{"name":"INRAE Sorbonne Universit\u00e9 CNRS IRD UPEC Institute of Ecology and Environmental Sciences of Paris iEES\u2010Paris Universit\u00e9 Paris Diderot Versailles France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6904-2036","authenticated-orcid":false,"given":"Emmanuelle","family":"Jacquin\u2010Joly","sequence":"additional","affiliation":[{"name":"INRAE Sorbonne Universit\u00e9 CNRS IRD UPEC Institute of Ecology and Environmental Sciences of Paris iEES\u2010Paris Universit\u00e9 Paris Diderot Versailles France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R\u00e9mi","family":"Capoduro","sequence":"additional","affiliation":[{"name":"INRAE Sorbonne Universit\u00e9 CNRS IRD UPEC Institute of Ecology and Environmental Sciences of Paris iEES\u2010Paris Universit\u00e9 Paris Diderot Versailles France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2017-6922","authenticated-orcid":false,"given":"Khasim","family":"Cali","sequence":"additional","affiliation":[{"name":"Department of Chemical Engineering and Analytical Science The University of Manchester Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5730-9568","authenticated-orcid":false,"given":"Krishna","family":"Persaud","sequence":"additional","affiliation":[{"name":"Department of Chemical Engineering and Analytical Science The University of Manchester Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed Ali","family":"Al\u2010Saleh","sequence":"additional","affiliation":[{"name":"Department of Plant Protection College of Food and Agricultural Sciences Center for Chemical Ecology and Functional Genomics Chair of Date Palm Research King Saud University Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1755-2819","authenticated-orcid":false,"given":"Arnab","family":"Pain","sequence":"additional","affiliation":[{"name":"BESE Division King Abdullah University of Science and Technology (KAUST) Jeddah Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,3,22]]},"reference":[{"issue":"4","key":"e_1_2_9_2_1","first-page":"520","article-title":"Impact of mating frequency on fecundity, fertility and longevity of red palm weevil, Rhynchophorus ferrugineus (Olivier)(Coleoptera: Curuclionidae)","volume":"2","author":"Abdel\u2010Azim M. 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