{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T22:09:30Z","timestamp":1791497370661,"version":"4.3.4"},"reference-count":65,"publisher":"Wiley","issue":"21","license":[{"start":{"date-parts":[[2022,9,10]],"date-time":"2022-09-10T00:00:00Z","timestamp":1662768000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010663","name":"H2020 European Research Council","doi-asserted-by":"publisher","award":["695225"],"award-info":[{"award-number":["695225"]}],"id":[{"id":"10.13039\/100010663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Molecular Ecology"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The guppy Y chromosome has been considered a model system for the evolution of suppressed recombination between sex chromosomes, and it has been proposed that complete sex\u2010linkage has evolved across about 3\u00a0Mb surrounding this fish's sex\u2010determining locus, followed by recombination suppression across a further 7\u00a0Mb of the 23\u2009Mb XY pair, forming younger \u201cevolutionary strata\u201d. Sequences of the guppy genome show that Y is very similar to the X chromosome. Knowing which parts of the Y are completely nonrecombining, and whether there is indeed a large completely nonrecombining region, are important for understanding its evolution. Here, we describe analyses of PoolSeq data in samples from within multiple natural populations from Trinidad, yielding new results that support previous evidence for occasional recombination between the guppy Y and X. We detected recent demographic changes, notably that downstream populations have higher synonymous site diversity than upstream ones and other expected signals of bottlenecks. We detected evidence of associations between sequence variants and the sex\u2010determining locus, rather than divergence under a complete lack of recombination. Although recombination is infrequent, it is frequent enough that associations with SNPs can suggest the region in which the sex\u2010determining locus must be located. Diversity is elevated across a physically large region of the sex chromosome, conforming to predictions for a genome region with infrequent recombination that carries one or more sexually antagonistic polymorphisms. However, no consistently male\u2010specific variants were found, supporting the suggestion that any completely sex\u2010linked region may be very small.<\/jats:p>","DOI":"10.1111\/mec.16674","type":"journal-article","created":{"date-parts":[[2022,8,25]],"date-time":"2022-08-25T08:00:05Z","timestamp":1661414405000},"page":"5524-5537","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Partial sex linkage and linkage disequilibrium on the guppy sex chromosome"],"prefix":"10.1111","volume":"31","author":[{"given":"Suo","family":"Qiu","sequence":"first","affiliation":[{"name":"Institute of Evolutionary Biology, School of Biological Sciences University of Edinburgh  Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7459-4863","authenticated-orcid":false,"given":"Lengxob","family":"Yong","sequence":"additional","affiliation":[{"name":"Centre for Ecology and Conservation, College of Life and Environmental Sciences University of Exeter  Penryn UK"},{"name":"Marine Resources Research Institute South Carolina Department of Natural Resources  Charleston South Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5045-2051","authenticated-orcid":false,"given":"Alastair","family":"Wilson","sequence":"additional","affiliation":[{"name":"Centre for Ecology and Conservation, College of Life and Environmental Sciences University of Exeter  Penryn UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darren P.","family":"Croft","sequence":"additional","affiliation":[{"name":"Centre for Research in Animal Behaviour, College of Life and Environmental Sciences University of Exeter  Exeter UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chay","family":"Graham","sequence":"additional","affiliation":[{"name":"Institute of Evolutionary Biology, School of Biological Sciences University of Edinburgh  Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3939-9122","authenticated-orcid":false,"given":"Deborah","family":"Charlesworth","sequence":"additional","affiliation":[{"name":"Institute of Evolutionary Biology, School of Biological Sciences University of Edinburgh  Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,9,10]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msaa257"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1420\u20109101.2008.01675.x"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1818486116"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1009082"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.molbev.a025953"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0016672397002954"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/nph.16002"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1009704"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1534\/g3.120.401573"},{"key":"e_1_2_11_11_1","volume-title":"Elements of evolutionary genetics","author":"Charlesworth D.","year":"2010"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature13151"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/mec.12796"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2021.0205"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/gbe\/evaa099"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1905298116"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1534\/g3.119.400656"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1558-5646.1980.tb04790.x"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/hdy.1981.79"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/jeb.12251"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/mec.13022"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/gbe\/evaa187"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1558\u20105646.2011.01495.x"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1086\/689864"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1101\/gr.3541005"},{"key":"e_1_2_11_26_1","first-page":"320","volume-title":"Vertebrate speciation","author":"Haskins C.","year":"1961"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1534\/genetics.118.300900"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/hdy.1992.120"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature12717"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1002798"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1534\/genetics.109.113555"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1534\/genetics.113.156026"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0015925"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2019.04.069"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.286.5441.964"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1093\/genetics\/162.1.501"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btp698"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btp352"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1086\/342898"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.hdy.6800386"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.1089\/zeb.2014.1000"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.1093\/acprof:oso\/9780198527855.001.0001"},{"key":"e_1_2_11_43_1","doi-asserted-by":"crossref","unstructured":"Manuel M. Wu F. L. &Przeworski M.(2022).A paternal bias in germline mutation is widespread across amniotes and can arise independently of cell divisions.bioRxiv.https:\/\/doi.org\/10.1101\/2022.02.07.479417","DOI":"10.1101\/2022.02.07.479417"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00412\u2010014\u20100455\u2010z"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btv449"},{"key":"e_1_2_11_46_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature04646"},{"key":"e_1_2_11_47_1","doi-asserted-by":"publisher","DOI":"10.1111\/nph.16083"},{"key":"e_1_2_11_48_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1508454112"},{"key":"e_1_2_11_49_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010019\u201047832\u2010y"},{"key":"e_1_2_11_50_1","doi-asserted-by":"publisher","DOI":"10.1186\/gb\u20102009\u201010\u20102\u2010r16"},{"key":"e_1_2_11_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2015.10.071"},{"key":"e_1_2_11_52_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1558-5646.1987.tb05864.x"},{"key":"e_1_2_11_53_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41559\u2010021\u201001452\u2010w"},{"key":"e_1_2_11_54_1","doi-asserted-by":"publisher","DOI":"10.1086\/704943"},{"key":"e_1_2_11_55_1","first-page":"8","article-title":"The genetic behavlour of a secondary sexual character","volume":"14","author":"Schmidt J.","year":"1920","journal-title":"Comptes\u2010rendus des travails du Laborotoire Carlsberg"},{"key":"e_1_2_11_56_1","doi-asserted-by":"publisher","DOI":"10.1093\/nargab\/lqab019"},{"key":"e_1_2_11_57_1","doi-asserted-by":"publisher","DOI":"10.1038\/hdy.2009.7"},{"key":"e_1_2_11_58_1","doi-asserted-by":"publisher","DOI":"10.1093\/genetics\/123.3.585"},{"key":"e_1_2_11_59_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1012956324417"},{"key":"e_1_2_11_60_1","doi-asserted-by":"publisher","DOI":"10.1534\/genetics.108.098541"},{"key":"e_1_2_11_61_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1009566"},{"key":"e_1_2_11_62_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u2010294X.2010.04528.x"},{"key":"e_1_2_11_63_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02983077"},{"key":"e_1_2_11_64_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms14251"},{"key":"e_1_2_11_65_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41559\u2010019\u20100850\u20101"},{"key":"e_1_2_11_66_1","doi-asserted-by":"publisher","DOI":"10.1111\/mec.16039"}],"container-title":["Molecular Ecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/mec.16674","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/mec.16674","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/mec.16674","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T07:04:01Z","timestamp":1692601441000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/mec.16674"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,10]]},"references-count":65,"journal-issue":{"issue":"21","published-print":{"date-parts":[[2022,11]]}},"alternative-id":["10.1111\/mec.16674"],"URL":"https:\/\/doi.org\/10.1111\/mec.16674","archive":["Portico"],"relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2022.01.14.476360","asserted-by":"object"}]},"ISSN":["0962-1083","1365-294X"],"issn-type":[{"value":"0962-1083","type":"print"},{"value":"1365-294X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,10]]},"assertion":[{"value":"2022-03-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-08-09","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-09-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}