{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T03:32:38Z","timestamp":1787801558904,"version":"build-2784847793"},"reference-count":34,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2022,10,4]],"date-time":"2022-10-04T00:00:00Z","timestamp":1664841600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","award":["CUPS2"],"award-info":[{"award-number":["CUPS2"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002915","name":"Fondation pour la Recherche M\u00e9dicale","doi-asserted-by":"publisher","award":["to Tsukushi Kamiya"],"award-info":[{"award-number":["to Tsukushi Kamiya"]}],"id":[{"id":"10.13039\/501100002915","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010663","name":"H2020 European Research Council","doi-asserted-by":"publisher","award":["648963"],"award-info":[{"award-number":["648963"]}],"id":[{"id":"10.13039\/100010663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Molecular Ecology"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The vaginal ecosystem is a key component of women's health. It also represents an ideal system for ecologists to investigate the consequence of perturbations on species diversity and emerging properties between organizational levels. Here, we study how exposure to different types of menstrual products is linked to microbial, immunological, demographic, and behavioural measurements in a cohort of young adult women who reported using more often tampons (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a0107) or menstrual cups (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a031). We first found that cup users were older and smoked less than tampon users. When analysing health indicators, we detected potential associations between cups use reporting and fungal genital infection. A multivariate analysis confirmed that in our cohort, reporting using cups over tampons was associated with the higher odds ratio to report a fungal genital infection diagnosis by a medical doctor within the last 3\u00a0months. We did not detect significant differences between groups in terms of their bacterial vaginal microbiota composition and found marginal differences in the level of expression of 20 cytokines. However, a multivariate analysis of these biological data identified some level of clustering based on the menstrual product type preferred (cups or tampons). These results suggest that exposure to different types of menstrual products could influence menstrual health. Larger studies and studies with a more powered setting are needed to assess the robustness of these associations and identify causal mechanisms.\n                  <\/jats:p>","DOI":"10.1111\/mec.16678","type":"journal-article","created":{"date-parts":[[2022,9,4]],"date-time":"2022-09-04T01:18:56Z","timestamp":1662254336000},"page":"2592-2601","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Does exposure to different menstrual products affect the vaginal environment?"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7486-3445","authenticated-orcid":false,"given":"Nicolas","family":"Tessandier","sequence":"first","affiliation":[{"name":"Center for Interdisciplinary Research in Biology (CIRB) Coll\u00e8ge de France, CNRS, INSERM, Universit\u00e9 PSL  Paris France"},{"name":"MIVEGEC, CNRS, IRD Universit\u00e9 de Montpellier  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilkay Ba\u015fak","family":"Uysal","sequence":"additional","affiliation":[{"name":"MIVEGEC, CNRS, IRD Universit\u00e9 de Montpellier  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baptiste","family":"Elie","sequence":"additional","affiliation":[{"name":"MIVEGEC, CNRS, IRD Universit\u00e9 de Montpellier  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Selinger","sequence":"additional","affiliation":[{"name":"MIVEGEC, CNRS, IRD Universit\u00e9 de Montpellier  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Bernat","sequence":"additional","affiliation":[{"name":"MIVEGEC, CNRS, IRD Universit\u00e9 de Montpellier  Montpellier 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CNRS, IRD Universit\u00e9 de Montpellier  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noemi","family":"Bender","sequence":"additional","affiliation":[{"name":"Molecular Diagnostics of Oncogenic Infections, Infection, Inflammation and Cancer Program German Cancer Research Center (DKFZ)  Heidelberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marine","family":"Bonneau","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Centre Hospitalier Universitaire de Montpellier  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christelle","family":"Graf","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Centre Hospitalier Universitaire de Montpellier  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Tribout","sequence":"additional","affiliation":[{"name":"Center for Free Information, Screening and Diagnosis (CeGIDD) Centre Hospitalier Universitaire de Montpellier  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Foulongne","sequence":"additional","affiliation":[{"name":"Pathogenesis and Control of Chronic Infections INSERM, EFS, Montpellier University  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacques","family":"Ravel","sequence":"additional","affiliation":[{"name":"Institute for Genome Sciences, Department of Microbiology and Immunology University of Maryland School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"Waterboer","sequence":"additional","affiliation":[{"name":"Molecular Diagnostics of Oncogenic Infections, Infection, Inflammation and Cancer Program German Cancer Research Center (DKFZ)  Heidelberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Hirtz","sequence":"additional","affiliation":[{"name":"LBPC\/PPC\u2010 IRMB, CHU de Montpellier and Universit\u00e9 de Montpellier  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ignacio G.","family":"Bravo","sequence":"additional","affiliation":[{"name":"MIVEGEC, CNRS, IRD Universit\u00e9 de Montpellier  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacques","family":"Reynes","sequence":"additional","affiliation":[{"name":"Infectious Diseases Department, University Hospital Montpellier INSERM U1175\/Institut de Recherche et de Developement, Unit\u00e9 Mixte International  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Segondy","sequence":"additional","affiliation":[{"name":"Pathogenesis and Control of Chronic Infections University of Montpellier, INSERM, EFS, CHU Montpellier  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen Lia","family":"Murall","sequence":"additional","affiliation":[{"name":"Center for Interdisciplinary Research in Biology (CIRB) Coll\u00e8ge de France, CNRS, INSERM, Universit\u00e9 PSL  Paris France"},{"name":"MIVEGEC, CNRS, IRD Universit\u00e9 de Montpellier  Montpellier France"},{"name":"Department of Biological Sciences Universit\u00e9 de Montr\u00e9al  Montr\u00e9al Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Boulle","sequence":"additional","affiliation":[{"name":"Pathogenesis and Control of Chronic Infections, Departement of Pathology and Oncobiology, Laboratory of Solid Tumors, CHU Montpellier University of Montpellier, INSERM, EFS  Montpellier 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France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,10,4]]},"reference":[{"key":"e_1_2_10_2_1","first-page":"75","volume-title":"Model selection and inference: A practical information\u2010theoretic approach","author":"Burnham 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Ahannach S. Wittouck S. Gehrmann T. Eilers T. Oerlemans E. Condori S. Dillen J. Spacova I. Vander Donck L. Masquiller C. Bron P. Van Beeck W. De Backer C. Donders G. &Verhoeven V.(2022).Citizen\u2010science map of the vaginal microbiome. 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