{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T21:23:45Z","timestamp":1793741025491,"version":"4.6.1"},"reference-count":57,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010389","name":"American Society of Mammalogists","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010389","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012771","name":"Bell Museum of Natural History, University of Minnesota","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012771","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["2237827"],"award-info":[{"award-number":["2237827"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007249","name":"University of Minnesota","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007249","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011142","name":"Graduate School, University of Minnesota","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011142","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Molecular Ecology"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Rodents are key reservoirs of zoonotic pathogens and play an important role in disease transmission to humans. Importantly, anthropogenic land\u2010use change has been found to increase the abundance of rodents that thrive in human\u2010built environments (synanthropic rodents), particularly rodent reservoirs of zoonotic disease. Anthropogenic environments also affect the microbiome of synanthropic wildlife, influencing wildlife health and potentially introducing novel pathogens. Our objective was to examine the effect of agricultural development and synanthropic habitat on microbiome diversity and the prevalence of zoonotic bacterial pathogens in wild\n                    <jats:italic>Peromyscus<\/jats:italic>\n                    mice to better understand the role of these rodents in pathogen maintenance and transmission. We conducted 16S amplicon sequencing on faecal samples using long\u2010read nanopore sequencing technology to characterize the rodent microbiome. We compared microbiome diversity and composition between forest and synanthropic habitats in agricultural and undeveloped landscapes and screened for putative pathogenic bacteria. Microbiome richness, diversity, and evenness were higher in the agricultural landscape and synanthropic habitat compared to undeveloped\u2010forest habitat. Microbiome composition also differed significantly between agricultural and undeveloped landscapes and forest and synanthropic habitats. We detected overall low diversity and abundance of putative pathogenic bacteria, though putative pathogens were more likely to be found in mice from the agricultural landscape. Our findings show that landscape\u2010 and habitat\u2010level anthropogenic factors affect\n                    <jats:italic>Peromyscus<\/jats:italic>\n                    microbiomes and suggest that landscape\u2010level agricultural development may be important to predict zoonotic pathogen prevalence. Ultimately, understanding how anthropogenic land\u2010use change and synanthropy affect rodent microbiomes and pathogen prevalence is important to managing transmission of rodent\u2010borne zoonotic diseases to humans.\n                  <\/jats:p>","DOI":"10.1111\/mec.17309","type":"journal-article","created":{"date-parts":[[2024,3,2]],"date-time":"2024-03-02T02:46:01Z","timestamp":1709347561000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Microbiome diversity and zoonotic bacterial pathogen prevalence in\n                    <i>Peromyscus<\/i>\n                    mice from agricultural landscapes and synanthropic habitat"],"prefix":"10.1111","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9591-622X","authenticated-orcid":false,"given":"Janine","family":"Mistrick","sequence":"first","affiliation":[{"name":"Department of Ecology, Evolution and Behavior, College of Biological Sciences University of Minnesota  St. Paul Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evan J.","family":"Kipp","sequence":"additional","affiliation":[{"name":"Department of Veterinary and Biomedical Sciences, College of Veterinary Medicine University of Minnesota  St. Paul Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah I.","family":"Weinberg","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Collin C.","family":"Adams","sequence":"additional","affiliation":[{"name":"Itasca Biological Station and Laboratories University of Minnesota  Lake Itasca Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter A.","family":"Larsen","sequence":"additional","affiliation":[{"name":"Department of Veterinary and Biomedical Sciences, College of Veterinary Medicine University of Minnesota  St. Paul Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meggan E.","family":"Craft","sequence":"additional","affiliation":[{"name":"Department of Ecology, Evolution and Behavior, College of Biological Sciences University of Minnesota  St. Paul Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,3]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/ismej.2013.16"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ece3.9216"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00248\u2010020\u201001569\u20108"},{"key":"e_1_2_12_5_1","volume-title":"Foodborne illnesses and germs","author":"CDC","year":"2022"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41592\u2010022\u201001520\u20104"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bty149"},{"key":"e_1_2_12_8_1","unstructured":"Dewitz J.(2021).National Land Cover Database (NLCD) 2019 products[Dataset]. U.S. Geological Survey.https:\/\/doi.org\/10.5066\/P9KZCM54"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.01102"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1098\/rsbl.2022.0547"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.76381"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010022\u201035273\u20107"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/s42003\u2010021\u201002315\u20107"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.01933\u201014"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/1462\u20102920.15601"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0209200"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010020\u201080782\u20104"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010020\u20102562\u20108"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10393\u2010014\u20100941\u2010z"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00436\u2010009\u20101400\u20106"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2016.04.007"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1501598112"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tree.2016.09.012"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1186\/s42523\u2010023\u201000237\u20109"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0164402"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/ece3.5228"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens10091183"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12866\u2010020\u201001979\u20101"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.epidem.2009.03.002"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41592\u2010023\u201002092\u20107"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/mec.15240"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1186\/s42523\u2010023\u201000229\u20109"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl\u20102015\u2010309990"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0061217"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10344\u2010019\u20101344\u20109"},{"key":"e_1_2_12_36_1","unstructured":"Mistrick J. Kipp E. J. Craft M. E. &Larsen P. A.(2024).Peromyscus mouse gut microbiome in agricultural and synanthropic habitat in Minnesota USA. National Center for Biotechnology Information Sequence Read Archive.https:\/\/www.ncbi.nlm.nih.gov\/bioproject\/1068550[Dataset]."},{"key":"e_1_2_12_37_1","doi-asserted-by":"crossref","unstructured":"Mistrick J. Weinberg S. I. Adams C. C. &Craft M. E.(2024).Microbiome diversity and zoonotic bacterial pathogen prevalence in Peromyscus mice from agricultural landscapes and synanthropic habitat. Dryad.https:\/\/doi.org\/10.5061\/dryad.7m0cfxq2m[Dataset].","DOI":"10.1111\/mec.17309"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.1093\/jas\/skaa248"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0220926"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/fee.2126"},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.3389\/fevo.2022.742369"},{"key":"e_1_2_12_42_1","unstructured":"Oksanen J. Blanchet F. G. Friendly M. Kindt R. Legendre P. McGlinn D. Minchin P. R. O'Hara R. B. Simpson G. L. Solymos P. &Stevens M. H. H.(2022).Vegan: Community ecology package. R package version 2.5\u20102.7. 2020."},{"key":"e_1_2_12_43_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkv1189"},{"key":"e_1_2_12_44_1","doi-asserted-by":"publisher","DOI":"10.3389\/fevo.2018.00148"},{"key":"e_1_2_12_45_1","volume-title":"R: A language and environment for statistical computing","author":"R Core Team","year":"2023"},{"key":"e_1_2_12_46_1","doi-asserted-by":"publisher","DOI":"10.7589\/2019\u201004\u2010099"},{"key":"e_1_2_12_47_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010020\u20102971\u20108"},{"key":"e_1_2_12_48_1","doi-asserted-by":"publisher","DOI":"10.21105\/joss.02991"},{"key":"e_1_2_12_49_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1009514"},{"key":"e_1_2_12_50_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gku1201"},{"key":"e_1_2_12_51_1","doi-asserted-by":"publisher","DOI":"10.1111\/vcp.13031"},{"key":"e_1_2_12_52_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010020\u201078891\u20101"},{"key":"e_1_2_12_53_1","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms11030804"},{"key":"e_1_2_12_54_1","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.2019.2182"},{"key":"e_1_2_12_55_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkz904"},{"key":"e_1_2_12_56_1","doi-asserted-by":"publisher","DOI":"10.1177\/1040638719899081"},{"key":"e_1_2_12_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2020.144166"},{"key":"e_1_2_12_58_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmicrobiol.2017.121"}],"container-title":["Molecular Ecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/mec.17309","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/mec.17309","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,25]],"date-time":"2024-03-25T08:01:10Z","timestamp":1711353670000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/mec.17309"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3]]},"references-count":57,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["10.1111\/mec.17309"],"URL":"https:\/\/doi.org\/10.1111\/mec.17309","archive":["Portico"],"relation":{},"ISSN":["0962-1083","1365-294X"],"issn-type":[{"value":"0962-1083","type":"print"},{"value":"1365-294X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3]]},"assertion":[{"value":"2023-07-31","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-02-01","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e17309"}}