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Recently, dynamic measurement of retinal vessel caliber using flicker light stimulation has been used to evaluate potential endothelial dysfunction and other mechanisms in CVD. A variety of studies now indicate that retinal vasodilation during flicker light simulation is reduced in diabetes, hypertension, hyperlipidemia and obesity, and may be influenced by age and race\/ethnicity. These data suggest that flicker light\u2010induced retinal vasodilation may be a unique and non\u2010invasive measure of endothelial dysfunction. This review focuses recent studies on systemic associations of flicker light\u2010induced retinal vasodilation, and discusses the potential for future research in this area.<\/jats:p>","DOI":"10.1111\/micc.12026","type":"journal-article","created":{"date-parts":[[2012,11,15]],"date-time":"2012-11-15T23:05:16Z","timestamp":1353020716000},"page":"257-268","source":"Crossref","is-referenced-by-count":69,"title":["Systemic Associations of Dynamic Retinal Vessel Analysis: A Review of Current Literature"],"prefix":"10.1111","volume":"20","author":[{"given":"Michelle","family":"Lim","sequence":"first","affiliation":[{"name":"Centre for Eye Research Australia University of Melbourne Melbourne Australia"},{"name":"Singapore Eye Research Institute Yong Loo Lin School of Medicine National University of Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad B.","family":"Sasongko","sequence":"additional","affiliation":[{"name":"Centre for Eye Research 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