{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T11:38:35Z","timestamp":1769168315798,"version":"3.49.0"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,1,6]],"date-time":"2015-01-06T00:00:00Z","timestamp":1420502400000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microcirculation"],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Microcirculatory visualization has already been used to investigate buccal and cutaneous microcirculatory alterations in neonates. Still, the reproducibility of these microvascular measurements has never been studied in (premature) neonates. This study aimed to determine the reproducibility of microvascular vessel density in cutaneous and buccal <jats:styled-content style=\"fixed-case\">SDF<\/jats:styled-content> clips in one\u2010day\u2010old term newborns.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Buccal and cutaneous microcirculations were measured using <jats:styled-content style=\"fixed-case\">SDF<\/jats:styled-content> imaging. Vessel density was independently assessed by two investigators. Reproducibility was assessed from the <jats:styled-content style=\"fixed-case\">ICC<\/jats:styled-content> and Bland\u2013Altman analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Reproducibility of vessel density assessment in the buccal area was good, with <jats:styled-content style=\"fixed-case\">ICC<\/jats:styled-content>s for total and PVD of 0.93 (0.88\u20130.97) and 0.93 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0.85\u20130.97), respectively, and a near zero bias and acceptable limits of agreement in the Bland\u2013Altman analysis. Reproducibility of assessment of the cutaneous microcirculation was poor with <jats:styled-content style=\"fixed-case\">ICC<\/jats:styled-content>s for total and PVD of 0.31 (0\u20130.70) and 0.37 (0\u20130.74), respectively, and large biases (3.09 and 2.53) in the Bland\u2013Altman analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Evaluation of buccal microvascular vessel density in <jats:styled-content style=\"fixed-case\">SDF<\/jats:styled-content>\u2010derived images in term newborns is reproducible in contrary to the cutaneous vessel density.<\/jats:p><\/jats:sec>","DOI":"10.1111\/micc.12163","type":"journal-article","created":{"date-parts":[[2014,8,20]],"date-time":"2014-08-20T11:41:18Z","timestamp":1408534878000},"page":"37-43","source":"Crossref","is-referenced-by-count":17,"title":["Reproducibility of Microvascular Vessel Density Analysis in Sidestream Dark\u2010Field\u2010Derived Images of Healthy Term Newborns"],"prefix":"10.1111","volume":"22","author":[{"given":"Victor J.","family":"van den Berg","sequence":"first","affiliation":[{"name":"Department of Pediatrics Division of Neonatology Erasmus MC\u2010Sophia University Medical Center Rotterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hugo A.","family":"van Elteren","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Division of Neonatology Erasmus MC\u2010Sophia University Medical Center Rotterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erik A. B.","family":"Buijs","sequence":"additional","affiliation":[{"name":"Intensive Care and Department of Pediatric Surgery Erasmus MC\u2010Sophia University Medical Center Rotterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Can","family":"Ince","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Erasmus MC University Medical Center Rotterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dick","family":"Tibboel","sequence":"additional","affiliation":[{"name":"Intensive Care and Department of Pediatric Surgery Erasmus MC\u2010Sophia University Medical Center Rotterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irwin K. M.","family":"Reiss","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Division of Neonatology Erasmus MC\u2010Sophia University Medical Center Rotterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rogier C. J.","family":"de Jonge","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Division of Neonatology Erasmus MC\u2010Sophia University Medical Center Rotterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,1,6]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.328.7441.702"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/cc11236"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2013.10.024"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.12475"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200109-016OC"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/cc6118"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1203\/01.PDR.0000141982.38959.10"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-200203000-00019"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1364\/OE.15.015101"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/13529"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2009.08.034"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1080\/10739680802461935"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1203\/PDR.0b013e318184134e"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(86)90837-8"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-012-2476-5"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1970.tb07993.x"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000138558.16257.3F"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1177\/000331977102200507"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.86.2.420"},{"key":"e_1_2_10_21_1","first-page":"372956","article-title":"The microcirculation is unchanged in neonates with severe respiratory failure after the initiation of ECMO treatment","volume":"2012","author":"Top AP","year":"2012","journal-title":"Crit Care Res Pract"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e3181fb7994"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0b013e31820ac0b3"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e3181962a5f"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2006.08.021"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1203\/PDR.0b013e3181b3b1f6"}],"container-title":["Microcirculation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fmicc.12163","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/micc.12163","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T14:53:53Z","timestamp":1696172033000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/micc.12163"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["10.1111\/micc.12163"],"URL":"https:\/\/doi.org\/10.1111\/micc.12163","archive":["Portico"],"relation":{},"ISSN":["1073-9688","1549-8719"],"issn-type":[{"value":"1073-9688","type":"print"},{"value":"1549-8719","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,1]]}}}