{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T05:33:52Z","timestamp":1781588032245,"version":"3.54.5"},"reference-count":32,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2017,10,7]],"date-time":"2017-10-07T00:00:00Z","timestamp":1507334400000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microcirculation"],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Superficial skin papillary capillaries with blood supply from a superficial vascular plexus and regulated by local metabolic needs supply oxygen and nutrients for epithelial cell proliferation. A deep vascular plexus regulated by autonomous nerves serves body thermoregulation. In healthy volunteers, we assessed circulatory effects of a standardized skin trauma by <jats:styled-content style=\"fixed-case\">CAVM<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> DRS<\/jats:styled-content>, and <jats:styled-content style=\"fixed-case\">LDPM<\/jats:styled-content> to assess the measuring depth of the three techniques and to describe the acute trauma effects on nutritive and thermoregulatory perfusion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Volunteers (n=12) were examined at baseline and after induction of a 5.0\u00a0mm\u00d71.0\u00a0mm incision on the forearm; 30\u00a0minutes after the trauma induction, data were collected at 0\u20101, 2\u20103 and 30\u00a0mm distances.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>LDPM showed hyperemia at 2\u20103\u00a0mm distance (35.8\u00b115.2\u00a0a.u.), but not at 30\u00a0mm distance (7.4\u00b12.5\u00a0a.u.) compared to baseline (8.8\u00b11.8\u00a0a.u.). The <jats:styled-content style=\"fixed-case\">DRS<\/jats:styled-content> saturation increased at 2\u20103\u00a0mm (71.2\u00b14.8%), but not at 30\u00a0mm (49.8\u00b17.9%) compared to baseline (45.8\u00b17.4%). Capillary density and flow velocities were unaffected at all distances.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The results indicate that skin nutritive papillary capillary function can be assessed by <jats:styled-content style=\"fixed-case\">CAVM<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">DRS<\/jats:styled-content>, but not with <jats:styled-content style=\"fixed-case\">LDPM<\/jats:styled-content> because of its dependence of the deep plexus perfusion.<\/jats:p><\/jats:sec>","DOI":"10.1111\/micc.12389","type":"journal-article","created":{"date-parts":[[2017,6,20]],"date-time":"2017-06-20T18:46:40Z","timestamp":1497984400000},"source":"Crossref","is-referenced-by-count":6,"title":["Acute skin trauma induces hyperemia, but superficial papillary nutritive perfusion remains unchanged"],"prefix":"10.1111","volume":"24","author":[{"given":"Liv Kristin","family":"Sundheim","sequence":"first","affiliation":[{"name":"Circulation 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