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While von Willebrand disease has long been known to result from qualitative and quantitative deficiencies of <jats:styled-content style=\"fixed-case\">VWF<\/jats:styled-content>, it is recently that contribution of elevated levels of <jats:styled-content style=\"fixed-case\">VWF<\/jats:styled-content> to various pathological conditions including thrombosis, inflammation, angiogenesis, and cancer metastasis has been appreciated. Here, we discuss contribution of elevated levels of <jats:styled-content style=\"fixed-case\">VWF<\/jats:styled-content> to various thrombotic and nonthrombotic pathological conditions.<\/jats:p>","DOI":"10.1111\/micc.12510","type":"journal-article","created":{"date-parts":[[2018,10,26]],"date-time":"2018-10-26T14:26:07Z","timestamp":1540563967000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Von Willebrand factor contribution to pathophysiology outside of von Willebrand disease"],"prefix":"10.1111","volume":"26","author":[{"given":"Anahita","family":"Mojiri","sequence":"first","affiliation":[{"name":"Department of Medicine University of Alberta  Edmonton Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Parnian","family":"Alavi","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Alberta  Edmonton Alberta 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