{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:39:00Z","timestamp":1753879140003,"version":"3.41.2"},"reference-count":34,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,1,30]],"date-time":"2019-01-30T00:00:00Z","timestamp":1548806400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Microcirculation"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the efficacy, safety and long\u2010term outcome of <jats:styled-content style=\"fixed-case\">TIPP<\/jats:styled-content> for the adjunct therapy of superficial venous reflux\u2010related VLUs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 93 consecutive patients (104 legs) with superficial venous insufficiency\u2010related <jats:styled-content style=\"fixed-case\">VLU<\/jats:styled-content>s who underwent <jats:styled-content style=\"fixed-case\">TIPP<\/jats:styled-content> (53 legs) or conventional phlebectomy (51 legs) between January 2010 and December 2013 were retrospectively studied.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Compared to patients in the conventional phlebectomy group, <jats:styled-content style=\"fixed-case\">TIPP<\/jats:styled-content> patients had larger ulcer areas before surgery (<jats:italic>P\u00a0<\/jats:italic>&lt;\u00a00.005). However, <jats:styled-content style=\"fixed-case\">TIPP<\/jats:styled-content> group required a significantly shorter operation time (<jats:italic>P\u00a0<\/jats:italic>&lt;\u00a00.005), fewer incisions (<jats:italic>P\u00a0<\/jats:italic>&lt;\u00a00.005) but less ulcer healing time (1.25\u00a0month vs 2.5\u00a0months, <jats:italic>P\u00a0<\/jats:italic>&lt;\u00a00.05). No significant difference in in\u2010hospital and follow\u2010up complications was found between the two groups. For long\u2010term outcome, <jats:styled-content style=\"fixed-case\">TIPP<\/jats:styled-content> group leaded a lower ulcer recurrence rate at 36\u00a0months (13.2% vs 29.4%, <jats:italic>P\u00a0<\/jats:italic>&lt;\u00a00.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">TIPP<\/jats:styled-content> may be an adjunct surgical method contributes to healing of <jats:styled-content style=\"fixed-case\">VLU<\/jats:styled-content>s, especially for large ulcer areas.<\/jats:p><\/jats:sec>","DOI":"10.1111\/micc.12523","type":"journal-article","created":{"date-parts":[[2018,12,17]],"date-time":"2018-12-17T05:50:37Z","timestamp":1545025837000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Transilluminated powered phlebectomy in the treatment of large area venous leg ulcers: A case\u2010control study with 3\u00a0years 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