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The parasite must change its transcriptional profile in order to establish and maintain infection. However, few core regulatory elements and transcription factors have been identified to date and little is known about other mechanisms that may control these rapid changes in gene expression during parasite infection. In the last years, epigenetic mechanisms involved in the regulation of gene expression have been gaining major attention in this parasite. In this review, we summarize and discuss the major advances of the last few years with regard to epigenetics (DNA methylation, post\u2010translational histone modifications, and histone variants) in the parasite\n                    <jats:italic>T. vaginalis<\/jats:italic>\n                    . These studies can shed light into our current understanding of this parasite's biology with far\u2010reaching implications for the prognosis and treatment of trichomoniasis.\n                  <\/jats:p>","DOI":"10.1111\/mmi.14704","type":"journal-article","created":{"date-parts":[[2021,2,18]],"date-time":"2021-02-18T04:23:25Z","timestamp":1613622205000},"page":"959-967","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Toward incorporating epigenetics into regulation of gene expression in the parasite\n                    <i>Trichomonas<\/i>\n                    <i>vaginalis<\/i>"],"prefix":"10.1111","volume":"115","author":[{"given":"Ayelen","family":"Lizarraga","sequence":"first","affiliation":[{"name":"Laboratorio de Par\u00e1sitos Anaerobios Instituto Tecnol\u00f3gico Chascom\u00fas (INTECH) CONICET\u2010UNSAM Chascom\u00fas 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