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They act as adaptors at various subcellular locales to mediate several protein\u2010protein interactions in a spatio\u2010temporal manner. Here, we characterize shugoshin (Sgo1) in the human fungal pathogen\n                    <jats:italic>Candida albicans<\/jats:italic>\n                    . We observe that Sgo1 retains its centromeric localization and performs its conserved functions of regulating the sister chromatid biorientation, centromeric condensin localization, and maintenance of chromosomal passenger complex (CPC). We identify novel roles of Sgo1 as a spindle assembly checkpoint (SAC) component with functions in maintaining a prolonged SAC response by retaining Mad2 and Bub1 at the kinetochores in response to improper kinetochore\u2010microtubule attachments. Strikingly, we discover the in vivo localization of Sgo1 along the length of the mitotic spindle. Our results indicate that Sgo1 performs a hitherto unknown function of facilitating timely disassembly of the mitotic spindle in\n                    <jats:italic>C. albicans<\/jats:italic>\n                    . To summarize, this study unravels a unique functional adaptation of shugoshin in maintaining genomic stability.\n                  <\/jats:p>","DOI":"10.1111\/mmi.14796","type":"journal-article","created":{"date-parts":[[2021,8,18]],"date-time":"2021-08-18T13:45:20Z","timestamp":1629294320000},"page":"1079-1098","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Shugoshin ensures maintenance of the spindle assembly checkpoint response and efficient spindle disassembly"],"prefix":"10.1111","volume":"116","author":[{"given":"Aakanksha","family":"Sane","sequence":"first","affiliation":[{"name":"Department of Biosciences and Bioengineering Indian Institute of Technology Bombay, Powai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shreyas","family":"Sridhar","sequence":"additional","affiliation":[{"name":"Molecular Biology &amp; Genetics Unit Jawaharlal Nehru Centre for Advanced Scientific Research 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