{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T04:23:46Z","timestamp":1768278226053,"version":"3.49.0"},"reference-count":72,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2017,1,3]],"date-time":"2017-01-03T00:00:00Z","timestamp":1483401600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100007565","name":"Citrus Research and Development Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007565","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bsppjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Molecular Plant Pathology"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Xanthomonas citri<\/jats:italic>\n                    ssp.\n                    <jats:italic>citri<\/jats:italic>\n                    (\n                    <jats:italic>X. citri<\/jats:italic>\n                    ) is the causal agent of Asiatic citrus canker, a disease that seriously affects most commercially important\n                    <jats:italic>Citrus<\/jats:italic>\n                    species worldwide. We have identified previously a natural variant,\n                    <jats:italic>X. citri<\/jats:italic>\n                    A\n                    <jats:sup>T<\/jats:sup>\n                    , that triggers a host\u2010specific defence response in\n                    <jats:italic>Citrus limon<\/jats:italic>\n                    . However, the mechanisms involved in this canker disease resistance are unknown. In this work, the defence response induced by\n                    <jats:italic>X. citri<\/jats:italic>\n                    A\n                    <jats:sup>T<\/jats:sup>\n                    was assessed by transcriptomic, physiological and ultrastructural analyses, and the effects on bacterial biofilm formation were monitored in parallel. We show that\n                    <jats:italic>X. citri<\/jats:italic>\n                    A\n                    <jats:sup>T<\/jats:sup>\n                    triggers a hypersensitive response associated with the interference of biofilm development and arrest of bacterial growth in\n                    <jats:italic>C. limon<\/jats:italic>\n                    . This plant response involves an extensive transcriptional reprogramming, setting in motion cell wall reinforcement, the oxidative burst and the accumulation of salicylic acid (SA) and phenolic compounds. Ultrastructural analyses revealed subcellular changes involving the activation of autophagy\u2010associated vacuolar processes. Our findings show the activation of SA\u2010dependent defence in response to\n                    <jats:italic>X. citri<\/jats:italic>\n                    A\n                    <jats:sup>T<\/jats:sup>\n                    and suggest a coordinated regulation between the SA and flavonoid pathways, which is associated with autophagy mechanisms that control pathogen invasion in\n                    <jats:italic>C. limon<\/jats:italic>\n                    . Furthermore, this defence response protects\n                    <jats:italic>C. limon<\/jats:italic>\n                    plants from disease on subsequent challenges by pathogenic\n                    <jats:italic>X. citri<\/jats:italic>\n                    . This knowledge will allow the rational exploitation of the plant immune system as a biotechnological approach for the management of the disease.\n                  <\/jats:p>","DOI":"10.1111\/mpp.12489","type":"journal-article","created":{"date-parts":[[2016,9,20]],"date-time":"2016-09-20T05:32:44Z","timestamp":1474349564000},"page":"1267-1281","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Resistance to citrus canker induced by a variant of\n                    <i>Xanthomonas citri<\/i>\n                    ssp.\n                    <i>citri<\/i>\n                    is associated with a hypersensitive cell death response involving autophagy\u2010associated vacuolar processes"],"prefix":"10.1111","volume":"18","author":[{"given":"Roxana A.","family":"Roeschlin","sequence":"first","affiliation":[{"name":"Instituto de Biolog\u00eda Molecular y Celular de Rosario (IBR)\u2013Consejo Nacional de Investigaciones Cient\u00edficas y Tecnol\u00f3gicas (CONICET) \u00c1rea Virolog\u00eda, Facultad de Ciencias Bioqu\u00edmicas y Farmac\u00e9uticas, Universidad Nacional de Rosario (UNR), Ocampo y Esmeralda s\/n Rosario S2000FHN Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda A.","family":"Favaro","sequence":"additional","affiliation":[{"name":"Instituto de Biolog\u00eda Molecular y Celular de Rosario (IBR)\u2013Consejo Nacional de Investigaciones Cient\u00edficas y Tecnol\u00f3gicas (CONICET) \u00c1rea Virolog\u00eda, Facultad de Ciencias Bioqu\u00edmicas y Farmac\u00e9uticas, Universidad Nacional de Rosario (UNR), Ocampo y Esmeralda s\/n Rosario S2000FHN Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda A.","family":"Chiesa","sequence":"additional","affiliation":[{"name":"Instituto de Biolog\u00eda Molecular y Celular de Rosario (IBR)\u2013Consejo Nacional de Investigaciones Cient\u00edficas y Tecnol\u00f3gicas (CONICET) \u00c1rea Virolog\u00eda, Facultad de Ciencias Bioqu\u00edmicas y Farmac\u00e9uticas, Universidad Nacional de Rosario (UNR), Ocampo y Esmeralda s\/n Rosario S2000FHN Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergio","family":"Alemano","sequence":"additional","affiliation":[{"name":"Laboratorio de Fisiolog\u00eda Vegetal, Departamento de Ciencias Naturales, Facultad de Ciencias Exactas, F\u00edsico\u2010Qu\u00edmicas y Naturales Universidad Nacional de R\u00edo Cuarto, Ruta 36 Km. 601 R\u00edo Cuarto X5804ZAB C\u00f3rdoba Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adri\u00e1n A.","family":"Vojnov","sequence":"additional","affiliation":[{"name":"Instituto de Ciencia y Tecnolog\u00eda Dr. Cesar Milstein Fundaci\u00f3n Pablo Cassar\u00e1\u2010CONICET, Saladillo 2468 Ciudad de Buenos Aires C1440FFX Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atilio P.","family":"Castagnaro","sequence":"additional","affiliation":[{"name":"Instituto de Tecnolog\u00eda Agroindustrial del Noroeste Argentino (ITA\u2010NOA) Estaci\u00f3n Experimental Agroindustrial Obispo Colombres (EEAOC)\u2010CONICET, Av. William Cross 3150 Las Talitas Tucum\u00e1n T4101XAC Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda P.","family":"Filippone","sequence":"additional","affiliation":[{"name":"Instituto de Tecnolog\u00eda Agroindustrial del Noroeste Argentino (ITA\u2010NOA) Estaci\u00f3n Experimental Agroindustrial Obispo Colombres (EEAOC)\u2010CONICET, Av. William Cross 3150 Las Talitas Tucum\u00e1n T4101XAC Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"jr","given":"Frederick G.","family":"Gmitter","sequence":"additional","affiliation":[{"name":"Citrus Research and Education Center (CREC) University of Florida, 700 Experiment Station Rd. 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