{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T00:45:07Z","timestamp":1789865107734,"version":"4.0.1"},"reference-count":72,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,12,26]],"date-time":"2017-12-26T00:00:00Z","timestamp":1514246400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Plant Health Care Inc.","award":["#1000"],"award-info":[{"award-number":["#1000"]}]}],"content-domain":{"domain":["bsppjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Molecular Plant Pathology"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    Ferredoxins, the major distributors for electrons to various acceptor systems in plastids, contribute to redox regulation and antioxidant defence in plants. However, their function in plant immunity is not fully understood. In this study, we show that the expression of the major leaf ferredoxin gene\n                    <jats:italic>Fd2<\/jats:italic>\n                    is suppressed by\n                    <jats:italic>Pseudomonas syringae<\/jats:italic>\n                    pv.\n                    <jats:italic>tomato<\/jats:italic>\n                    (\n                    <jats:italic>Pst<\/jats:italic>\n                    ) DC3000 infection, and that knockout of\n                    <jats:italic>Fd2<\/jats:italic>\n                    (\n                    <jats:italic>Fd2\u2010KO<\/jats:italic>\n                    ) in Arabidopsis increases the plant's susceptibility to both\n                    <jats:italic>Pst<\/jats:italic>\n                    DC3000 and\n                    <jats:italic>Golovinomyces cichoracearum<\/jats:italic>\n                    . On\n                    <jats:italic>Pst<\/jats:italic>\n                    DC3000 infection, the\n                    <jats:italic>Fd2\u2010KO<\/jats:italic>\n                    mutant accumulates increased levels of jasmonic acid and displays compromised salicylic acid\u2010related immune responses.\n                    <jats:italic>Fd2\u2010KO<\/jats:italic>\n                    also shows defects in the accumulation of reactive oxygen species induced by pathogen\u2010associated molecular pattern\u2010triggered immunity. However,\n                    <jats:italic>Fd2\u2010KO<\/jats:italic>\n                    shows enhanced R\u2010protein\u2010mediated resistance to\n                    <jats:italic>Pst<\/jats:italic>\n                    DC3000\/\n                    <jats:italic>AvrRpt2<\/jats:italic>\n                    infection, suggesting that Fd2 plays a negative role in effector\u2010triggered immunity. Furthermore, Fd2 interacts with FIBRILLIN4 (FIB4), a harpin\u2010binding protein localized in chloroplasts. Interestingly, Fd2, but not FIB4, localizes to stromules that extend from chloroplasts. Taken together, our results demonstrate that Fd2 plays an important role in plant immunity.\n                  <\/jats:p>","DOI":"10.1111\/mpp.12621","type":"journal-article","created":{"date-parts":[[2017,10,4]],"date-time":"2017-10-04T06:20:47Z","timestamp":1507098047000},"page":"1377-1390","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["The major leaf ferredoxin Fd2 regulates plant innate immunity in Arabidopsis"],"prefix":"10.1111","volume":"19","author":[{"given":"Mo","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Plant Pathology Ohio State University Columbus OH 43210 USA"},{"name":"Key Laboratory of Ministry of Education for Genetics, Breeding and Multiple Utilization of Crops Plant Immunity Center, Fujian Agriculture and Forestry University  Fuzhou 350002 China"},{"name":"Fujian University Key Laboratory for Plant\u2013Microbe Interaction Fujian Agriculture and Forestry University  Fuzhou 350002 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Rui","sequence":"additional","affiliation":[{"name":"Key Laboratory of Ministry of Education for Genetics, Breeding and Multiple Utilization of Crops Plant Immunity Center, Fujian Agriculture and Forestry University  Fuzhou 350002 China"},{"name":"State Key Laboratory of Ecological Control of Fujian\u2010Taiwan Crop Pests Fujian Agriculture and Forestry University  Fuzhou 350002 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haojie","family":"Yan","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Plant Cell and Chromosome Engineering Institute of Genetics and Developmental Biology, Chinese Academy of Sciences Beijing 100101 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Shi","sequence":"additional","affiliation":[{"name":"Key Laboratory of Ministry of Education for Genetics, Breeding and Multiple Utilization of Crops Plant Immunity Center, Fujian Agriculture and Forestry University  Fuzhou 350002 China"},{"name":"State Key Laboratory of Ecological Control of Fujian\u2010Taiwan Crop Pests Fujian Agriculture and Forestry University  Fuzhou 350002 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanying","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Horticulture and Crop Science Ohio State University, Columbus\/Wooster  OH 43210 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinshan Ella","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Horticulture and Crop Science Ohio State University, Columbus\/Wooster  OH 43210 USA"},{"name":"Department of Horticulture and Crop Sciences OARDC Metabolite Analysis Cluster (OMAC) Wooster OH 44691 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Plant Pathology Ohio State University Columbus OH 43210 USA"},{"name":"State Key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant Protection, Chinese Academy of Agricultural Sciences  Beijing 100193 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua J.","family":"Blakeslee","sequence":"additional","affiliation":[{"name":"Department of Horticulture and Crop Science Ohio State University, Columbus\/Wooster  OH 43210 USA"},{"name":"Department of Horticulture and Crop Sciences OARDC Metabolite Analysis Cluster (OMAC) Wooster OH 44691 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Mackey","sequence":"additional","affiliation":[{"name":"Department of Horticulture and Crop Science Ohio State University, Columbus\/Wooster  OH 43210 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dingzhong","family":"Tang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Ministry of Education for Genetics, Breeding and Multiple Utilization of Crops Plant Immunity Center, Fujian Agriculture and Forestry University  Fuzhou 350002 China"},{"name":"State Key Laboratory of Ecological Control of Fujian\u2010Taiwan Crop Pests Fujian Agriculture and Forestry University  Fuzhou 350002 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongmin","family":"Wei","sequence":"additional","affiliation":[{"name":"Plant Health Care, Inc. 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