{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T07:25:25Z","timestamp":1784618725571,"version":"3.55.0"},"reference-count":64,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2022,3,13]],"date-time":"2022-03-13T00:00:00Z","timestamp":1647129600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31871925"],"award-info":[{"award-number":["31871925"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013314","name":"Higher Education Discipline Innovation Project","doi-asserted-by":"publisher","award":["B18044"],"award-info":[{"award-number":["B18044"]}],"id":[{"id":"10.13039\/501100013314","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bsppjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Molecular Plant Pathology"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Huanglongbing (HLB), associated with \u201c\n                    <jats:italic>Candidatus<\/jats:italic>\n                    Liberibacter asiaticus\u201d (CLas), is a globally devastating plant disease. The highly reduced genome of CLas encodes a number of secretory proteins. The conserved prophage\u2010encoded protein AGH17470 is herein identified as a nonclassical secretory protein. We confirmed that the N\u2010terminal and C\u2010terminal sequences jointly determine the secretion of AGH17470. The transient expression of AGH17470 protein in\n                    <jats:italic>Nicotiana benthamiana<\/jats:italic>\n                    caused hypersensitive response (HR) cell death in infiltrated leaves and systemically infected leaves as well as the dwarfing of the entire plant, suggesting that AGH17470 is involved in the plant immune response, growth, and development. Overexpression of\n                    <jats:italic>AGH17470<\/jats:italic>\n                    in\n                    <jats:italic>N.\u00a0benthamiana<\/jats:italic>\n                    and citrus plants up\u2010regulated the transcription of pathogenesis\u2010related and salicylic acid (SA)\u2010signalling pathway genes and promoted SA accumulation. Furthermore, transient expression of\n                    <jats:italic>AGH17470<\/jats:italic>\n                    enhanced the resistance of sweet orange to\n                    <jats:italic>Xanthomonas citri<\/jats:italic>\n                    subsp.\n                    <jats:italic>citri<\/jats:italic>\n                    . To our knowledge, AGH17470 is the first prophage\u2010encoded secretory protein demonstrated to elicit an HR and induce a strong plant immune response. The findings have increased our understanding of prophage\u2010encoded secretory protein genes, and the results provide clues as to the plant defence response against CLas.\n                  <\/jats:p>","DOI":"10.1111\/mpp.13206","type":"journal-article","created":{"date-parts":[[2022,3,13]],"date-time":"2022-03-13T13:03:55Z","timestamp":1647176635000},"page":"1022-1034","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["A prophage\u2010encoded nonclassical secretory protein of \u201c\n                    <i>Candidatus<\/i>\n                    Liberibacter asiaticus\u201d induces a strong immune response in\n                    <i>Nicotiana benthamiana<\/i>\n                    and citrus"],"prefix":"10.1111","volume":"23","author":[{"given":"Jiao","family":"Du","sequence":"first","affiliation":[{"name":"National Citrus Engineering Research Center Citrus Research Institute Southwest University  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiying","family":"Wang","sequence":"additional","affiliation":[{"name":"National Citrus Engineering Research Center Citrus Research Institute Southwest University  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunhua","family":"Zeng","sequence":"additional","affiliation":[{"name":"National Citrus Engineering Research Center Citrus Research Institute Southwest University  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changyong","family":"Zhou","sequence":"additional","affiliation":[{"name":"National Citrus Engineering Research Center Citrus Research Institute Southwest University  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9293-3427","authenticated-orcid":false,"given":"Xuefeng","family":"Wang","sequence":"additional","affiliation":[{"name":"National Citrus Engineering Research 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