{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:16:36Z","timestamp":1787015796734,"version":"build-2736575974"},"reference-count":56,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,11,15]],"date-time":"2022-11-15T00:00:00Z","timestamp":1668470400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32070167"],"award-info":[{"award-number":["32070167"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31772131"],"award-info":[{"award-number":["31772131"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["2020\u2010GH02\u201000026\u2010HZ"],"award-info":[{"award-number":["2020\u2010GH02\u201000026\u2010HZ"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bsppjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Molecular Plant Pathology"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Many host factors of plants are used by viruses to facilitate viral infection. However, little is known about how alpha\u2010momorcharin (\u03b1MMC) counters virus\u2010mediated attack strategies in tomato. Our present research revealed that the 2b protein of cucumber mosaic virus (CMV) directly interacted with catalases (CATs) and inhibited their activities. Further analysis revealed that transcription levels of catalase were induced by CMV infection and that virus accumulation increased in CAT\u2010silenced or 2b\u2010overexpressing tomato plants compared with that in control plants, suggesting that the interaction between 2b and catalase facilitated the accumulation of CMV in hosts. However, both CMV accumulation and viral symptoms were reduced in \u03b1MMC transgenic tomato plants, indicating that \u03b1MMC engaged in an antiviral role in the plant response to CMV infection. Molecular experimental analysis demonstrated that \u03b1MMC interfered with the interactions between catalases and 2b in a competitive manner, with the expression of \u03b1MMC inhibited by CMV infection. We further demonstrated that the inhibition of catalase activity by 2b was weakened by \u03b1MMC. Accordingly, \u03b1MMC transgenic plants exhibited a greater ability to maintain redox homeostasis than wild\u2010type plants when infected with CMV. Altogether, these results reveal that \u03b1MMC retains catalase activity to inhibit CMV infection by subverting the interaction between 2b and catalase in tomato.<\/jats:p>","DOI":"10.1111\/mpp.13279","type":"journal-article","created":{"date-parts":[[2022,11,15]],"date-time":"2022-11-15T04:46:01Z","timestamp":1668487561000},"page":"107-122","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Alpha\u2010momorcharin preserves catalase activity to inhibit viral infection by disrupting the 2b\u2013CAT interaction in\n                    <i>Solanum lycopersicum<\/i>"],"prefix":"10.1111","volume":"24","author":[{"given":"Ting","family":"Yang","sequence":"first","affiliation":[{"name":"Key Laboratory of Bio\u2010Resource and Eco\u2010Environment of Ministry of Education, College of Life Sciences Sichuan University  Chengdu China"},{"name":"Hubei Engineering Research Center for Protection and Utilization of Special Biological Resources in the Hanjiang River Basin, College of Life Sciences Jianghan University  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiding","family":"Peng","sequence":"additional","affiliation":[{"name":"Key Laboratory of Bio\u2010Resource and Eco\u2010Environment of Ministry of Education, College of Life Sciences Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Honghui","family":"Lin","sequence":"additional","affiliation":[{"name":"Key Laboratory of Bio\u2010Resource and Eco\u2010Environment of Ministry of Education, College of Life Sciences Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1314-1262","authenticated-orcid":false,"given":"Dehui","family":"Xi","sequence":"additional","affiliation":[{"name":"Key Laboratory of Bio\u2010Resource and Eco\u2010Environment of Ministry of Education, College of Life Sciences 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