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Transferring the resistance trait of\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Gossypium barbadense<\/jats:italic>\n                    <\/jats:styled-content>\n                    to\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>G. hirsutum<\/jats:italic>\n                    <\/jats:styled-content>\n                    is optional but challenging in traditional breeding due to limited molecular dissections of resistance genes. Here, we discovered a species\u2010diversified structural variation (SV) in the promoter of receptor\u2010like protein 6 (RLP6) that caused distinctly higher expression level of\n                    <jats:italic>RLP6<\/jats:italic>\n                    in\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>G. barbadense<\/jats:italic>\n                    <\/jats:styled-content>\n                    with the SV than\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>G. hirsutum<\/jats:italic>\n                    <\/jats:styled-content>\n                    without the SV. Functional experiments showed that\n                    <jats:italic>RLP6<\/jats:italic>\n                    is an important regulator in mediating VW resistance. Overexpressing\n                    <jats:italic>RLP6<\/jats:italic>\n                    significantly enhanced resistance and root growth, whereas the opposite phenotype appeared in\n                    <jats:italic>RLP6<\/jats:italic>\n                    \u2010silenced cotton. A series of experiments indicated that RLP6 regulated reactive oxygen species (ROS) and salicylic acid (SA) signalling, which induced diversified defence\u2010related gene expression with pathogenesis\u2010related (PR) proteins and cell wall proteins enrichments for resistance improvement. These findings could be valuable for the transfer of the\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>G. barbadense<\/jats:italic>\n                    <\/jats:styled-content>\n                    SV locus to improve\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>G. hirsutum<\/jats:italic>\n                    <\/jats:styled-content>\n                    VW resistance in future crop disease resistance breeding.\n                  <\/jats:p>","DOI":"10.1111\/mpp.70052","type":"journal-article","created":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T12:40:37Z","timestamp":1737549637000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Cotton\n                    <scp>RLP6<\/scp>\n                    Interacts With\n                    <scp>NDR1<\/scp>\n                    \/\n                    <scp>HIN6<\/scp>\n                    to Enhance Verticillium Wilt Resistance via Altering\n                    <scp>ROS<\/scp>\n                    and\n                    <scp>SA<\/scp>"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4560-9058","authenticated-orcid":false,"given":"Dongmei","family":"Zhang","sequence":"first","affiliation":[{"name":"State Key Laboratory of North China Crop Improvement and Regulation, North China Key Laboratory for Crop Germplasm Resources of Education Ministry, Hebei Provincial Key Laboratory of Crop Germplasm Resources Hebei Agricultural University  Baoding China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of North China Crop Improvement and Regulation, North China Key Laboratory for Crop Germplasm Resources of Education Ministry, Hebei Provincial Key Laboratory of Crop Germplasm Resources Hebei Agricultural University  Baoding China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qishen","family":"Gu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of North China Crop Improvement and Regulation, North China Key Laboratory for Crop Germplasm Resources of Education Ministry, Hebei Provincial Key Laboratory of Crop Germplasm Resources Hebei Agricultural University  Baoding China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lixia","family":"Liu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of North China Crop Improvement and Regulation, North China Key Laboratory for Crop Germplasm Resources of Education Ministry, Hebei Provincial Key Laboratory of Crop Germplasm Resources Hebei Agricultural University  Baoding China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhicheng","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of North China Crop Improvement and Regulation, North China Key Laboratory for Crop Germplasm Resources of Education Ministry, Hebei Provincial Key Laboratory of Crop Germplasm Resources Hebei Agricultural University  Baoding China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of North China Crop Improvement and Regulation, North China Key Laboratory for Crop Germplasm Resources of Education Ministry, Hebei Provincial Key Laboratory of Crop Germplasm Resources Hebei Agricultural University  Baoding China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengsheng","family":"Meng","sequence":"additional","affiliation":[{"name":"State Key Laboratory of North China Crop Improvement and Regulation, North China Key Laboratory for Crop Germplasm Resources of Education Ministry, Hebei Provincial Key Laboratory of Crop Germplasm Resources Hebei Agricultural University  Baoding China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1537-8159","authenticated-orcid":false,"given":"Jun","family":"Yang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of North China Crop Improvement and Regulation, North China Key Laboratory for Crop Germplasm Resources of Education Ministry, Hebei Provincial Key Laboratory of Crop Germplasm Resources Hebei Agricultural University  Baoding China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zixu","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of North China Crop Improvement and Regulation, North China Key Laboratory for Crop Germplasm Resources of Education Ministry, Hebei Provincial Key Laboratory of Crop Germplasm Resources Hebei Agricultural University  Baoding China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiying","family":"Ma","sequence":"additional","affiliation":[{"name":"State Key Laboratory of North China Crop Improvement and Regulation, North China Key Laboratory for Crop Germplasm Resources of Education Ministry, Hebei Provincial Key Laboratory of Crop Germplasm Resources Hebei Agricultural University  Baoding China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingfen","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of North China Crop Improvement and Regulation, North China Key Laboratory for Crop Germplasm Resources of Education Ministry, Hebei Provincial Key Laboratory of Crop Germplasm Resources Hebei Agricultural University  Baoding China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1596-8060","authenticated-orcid":false,"given":"Yan","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of North China Crop Improvement and Regulation, North China Key Laboratory for Crop Germplasm Resources of Education Ministry, Hebei Provincial Key Laboratory of Crop Germplasm Resources Hebei Agricultural University  Baoding 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