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Treatment with either\n                    <jats:italic>t<\/jats:italic>\n                    Z or BAPA significantly reduced bacterial growth after a later infection. This chemically induced resistance (IR) required the CK receptor AHK3, highlighting its critical role in mediating resistance by\n                    <jats:italic>t<\/jats:italic>\n                    Z and BAPA. This is remarkable as these compounds show either high or no affinity for this CK receptor, respectively. Surprisingly,\n                    <jats:italic>t<\/jats:italic>\n                    Z, but not BAPA, induced the expression of CK response genes, including\n                    <jats:italic>ARR5<\/jats:italic>\n                    , suggesting divergent mechanisms of action. Resistance caused by both compounds was abolished in the\n                    <jats:italic>npr1<\/jats:italic>\n                    mutant, underpinning the functional relevance of the salicylic acid (SA) signalling pathway. Transcriptomic analysis showed that both BAPA and\n                    <jats:italic>t<\/jats:italic>\n                    Z triggered the expression of distinct sets of genes associated with SA and reactive oxygen species (ROS) but not with jasmonic acid (JA) signalling. BAPA and, to a lesser extent, also\n                    <jats:italic>t<\/jats:italic>\n                    Z activated pattern\u2010triggered immunity (PTI) signalling genes, including genes responsible for PTI signal amplification (\n                    <jats:italic>PREPIP2<\/jats:italic>\n                    ) and pathogen\u2010associated molecular pattern (PAMP) signalling (\n                    <jats:italic>PH1<\/jats:italic>\n                    ,\n                    <jats:italic>IDL6<\/jats:italic>\n                    ). This supported the hypothesis that the PTI pathway mediates the protective effect. Similarities and differences of chemically triggered IR by\n                    <jats:italic>t<\/jats:italic>\n                    Z and BAPA, as well as their potential for application, are discussed.\n                  <\/jats:p>","DOI":"10.1111\/mpp.70200","type":"journal-article","created":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T05:22:12Z","timestamp":1768022532000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Chemically Induced Resistance to Pathogen Infection in\n                    <i>Arabidopsis<\/i>\n                    by Cytokinin (\n                    <i>Trans<\/i>\n                    \u2010Zeatin) and an Aromatic Cytokinin Arabinoside"],"prefix":"10.1111","volume":"27","author":[{"given":"Martin","family":"H\u00f6nig","sequence":"first","affiliation":[{"name":"Institute of Biology\/Applied Genetics, Dahlem Centre of Plant Sciences Freie Universit\u00e4t Berlin  Berlin Germany"},{"name":"Department of Chemical Biology, Faculty of Science Palack\u00fd University  Olomouc Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Cortleven","sequence":"additional","affiliation":[{"name":"Institute of Biology\/Applied Genetics, Dahlem Centre of Plant Sciences Freie Universit\u00e4t Berlin  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan","family":"Pet\u0159\u00edk","sequence":"additional","affiliation":[{"name":"Laboratory of Growth Regulators, Faculty of Science, Palack\u00fd University &amp; Institute of Experimental Botany The Czech Academy of Sciences  Olomouc Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Radim","family":"Simersk\u00fd","sequence":"additional","affiliation":[{"name":"Department of Chemical Biology, Faculty of Science Palack\u00fd University  Olomouc Czech 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