{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T05:49:44Z","timestamp":1776491384671,"version":"3.51.2"},"reference-count":30,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T00:00:00Z","timestamp":1770249600000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2025M773818"],"award-info":[{"award-number":["2025M773818"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U24A20406"],"award-info":[{"award-number":["U24A20406"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bsppjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Molecular Plant Pathology"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Fhb1<\/jats:italic>\n                    is the most widely used locus for Fusarium head blight (FHB) resistance in wheat, yet the mechanistic basis of its candidate gene,\n                    <jats:italic>TaHRC<\/jats:italic>\n                    , remains elusive. Here, we demonstrate that the protein from the resistant allele TaHRC\u2010R localises to both the nucleus and cytoplasm, whereas the susceptible protein TaHRC\u2010S is confined to the nucleus. Remarkably, only TaHRC\u2010R triggered a reactive oxygen species (ROS) burst in planta, dependent on its extranuclear localisation. The N\u2010terminal 21 amino acids that distinguish TaHRC\u2010R from TaHRC\u2010S were essential for its nuclear export and ROS induction. Within the nucleus, TaHRC\u2010R formed heterodimers with TaHRC\u2010S via its N\u2010terminal 21 amino acids and central region, disrupting the formation of large, sparse TaHRC\u2010S condensates and converting them into numerous smaller assemblies. These results reveal a dual, spatially coordinated mechanism whereby TaHRC\u2010R promotes ROS production outside the nucleus while modulating nuclear condensate dynamics to counteract the susceptible allele. This compartmentalised functionality provides a molecular framework for\n                    <jats:italic>Fhb1<\/jats:italic>\n                    \u2010mediated resistance and illustrates a novel paradigm of subcellular specialisation in plant immunity.\n                  <\/jats:p>","DOI":"10.1111\/mpp.70218","type":"journal-article","created":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T12:36:21Z","timestamp":1770294981000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Compartmentalised Function of\n                    <scp>TaHRC<\/scp>\n                    \u2010R Orchestrates\n                    <scp>ROS<\/scp>\n                    Production and Nuclear Condensate Dynamics"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-9252-7097","authenticated-orcid":false,"given":"Yang","family":"Yang","sequence":"first","affiliation":[{"name":"Hainan Research Institute of Northwest A&amp;F University  Sanya China"},{"name":"State Key Laboratory for Crop Stress Resistance and High\u2010Efficiency Production College of Plant Protection, Northwest A&amp;F University  Yangling China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8997-069X","authenticated-orcid":false,"given":"Qingwen","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Crop Stress Resistance and High\u2010Efficiency Production College of Plant Protection, Northwest A&amp;F University  Yangling China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-2095-4562","authenticated-orcid":false,"given":"Xin","family":"Ou","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Crop Stress Resistance and High\u2010Efficiency Production College of Plant Protection, Northwest A&amp;F University  Yangling 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China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8139-662X","authenticated-orcid":false,"given":"Guanghui","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Crop Stress Resistance and High\u2010Efficiency Production College of Plant Protection, Northwest A&amp;F University  Yangling China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3415-8004","authenticated-orcid":false,"given":"Ming","family":"Xu","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Crop Stress Resistance and High\u2010Efficiency Production College of Plant Protection, Northwest A&amp;F University  Yangling China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-9045-8216","authenticated-orcid":false,"given":"Jie","family":"Liang","sequence":"additional","affiliation":[{"name":"Mianyang Academy of Agricultural 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