{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:16:20Z","timestamp":1787015780228,"version":"build-2736575974"},"reference-count":63,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,7,12]],"date-time":"2026-07-12T00:00:00Z","timestamp":1783814400000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2023YFD1400300"],"award-info":[{"award-number":["2023YFD1400300"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007834","name":"Natural Science Foundation of Ningbo Municipality","doi-asserted-by":"publisher","award":["2023J382"],"award-info":[{"award-number":["2023J382"]}],"id":[{"id":"10.13039\/100007834","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bsppjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Molecular Plant Pathology"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    As a transcriptional co\u2010factor of E2F, DP proteins are typically involved in the regulation of plant cell\u2010cycle\u2010related processes. However, whether DP proteins participate in transcriptional regulation associated with plant antiviral defence remains largely unclear. This study demonstrates that NbDPB, a DP family protein in\n                    <jats:italic>Nicotiana benthamiana<\/jats:italic>\n                    , positively regulates resistance to potato virus X (PVX) by functioning as a transcription factor. Knockout of\n                    <jats:italic>NbDPB<\/jats:italic>\n                    increased plant susceptibility to PVX, while its overexpression significantly suppressed viral accumulation. Furthermore, we identified that NbDPB binds to the promoter of\n                    <jats:italic>NbMYB<\/jats:italic>\n                    (a MYB transcription factor) and positively regulates its expression. Silencing\n                    <jats:italic>NbMYB<\/jats:italic>\n                    enhanced PVX infection, whereas exogenous application of jasmonic acid (JA) and salicylic acid (SA) partially rescued this phenotype. Hormone levels of JA and SA, as well as the expression levels of their marker genes, were significantly reduced in the silenced\n                    <jats:italic>NbMYB<\/jats:italic>\n                    plants. These findings suggest that the NbDPB\u2010NbMYB module mediates antiviral defence through the JA and SA signalling pathways. This study reveals a previously uncharacterized role of DP proteins in antiviral transcriptional regulation, indicating that they may play a crucial role in plant antiviral defence.\n                  <\/jats:p>","DOI":"10.1111\/mpp.70319","type":"journal-article","created":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T04:30:59Z","timestamp":1783917059000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The Transcription Factor\n                    <scp>DPB<\/scp>\n                    Confers Antiviral Defence Against Potato Virus X by Modulating\n                    <scp>MYB<\/scp>\n                    \u2010Dependent Signalling"],"prefix":"10.1111","volume":"27","author":[{"given":"Jingjing","family":"Shi","sequence":"first","affiliation":[{"name":"State Key Laboratory for Quality and Safety of Agro\u2010Products, Key Laboratory of Biotechnology in Plant Protection of MARA, Key Laboratory of Green Plant Protection of Zhejiang Province, Institute of Plant Virology Ningbo University  Ningbo China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yumei","family":"Zhao","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Quality and Safety of Agro\u2010Products, Key Laboratory of Biotechnology in Plant Protection of MARA, Key Laboratory of Green Plant Protection of Zhejiang Province, Institute of Plant Virology Ningbo University  Ningbo China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunyan","family":"Qi","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Quality and Safety of Agro\u2010Products, Key Laboratory of Biotechnology in Plant Protection of MARA, Key Laboratory of Green Plant Protection of Zhejiang Province, Institute of Plant Virology Ningbo University  Ningbo China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaoyao","family":"Jiang","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Quality and Safety of Agro\u2010Products, Key Laboratory of Biotechnology in Plant Protection of MARA, Key Laboratory of Green Plant Protection of Zhejiang Province, Institute of Plant Virology Ningbo University  Ningbo China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Yong","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Quality and Safety of Agro\u2010Products, Key Laboratory of Biotechnology in Plant Protection of MARA, Key Laboratory of Green Plant Protection of Zhejiang Province, Institute of Plant Virology Ningbo University  Ningbo China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingyun","family":"Lei","sequence":"additional","affiliation":[{"name":"Ministry of Agriculture Key Laboratory of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology Zhejiang University  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenhao","family":"Wang","sequence":"additional","affiliation":[{"name":"Luohe Academy of Agricultural Science  Luohe China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Liu","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Quality and Safety of Agro\u2010Products, Key Laboratory of Biotechnology in Plant Protection of MARA, Key Laboratory of Green Plant Protection of Zhejiang Province, Institute of Plant Virology Ningbo University  Ningbo China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaqian","family":"Liu","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Quality and Safety of Agro\u2010Products, Key Laboratory of Biotechnology in Plant Protection of MARA, Key Laboratory of Green Plant Protection of Zhejiang Province, Institute of Plant Virology Ningbo University  Ningbo China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0699-3117","authenticated-orcid":false,"given":"Tianye","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Quality and Safety of Agro\u2010Products, Key Laboratory of Biotechnology in Plant Protection of MARA, Key Laboratory of Green Plant Protection of Zhejiang Province, Institute of Plant Virology Ningbo University  Ningbo China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3849-4080","authenticated-orcid":false,"given":"Jianping","family":"Chen","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Quality and Safety of Agro\u2010Products, Key Laboratory of Biotechnology in Plant Protection of MARA, Key Laboratory of Green Plant Protection of Zhejiang Province, Institute of Plant Virology Ningbo University  Ningbo China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4456-7231","authenticated-orcid":false,"given":"Jian","family":"Yang","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Quality and Safety of Agro\u2010Products, Key Laboratory of Biotechnology in Plant Protection of MARA, Key Laboratory of Green Plant Protection of Zhejiang Province, Institute of Plant Virology Ningbo University  Ningbo China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianbo","family":"Liu","sequence":"additional","affiliation":[{"name":"Tobacco Research Institute of Hunan Province  Changsha Hunan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaili","family":"Zhong","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Quality and Safety of Agro\u2010Products, Key Laboratory of Biotechnology in Plant Protection of MARA, Key Laboratory of Green Plant Protection of Zhejiang Province, Institute of Plant Virology Ningbo University  Ningbo China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,12]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/genes11030343"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/jxb\/ern277"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.2174\/1389203717666160619185308"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.108.121038"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.4314\/biokem.v16i2.32579"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibs.2004.06.006"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-79910-5_5"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2004.09.037"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2017.10.019"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.16.00954"},{"key":"e_1_2_9_12_1","first-page":"739","article-title":"Distinct and Overlapping Roles for E2F Family Members in Transcription, Proliferation and Apoptosis","volume":"6","author":"DeGregori J.","year":"2006","journal-title":"Current Molecular Medicine"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1208612"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0019008"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tplants.2018.08.010"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/tpj.70400"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.110.080788"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-023-05259-2"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.0c06740"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2019.00822"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/mp\/ssu049"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00282746"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.107.110981"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2020.583153"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molp.2019.11.001"},{"key":"e_1_2_9_26_1","first-page":"575","article-title":"Hormone\u2013Virus Interaction in Carcinogenesis \u2013 a Clue to the Etiology of AIDS (Review)","volume":"3","author":"Kodama M.","year":"1993","journal-title":"International Journal of Oncology"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virusres.2014.07.012"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12870-021-02924-8"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep09682"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1080\/15592324.2015.1044192"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00122-022-04214-9"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/nph.18383"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-313X.2002.01394.x"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-313X.2004.02085.x"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/pbi.70246"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(00)02238-9"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.014167"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/mpp.12077"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.105.073783"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/27.1.29"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.108.064691"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.110.076067"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2021.652570"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1094\/PDIS-91-5-0609"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1101\/gr.080622.108"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-313X.2003.01662.x"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/27.17.3527"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.949802"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1094\/MPMI-23-4-0394"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1023\/B:BIOM.0000027708.27142.bc"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8137.2010.03183.x"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1369-5266(00)00199-0"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1111\/ppl.14257"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.152047199"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.107.113829"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1111\/nph.14569"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2014.10.005"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.3390\/plants14040518"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-022-00710-3"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jplph.2022.153680"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1111\/nph.19507"},{"key":"e_1_2_9_62_1","doi-asserted-by":"publisher","DOI":"10.3390\/plants9091246"},{"key":"e_1_2_9_63_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.25.14972"},{"key":"e_1_2_9_64_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1009242"}],"container-title":["Molecular Plant Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/bsppjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/mpp.70319","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bsppjournals.onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/mpp.70319","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bsppjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/mpp.70319","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T04:55:58Z","timestamp":1785214558000},"score":1,"resource":{"primary":{"URL":"https:\/\/bsppjournals.onlinelibrary.wiley.com\/doi\/10.1111\/mpp.70319"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":63,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1111\/mpp.70319"],"URL":"https:\/\/doi.org\/10.1111\/mpp.70319","archive":["Portico"],"relation":{},"ISSN":["1464-6722","1364-3703"],"issn-type":[{"value":"1464-6722","type":"print"},{"value":"1364-3703","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"2026-01-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-01","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70319"}}