{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T05:56:56Z","timestamp":1790575016664,"version":"4.1.0"},"reference-count":66,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:00:00Z","timestamp":1790208000000},"content-version":"vor","delay-in-days":23,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["RS\u20102024\u201000407104"],"award-info":[{"award-number":["RS\u20102024\u201000407104"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["RS\u20102025\u201016071113"],"award-info":[{"award-number":["RS\u20102025\u201016071113"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bsppjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Molecular Plant Pathology"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The nucleolus is a central hub for nuclear functions, including, but not limited to, ribosome biogenesis in mammals and budding yeast. However, how the nucleolus is regulated and contributes to fungal development and pathogenesis is poorly understood. Here we report that a JmjC domain\u2010containing histone demethylase MoJMJD2 is required for rDNA transcription and nucleolar integrity in the rice blast fungus,\n                    <jats:italic>Magnaporthe oryzae<\/jats:italic>\n                    .\n                    <jats:italic>MoJMJD2<\/jats:italic>\n                    generates two alternatively spliced isoforms with distinct subcellular localization patterns, suggesting coordinated roles in gene regulation in the nucleolus and nucleoplasm. Deletion of\n                    <jats:italic>MoJMJD2<\/jats:italic>\n                    rendered the fungus defective in hyphal growth, sporulation and pathogenicity. Notably, loss of\n                    <jats:italic>MoJMJD2<\/jats:italic>\n                    led to mislocalization of a nucleolar protein to the nucleoplasm and a dramatic reduction of cellular protein synthesis, suggesting the disruption of functional nucleolar structure. Taken together, these results indicate that nucleolar integrity and functions, which are under epigenetic control associated with MoJMJD2, are required for the development and pathogenicity of the rice blast fungus.\n                  <\/jats:p>","DOI":"10.1111\/mpp.70352","type":"journal-article","created":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T07:46:16Z","timestamp":1790235976000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Histone Demethylase\n                    <scp>JMJD2<\/scp>\n                    \u2010Dependent Regulation of\n                    <scp>rDNA<\/scp>\n                    Transcription and Integrity of Nucleolus Is Required for Fungal Development and Pathogenicity in the Rice Blast Fungus"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2090-4704","authenticated-orcid":false,"given":"Song Hee","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Biotechnology, College of Life and Applied Sciences Yeungnam University  Gyeongsan Gyeongbuk Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taehyeon","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, College of Life and Applied Sciences Yeungnam University  Gyeongsan Gyeongbuk Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1892-225X","authenticated-orcid":false,"given":"Joo Hyun","family":"Lee","sequence":"additional","affiliation":[{"name":"Plant Immunity Research Center Seoul National University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1179-4574","authenticated-orcid":false,"given":"Jiyeun","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Agricultural Biotechnology Seoul National University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8249-5283","authenticated-orcid":false,"given":"Ki\u2010Tae","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Agricultural Life Science Sunchon National University  Suncheon Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5080-7951","authenticated-orcid":false,"given":"Hokyoung","family":"Son","sequence":"additional","affiliation":[{"name":"Department of Agricultural Biotechnology Seoul National University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0617-4007","authenticated-orcid":false,"given":"Junhyun","family":"Jeon","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, College of Life and Applied Sciences Yeungnam University  Gyeongsan Gyeongbuk Republic of Korea"},{"name":"Phytobiome Engineering Research Laboratory Yeungnam University  Gyeongsan Gyeongbuk Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,24]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-12-4300"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm2184"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2010.09.024"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-024-05941-z"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/yea.3007"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.5423\/PPJ.2009.25.1.108"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1128\/mbio.01844-23"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/database\/bav052"},{"key":"e_1_2_9_10_1","first-page":"580","article-title":"Septin\u2010Mediated Plant Cell Invasion by the Rice Blast Fungus, Magnaporthe oryzae","volume":"312","author":"Dagdas Y. 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