{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T04:37:41Z","timestamp":1792730261694,"version":"4.5.0"},"reference-count":39,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T00:00:00Z","timestamp":1792627200000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["bsppjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Molecular Plant Pathology"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Panax notoginseng<\/jats:italic>\n                    is an edible traditional medicinal plant, but it is highly susceptible to Panax notoginseng virus Y (PnVY). This study revealed that salicylic acid (SA) treatment decreases this susceptibility. The underlying molecular mechanism was elucidated by integrating physiological, multi\u2010omics and genetic approaches. SA application alleviated PnVY\u2010induced photosynthetic inhibition and activated antioxidant enzymes, thereby decreasing reactive oxygen species levels and maintaining redox homeostasis. Upon PnVY inoculation, SA triggered a range of defence responses. The exogenous application of SA promoted the accumulation of phenylpropanoids, alkaloids and flavonoids, which was consistent with the upregulated expression of phenylpropanoid biosynthesis\u2010related genes. Transcriptional regulatory network analysis revealed that the ethylene\u2010responsive transcription factor PnERF120 may positively regulate the biosynthesis of phenolic acids including SA. Overexpressing\n                    <jats:italic>PnERF120<\/jats:italic>\n                    enhanced the resistance of\n                    <jats:italic>P. notoginseng<\/jats:italic>\n                    to PnVY, activated SA biosynthesis and signal transduction pathway, upregulated the RNA\u2010silencing\u2010related genes and improved phenolic acid accumulation. However, silencing\n                    <jats:italic>PnERF120<\/jats:italic>\n                    in\n                    <jats:italic>P. notoginseng<\/jats:italic>\n                    had the opposite effect. Additionally, yeast one\u2010hybrid and dual\u2010luciferase assays indicated that PnERF120 binds to the promoter of\n                    <jats:italic>PnPAL1<\/jats:italic>\n                    and activates\n                    <jats:italic>PnPAL1<\/jats:italic>\n                    expression. In conclusion,\n                    <jats:italic>PnERF120<\/jats:italic>\n                    positively regulates defence against PnVY infection by modulating SA biosynthesis and the SA signalling pathway.\n                  <\/jats:p>","DOI":"10.1111\/mpp.70360","type":"journal-article","created":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T03:47:36Z","timestamp":1792727256000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Multi\u2010Omics Analysis Uncovers the Salicylic Acid and Ethylene\u2010Responsive Transcription Factor\u2010Mediated Defence Mechanism of\n                    <scp>\n                      <i>Panax notoginseng<\/i>\n                    <\/scp>\n                    to Panax notoginseng Virus Y"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1564-520X","authenticated-orcid":false,"given":"Wenyun","family":"Li","sequence":"first","affiliation":[{"name":"Faculty of Life Science and Technology Kunming University of Science and Technology  Kunming Yunnan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongchao","family":"He","sequence":"additional","affiliation":[{"name":"Faculty of Life Science and Technology Kunming University of Science and Technology  Kunming Yunnan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Qu","sequence":"additional","affiliation":[{"name":"Faculty of Life Science and Technology Kunming University of Science and Technology  Kunming Yunnan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2720-6303","authenticated-orcid":false,"given":"Diqiu","family":"Liu","sequence":"additional","affiliation":[{"name":"Faculty of Life Science and Technology Kunming University of Science and Technology  Kunming Yunnan China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,22]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u2010313X.2006.02861.x"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20102538"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.plaphy.2014.01.016"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.plaphy.2023.108038"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jare.2018.01.001"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/plants13172509"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev\u2010phyto\u2010121323\u2010021434"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.2018.1962"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tplants.2023.10.014"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010023\u201006533\u20103"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/ps.70128"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1902771116"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2302069120"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/nph.70180"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.111.178012"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/mpp.70066"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2020.603518"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1094\/MPMI\u201009\u201010\u20100224"},{"key":"e_1_2_9_20_1","volume-title":"Physiological and Molecular Plant Pathology","author":"Li J. 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