{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T22:47:37Z","timestamp":1783118857774,"version":"3.54.6"},"reference-count":37,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,12,2]],"date-time":"2022-12-02T00:00:00Z","timestamp":1669939200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["resjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Medical Vet Entomology"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Lutzomyia longipalpis<\/jats:italic>\n                    is known as one of the primary insect vectors of visceral leishmaniasis\n                    <jats:italic>.<\/jats:italic>\n                    For such ectothermic organisms, the ambient temperature is a critical life factor. However, the impact of temperature has been ignored in many induced\u2010stress situations of the vector life. Therefore, this study explored the interaction of\n                    <jats:italic>Lu. longipalpis<\/jats:italic>\n                    with temperature by evaluating its behaviour across a thermal gradient, thermographic recordings during blood\u2010feeding on mice, and the gene expression of heat shock proteins (HSP) when insects were exposed to extreme temperature or infected. The results showed that 72\u2009h after blood ingestion,\n                    <jats:italic>Lu. longipalpis<\/jats:italic>\n                    became less active and preferred relatively low temperatures. However, at later stages of blood digestion, females increased their activity and remained at higher temperatures. Real\u2010time imaging showed that the body temperature of females can adjust rapidly to the host and remain constant until the end of blood\u2010feeding. Insects also increased the expression of HSP90(83) during blood\u2010feeding. Our findings suggest that\n                    <jats:italic>Lu. longipalpis<\/jats:italic>\n                    interacts with temperature by using its behaviour to avoid temperature\u2010induced physiological damage during the gonotrophic cycle. However, the expression of certain HSP might be triggered to mitigate thermal stress in situations where a behavioural response is not the best option.\n                  <\/jats:p>","DOI":"10.1111\/mve.12626","type":"journal-article","created":{"date-parts":[[2022,12,2]],"date-time":"2022-12-02T08:22:28Z","timestamp":1669969348000},"page":"238-251","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Response to thermal and infection stresses in an American vector of visceral leishmaniasis"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6882-3220","authenticated-orcid":false,"given":"Kelsilandia Aguiar","family":"Martins","sequence":"first","affiliation":[{"name":"Faculty of Health and Medicine, Division of Biomedical and Life Sciences Lancaster University  Lancaster UK"},{"name":"Instituto de Ci\u00eancias Biol\u00f3gicas Universidade Federal de Minas Gerais  Belo Horizonte Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline S.","family":"Morais","sequence":"additional","affiliation":[{"name":"Faculty of Health and Medicine, Division of Biomedical and Life Sciences Lancaster University  Lancaster UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan J.","family":"Broughton","sequence":"additional","affiliation":[{"name":"Faculty of Health and Medicine, Division of Biomedical and Life Sciences Lancaster University  Lancaster UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio R.","family":"Lazzari","sequence":"additional","affiliation":[{"name":"Institut de Recherche sur la Biologie de l'Insecte UMR 7261 CNRS\u2010Universit\u00e9 de Tours  Tours France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul A.","family":"Bates","sequence":"additional","affiliation":[{"name":"Faculty of Health and Medicine, Division of Biomedical and Life Sciences Lancaster University  Lancaster UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcos H.","family":"Pereira","sequence":"additional","affiliation":[{"name":"Instituto de Ci\u00eancias Biol\u00f3gicas Universidade Federal de Minas Gerais  Belo Horizonte Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rod J.","family":"Dillon","sequence":"additional","affiliation":[{"name":"Faculty of Health and Medicine, Division of Biomedical and Life Sciences Lancaster University  Lancaster UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,12,2]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2486.2002.00451.x"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1105195108"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-8-72"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13071-018-3019-x"},{"key":"e_1_2_9_6_1","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1111\/j.1365-2435.2007.01341.x","article-title":"Scaling of body temperature in mammals and birds","volume":"22","author":"Clarke A.","year":"2007","journal-title":"Functional Ecology"},{"key":"e_1_2_9_7_1","first-page":"225","article-title":"Observa\u00e7\u00f5es sobre abrigos e criadouros de fleb\u00f3tomos no noroeste do Estado do Cear\u00e1","volume":"9","author":"Deane L.M.","year":"1957","journal-title":"Revista Brasileira de Malariologia e Doen\u00e7as\u2009Tropicais"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/jmedent\/34.6.719"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7519(03)00142-5"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.7705\/biomedica.v20i3.1060"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.260.5111.1155"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13071-018-3278-6"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1590\/0037-8682-0415-2015"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1603\/ME13053"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1442-9993.2001.01135.x"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.26107"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2011.11.029"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02762005000800001"},{"key":"e_1_2_9_19_1","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1007\/978-94-011-7953-9","volume-title":"Biology of blood\u2010sucking insects","author":"Lehane M.","year":"1991"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2019.01.301"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1006\/meth.2001.1262"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1242\/jeb.047415"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/jmedent\/21.6.681"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2005.11.031"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/jmedent\/20.5.568"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/2472508"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1242\/jeb.48.3.455"},{"issue":"7","key":"e_1_2_9_28_1","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0006684","article-title":"Ecological niche modelling and predicted geographic distribution of Lutzomyia cruzi, vector of Leishmania infantum in South America","volume":"12","author":"Oliveira E.F.","year":"2018","journal-title":"PLoS Neglected Tropical Diseases"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ibmb.2016.07.011"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2003.11.177"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1186\/1756-3305-7-278"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.108.065318"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41564-018-0125-7"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1316145111"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0169-5347(03)00069-7"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/1462-2920.14347"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2311.1983.tb00524.x"},{"key":"e_1_2_9_38_1","first-page":"93","article-title":"Expression of heat shock protein genes in insect stress responses","volume":"9","author":"Zhao L.","year":"2012","journal-title":"ISJ"}],"container-title":["Medical and Veterinary Entomology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/mve.12626","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/mve.12626","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/resjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/mve.12626","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T15:53:51Z","timestamp":1762271631000},"score":1,"resource":{"primary":{"URL":"https:\/\/resjournals.onlinelibrary.wiley.com\/doi\/10.1111\/mve.12626"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,2]]},"references-count":37,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["10.1111\/mve.12626"],"URL":"https:\/\/doi.org\/10.1111\/mve.12626","archive":["Portico"],"relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2020.11.23.373100","asserted-by":"object"}]},"ISSN":["0269-283X","1365-2915"],"issn-type":[{"value":"0269-283X","type":"print"},{"value":"1365-2915","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,2]]},"assertion":[{"value":"2021-11-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-10-31","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-12-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}