{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T15:50:38Z","timestamp":1788537038337,"version":"build-2803163510"},"reference-count":51,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T00:00:00Z","timestamp":1710288000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["resjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Medical Vet Entomology"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Aedes albopictus<\/jats:italic>\n                    is highly prevalent in the northern part of West Bengal and is considered to be responsible for the recent dengue outbreaks in this region. Control of this vector is largely relied on the use of synthetic pyrethroids, which can lead to the development of resistance. In the present study, larvae of three wild\n                    <jats:italic>Ae. albopictus<\/jats:italic>\n                    populations from the dengue\u2010endemic regions were screened for deltamethrin resistance, and the role of cytochrome P450 monooxygenases (CYPs) was investigated in deltamethrin exposed and unexposed larvae. Two populations were incipient resistant, and one population was completely resistant against deltamethrin. Monooxygenase titration assay revealed the involvement of CYPs in deltamethrin resistance along with an induction effect of deltamethrin exposure. Gene expression studies revealed differential expression of five CYP6 family genes,\n                    <jats:italic>CYP6A8<\/jats:italic>\n                    ,\n                    <jats:italic>CYP6P12<\/jats:italic>\n                    ,\n                    <jats:italic>CYP6A14<\/jats:italic>\n                    ,\n                    <jats:italic>CYP6N3<\/jats:italic>\n                    and\n                    <jats:italic>CYP6N6<\/jats:italic>\n                    , with high constitutive expression of\n                    <jats:italic>CYP6A8<\/jats:italic>\n                    and\n                    <jats:italic>CYP6P12<\/jats:italic>\n                    in all the populations before and after deltamethrin exposure. From these findings, it was evident that CYPs play an important role in the development of deltamethrin resistance in the\n                    <jats:italic>Ae. albopictus<\/jats:italic>\n                    populations in this region.\n                  <\/jats:p>","DOI":"10.1111\/mve.12713","type":"journal-article","created":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T17:24:05Z","timestamp":1710350645000},"page":"269-279","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Effects of deltamethrin exposure on the cytochrome\n                    <scp>P450<\/scp>\n                    monooxygenases of\n                    <i>Aedes albopictus<\/i>\n                    (\n                    <scp>Skuse<\/scp>\n                    ) larvae from a dengue\u2010endemic region of northern part of\n                    <scp>West Bengal, India<\/scp>"],"prefix":"10.1111","volume":"38","author":[{"given":"Prapti","family":"Das","sequence":"first","affiliation":[{"name":"Insect Biochemistry and Molecular Biology Laboratory, Department of Zoology University of North Bengal  Siliguri India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Subhajit","family":"Das","sequence":"additional","affiliation":[{"name":"Insect Biochemistry and Molecular Biology Laboratory, Department of Zoology University of North Bengal  Siliguri India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhirup","family":"Saha","sequence":"additional","affiliation":[{"name":"Insect Biochemistry and Molecular Biology Laboratory, Department of Zoology University of North Bengal  Siliguri India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-3799-7508","authenticated-orcid":false,"given":"Debayan","family":"Raha","sequence":"additional","affiliation":[{"name":"Insect 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