{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T01:02:31Z","timestamp":1790384551223,"version":"4.1.0"},"reference-count":30,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T00:00:00Z","timestamp":1767657600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T00:00:00Z","timestamp":1767657600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["resjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Medical Vet Entomology"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Heavy metal exposure represents a substantial health risk to humans and other animals, in some cases leading to death. However, detecting these metals in decaying corpses can pose a considerable challenge. In such situations, the eventual presence of necrophagous insects feeding on the remains may serve as a valuable tool for detecting and measuring these toxic substances. Nonetheless, heavy metals might affect insect development and survival rates. This study explored the effects of increasing concentrations of arsenic, mercury, cadmium and lead compounds on the survival and development rate of\n                    <jats:italic>Calliphora vicina<\/jats:italic>\n                    (Robineau Desvoidy, 1830) (Diptera: Calliphoridae) larvae. Additionally, the research investigated the possibility of tracing these metals in the developed larvae and whether bioaccumulation occurred. The larvae were reared in a dog food matrix infused with varying concentrations of these heavy metal compounds, ranging from 0.0 (control) to 60\u2009mg\/kg. The results showed that all tested metals increased mortality rates in a non\u2010linear dose\u2010dependent manner. Higher concentrations of each metal limited larval growth, as evidenced by lower length and weight than the control group. This growth inhibition could lead to inaccurate post\u2010mortem estimations based on entomological evidence collected in heavily contaminated substrates. All metals were successfully detected in the larvae; however, bioaccumulation was only confirmed for cadmium at low concentrations. Therefore,\n                    <jats:italic>C. vicina<\/jats:italic>\n                    larvae can serve as a valuable toxicological indicator for these elements, especially when larvae are found in the corpses of individuals chronically exposed to the assessed heavy metals.\n                  <\/jats:p>","DOI":"10.1111\/mve.70047","type":"journal-article","created":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T10:02:33Z","timestamp":1767693753000},"page":"386-395","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Detection of arsenic, mercury, cadmium and lead compounds in\n                    <scp>\n                      <i>Calliphora vicina<\/i>\n                    <\/scp>\n                    (Diptera: Calliphoridae) larvae and their potential impact on larval development"],"prefix":"10.1111","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-3936-2779","authenticated-orcid":false,"given":"Ana Catarina","family":"Fialho","sequence":"first","affiliation":[{"name":"Egas Moniz School of Health and Science  Almada Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasco","family":"Branco","sequence":"additional","affiliation":[{"name":"Research Institute for Medicines (iMed.ULisboa); Faculty of Pharmacy of University of Lisbon  Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8229-1707","authenticated-orcid":false,"given":"Edite","family":"Oliveira\u2010Torres","sequence":"additional","affiliation":[{"name":"Egas Moniz Center for Interdisciplinary Research (CiiEM); Egas Moniz School of Health &amp; Science  Almada Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Research Institute for Medicines (iMed.ULisboa); Faculty of Pharmacy of University of Lisbon  Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Quintas","sequence":"additional","affiliation":[{"name":"Egas Moniz Center for Interdisciplinary Research (CiiEM); Egas Moniz School of Health &amp; Science  Almada Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Fam\u00edlia","sequence":"additional","affiliation":[{"name":"Egas Moniz Center for Interdisciplinary Research (CiiEM); Egas Moniz School of Health &amp; Science  Almada Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo","family":"Mascarenhas","sequence":"additional","affiliation":[{"name":"Egas Moniz Center for Interdisciplinary Research (CiiEM); Egas Moniz School of Health &amp; Science  Almada Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,1,6]]},"reference":[{"key":"e_1_2_11_2_1","volume-title":"Quest Graph\u2122 LD50 Calculator","author":"AAT Bioquest, Inc","year":"2024"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12024-010-9209-2"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/toxics11040327"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2021.643972"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00216021-03257-z"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1201\/NOE0849392153"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-444-62627-1.00011-1"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.98106s1357"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.taap.2004.06.023"},{"key":"e_1_2_11_11_1","doi-asserted-by":"crossref","unstructured":"Donovan S.E. Hall M.J.R. Turner B.D.&Moncrieff C.B.(2006)Medical and veterinary entomology 20 106\u2013114. Available from:https:\/\/doi.org\/10.1111\/j.1365-2915.2006.00600.x","DOI":"10.1111\/j.1365-2915.2006.00600.x"},{"key":"e_1_2_11_12_1","unstructured":"Fialho A.C.(2025)Experimental data on the effects of heavy metal compounds on the development survival and bioaccumulation patterns inCalliphora vicinalarvae. [dataset] Dryadhttps:\/\/doi.org\/10.5061\/dryad.6m905qgdj"},{"issue":"2","key":"e_1_2_11_13_1","first-page":"4","article-title":"Metal poisoning: threat and management","volume":"2","author":"Flora S.J.S.","year":"2009","journal-title":"Al Ameen Journal of Medical Sciences"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004140000181"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.forsciint.2010.12.015"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/0013-9351(78)90073-7"},{"key":"e_1_2_11_17_1","unstructured":"Kaur B.(2016)Detection of some heavy metals from maggots and their effect on the development ofChrysomya megacephala(Fab.) (Diptera Calliphoridae) [PhD thesis]. Punjabi University."},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/jme\/tjac134"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/jme\/tjab123"},{"key":"e_1_2_11_20_1","volume-title":"StatPearls [Internet]","author":"Kuivenhoven M.","year":"2025"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.3389\/fchem.2020.586067"},{"key":"e_1_2_11_22_1","first-page":"34","article-title":"The fate of mercury in Sarcosaprophagous flies and in insects eating them report","volume":"11","author":"Nuorteva P.","year":"1982","journal-title":"Ambio"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1109\/ISBEIA.2012.6422946"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.26234"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/bf02332323"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1515\/foecol-2017-0004"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/0269-7491(93)90026-K"},{"key":"e_1_2_11_28_1","first-page":"43","volume-title":"Current concepts in forensic entomology","author":"Szpila K.","year":"2010"},{"key":"e_1_2_11_29_1","first-page":"77","volume-title":"Forensic entomology: an introduction","author":"Szpila K.","year":"2012"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-7643-8340-4_6"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1080\/00498254.2021.1922781"}],"container-title":["Medical and Veterinary Entomology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/resjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/mve.70047","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/resjournals.onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/mve.70047","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/resjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/mve.70047","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T11:12:30Z","timestamp":1778065950000},"score":1,"resource":{"primary":{"URL":"https:\/\/resjournals.onlinelibrary.wiley.com\/doi\/10.1111\/mve.70047"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,6]]},"references-count":30,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10.1111\/mve.70047"],"URL":"https:\/\/doi.org\/10.1111\/mve.70047","archive":["Portico"],"relation":{},"ISSN":["0269-283X","1365-2915"],"issn-type":[{"value":"0269-283X","type":"print"},{"value":"1365-2915","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,6]]},"assertion":[{"value":"2025-07-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}