{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T13:42:01Z","timestamp":1791121321801,"version":"4.1.0"},"reference-count":17,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2013,5]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>A number of herbal products with anti\u2010inflammatory, antiseptic and antimycotic properties are available for dermatological usage. The successful treatment of 13 sheep affected by ringworm due to <jats:italic>Trichophyton mentagrophytes<\/jats:italic> with a mixture consisting of essential oils (EOs) of <jats:italic>Thymus serpillum<\/jats:italic> 2%, <jats:italic>Origanum vulgare<\/jats:italic> 5% and <jats:italic>Rosmarinus officinalis<\/jats:italic> 5% in sweet almond (<jats:italic>Prunus dulcis<\/jats:italic>) oil. The effectiveness of EOs and of the major components of the mixture (thymol, carvacrol, 1,8 cineole, \u03b1\u2010pinene, p\u2010cymene, \u03b3\u2010terpinene) against the fungal clinical isolate was evaluated by a microdilution test. Thirteen animals were topically administered with the mixture twice daily for 15\u2003days. The other sheep were administered with a conventional treatment (seven animals) or left untreated (two animals). Minimum inhibitory concentration (MIC) values were 0.1% for <jats:italic>T. serpillum<\/jats:italic>, 0.5% for <jats:italic>O. vulgare<\/jats:italic>, 2.5% for <jats:italic>I. verum<\/jats:italic> and 5% for both <jats:italic>R. officinalis<\/jats:italic> and <jats:italic>C. limon.<\/jats:italic> Thymol and carvacrol showed MICs of 0.125% and 0.0625%. A clinical and aetiological cure was obtained at the end of each treatment regimen in only the treated animals. Specific antimycotic drugs licenced for food\u2010producing sheep are not available within the European Community. The mixture tested here appeared to be a versatile tool for limiting fungal growth.<\/jats:p>","DOI":"10.1111\/myc.12034","type":"journal-article","created":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T16:42:04Z","timestamp":1359736924000},"page":"333-337","source":"Crossref","is-referenced-by-count":23,"title":["A herbal antifungal formulation of <i>Thymus serpillum<\/i>, <i>Origanum vulgare<\/i> and <i>Rosmarinus officinalis<\/i> for treating ovine dermatophytosis due to <i>Trichophyton mentagrophytes<\/i>"],"prefix":"10.1111","volume":"56","author":[{"given":"Linda","family":"Mugnaini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simona","family":"Nardoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luisa","family":"Pistelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Leonardi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorella","family":"Giuliotti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria N.","family":"Benvenuti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Pisseri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Mancianti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,2]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2007.09.106"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2008.12.018"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2011.07.005"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2010.04.005"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1080\/02681219480000791"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11046-008-9102-7"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.2174\/1874437001004010010"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2885.2003.00457.x"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.46443-0"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.036988-0"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1021\/jf062610"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.1988.tb04436.x"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.989"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mycmed.2009.12.002"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1080\/03639040802130053"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10600-008-9162-4"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mycmed.2012.04.003"}],"container-title":["Mycoses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fmyc.12034","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/myc.12034","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T19:33:06Z","timestamp":1698694386000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/myc.12034"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2]]},"references-count":17,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,5]]}},"alternative-id":["10.1111\/myc.12034"],"URL":"https:\/\/doi.org\/10.1111\/myc.12034","archive":["Portico"],"relation":{},"ISSN":["0933-7407","1439-0507"],"issn-type":[{"value":"0933-7407","type":"print"},{"value":"1439-0507","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,2]]}}}