{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T02:16:59Z","timestamp":1791166619223,"version":"4.1.0"},"reference-count":23,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,4,8]],"date-time":"2013-04-08T00:00:00Z","timestamp":1365379200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2013,9]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Invasive aspergillosis (<jats:styled-content style=\"fixed-case\">IA<\/jats:styled-content>) seems to be an emerging condition in intensive care units (<jats:styled-content style=\"fixed-case\">ICU<\/jats:styled-content>s). However, little attention has been given to the role of environmental factors that could increase the risk for <jats:styled-content style=\"fixed-case\">IA<\/jats:styled-content> in the <jats:styled-content style=\"fixed-case\">ICU<\/jats:styled-content>. The objective of this study was to determine the concentration of airborne fungi in three Brazilian <jats:styled-content style=\"fixed-case\">ICU<\/jats:styled-content>s, in an attempt to correlate fungal burden with the frequency of <jats:italic>Aspergillus<\/jats:italic> spp isolation from clinical samples of patients hospitalised in these units. During a 1\u2010year period we quantitatively evaluated the presence of fungi in the air of three <jats:styled-content style=\"fixed-case\">ICU<\/jats:styled-content>s in Porto Alegre, Brazil. The quantity of fungi was correlated with environmental factors. Only one of the <jats:styled-content style=\"fixed-case\">ICU<\/jats:styled-content>s studied showed equal concentrations of <jats:italic>Aspergillus<\/jats:italic> conidia in the indoor air, in comparison with the outdoor environment. All cases of <jats:italic>Aspergillus<\/jats:italic> colonisation and <jats:styled-content style=\"fixed-case\">IA<\/jats:styled-content> cases observed during the study occurred in that particular <jats:styled-content style=\"fixed-case\">ICU<\/jats:styled-content>. Environmental factors have a direct influence on fungal spore concentration in the air in <jats:styled-content style=\"fixed-case\">ICU<\/jats:styled-content>s, as well as air filtration systems in air conditioners. Fungal contamination of the indoor air may influence the frequency of <jats:styled-content style=\"fixed-case\">AI<\/jats:styled-content> in <jats:styled-content style=\"fixed-case\">ICU<\/jats:styled-content> patients.<\/jats:p>","DOI":"10.1111\/myc.12070","type":"journal-article","created":{"date-parts":[[2013,4,9]],"date-time":"2013-04-09T03:46:54Z","timestamp":1365479214000},"page":"527-531","source":"Crossref","is-referenced-by-count":15,"title":["The indoor air as a potential determinant of the frequency of invasive aspergillosis in the intensive care"],"prefix":"10.1111","volume":"56","author":[{"given":"Cristiane","family":"Boff","sequence":"first","affiliation":[{"name":"Universidade Federal do Rio Grande do Sul Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara C. D. A.","family":"Zoppas","sequence":"additional","affiliation":[{"name":"Universidade de Caxias do Sul Caxias do Sul Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9rio R.","family":"Aquino","sequence":"additional","affiliation":[{"name":"Hospital de Cl\u00ednicas de Porto Alegre Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N\u00e1dia M.","family":"Kuplich","sequence":"additional","affiliation":[{"name":"Hospital de Cl\u00ednicas de Porto Alegre Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diogo","family":"Miron","sequence":"additional","affiliation":[{"name":"Universidade de Caxias do Sul Caxias do Sul Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro C.","family":"Pasqualotto","sequence":"additional","affiliation":[{"name":"Universidade Federal do Rio Grande do Sul Porto Alegre Brazil"},{"name":"Santa Casa Complexo Hospitalar Porto Alegre Brazil"},{"name":"Universidade Federal de Ci\u00eancias da Sa\u00fade de Porto Alegre Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,4,8]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1086\/518852"},{"key":"e_1_2_5_3_1","first-page":"810","article-title":"Pulmonary aspergillosis in patients with chronic obstrutive pulmonary disease: incidence, risk factors, and outcome","volume":"16","author":"Guinea J","year":"2009","journal-title":"Clin Microbiol Infect"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/cc4823"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200401-093OC"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-003-2008-4"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/cc3488"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1086\/505870"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200704-606OC"},{"key":"e_1_2_5_10_1","first-page":"1","volume-title":"Particulate Air Filters for General Ventilation. 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