{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T13:55:01Z","timestamp":1773323701775,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,7,8]],"date-time":"2013-07-08T00:00:00Z","timestamp":1373241600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mycoses"],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>The Ustilaginomycetous basidiomycete yeast, <jats:italic><jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>seudozyma aphidis<\/jats:italic> has recently been implicated in potentially fatal disorders ranging from subcutaneous mycoses to disseminated infections. Till date a solitary case of <jats:italic><jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>.\u00a0aphidis<\/jats:italic> fungaemia in a paediatric patient has been reported. We present a case of fungaemia due to <jats:italic><jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>.\u00a0aphidis<\/jats:italic> in a rhesus factor\u2010isoimmunised, low\u2010birth\u2010weight neonate. The isolate was identified by sequencing the D1\/D2 domain of the LSU region. Antifungal susceptibility of the isolate revealed susceptibility to amphotericin B, voriconazole, itraconazole, isavuconazole and posaconazole. It had high minimum inhibitory concentrations of fluconazole and was resistant to flucytosine and echinocandins. Consequently, the patient was successfully treated with intravenous amphotericin B. Although the source of infection could not be traced, as the neonate developed fungaemia on the first day of life, it could possibly be from the maternal urogenital tract or intrahospital transmission. A review of previously published cases revealed that risk factors for invasive <jats:italic><jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>seudozyma<\/jats:italic> spp. infections were similar to those previously reported for non\u2010<jats:italic>albicans <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>andida<\/jats:italic> spp. <jats:italic><jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>seudozyma<\/jats:italic> species are underreported due to the difficulty of identifying this rare yeast pathogen by commercial identification systems. Considering that <jats:italic><jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>seudozyma<\/jats:italic> spp. cause invasive fungal infections globally and are resistant to flucytosine, fluconazole and echinocandins, this pathogen assumes a greater clinical significance.<\/jats:p>","DOI":"10.1111\/myc.12098","type":"journal-article","created":{"date-parts":[[2013,7,9]],"date-time":"2013-07-09T04:55:46Z","timestamp":1373345746000},"page":"64-68","source":"Crossref","is-referenced-by-count":28,"title":["First neonatal case of fungaemia due to <i><scp>P<\/scp>seudozyma aphidis<\/i> and a global literature review"],"prefix":"10.1111","volume":"57","author":[{"given":"Anupam","family":"Prakash","sequence":"first","affiliation":[{"name":"Departments of Medical Mycology Vallabhbhai Patel Chest Institute University of Delhi Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandeep","family":"Wankhede","sequence":"additional","affiliation":[{"name":"Departments of Medical Mycology Vallabhbhai Patel Chest Institute University of Delhi Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pradeep K.","family":"Singh","sequence":"additional","affiliation":[{"name":"Departments of Medical Mycology Vallabhbhai Patel Chest Institute University of Delhi Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kshitij","family":"Agarwal","sequence":"additional","affiliation":[{"name":"Pulmonary Medicine Vallabhbhai Patel Chest Institute University of Delhi Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shallu","family":"Kathuria","sequence":"additional","affiliation":[{"name":"Departments of Medical Mycology Vallabhbhai Patel Chest Institute University of Delhi Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharmila","family":"Sengupta","sequence":"additional","affiliation":[{"name":"Department of Microbiology BLK Super Speciality Hospital New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Purabi","family":"Barman","sequence":"additional","affiliation":[{"name":"Department of Microbiology BLK Super Speciality Hospital New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacques F.","family":"Meis","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology Radboud University Nijmegen Medical Centre Nijmegen The Netherlands"},{"name":"Department of Medical Microbiology and Infectious Diseases Canisius\u2010Wilhelmina Hospital Nijmegen The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anuradha","family":"Chowdhary","sequence":"additional","affiliation":[{"name":"Departments of Medical Mycology Vallabhbhai Patel Chest Institute University of Delhi Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,7,8]]},"reference":[{"key":"e_1_2_8_2_1","volume-title":"The Yeasts: A Taxonomic Study","author":"Kurtzman CP","year":"2011"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1348-0421.2003.tb03385.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.47563-0"},{"key":"e_1_2_8_5_1","first-page":"315","volume-title":"PCR Protocols: A Guide to Methods and Applications","author":"White TJ","year":"1990"},{"key":"e_1_2_8_6_1","volume-title":"Reference Method for Broth Dilution Antifungal Susceptibility Testing of Yeasts","author":"Clinical and Laboratory Standards Institute","year":"2008"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1567-1364.2007.00251.x"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.carres.2008.08.034"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1263\/jbb.105.493"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiosc.2011.04.008"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03175125"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1139\/w04-073"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.3343\/kjlm.2010.30.3.284"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2010.04814.x"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2012.09.010"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-5-22"}],"container-title":["Mycoses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fmyc.12098","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/myc.12098","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T15:35:41Z","timestamp":1696260941000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/myc.12098"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,8]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,1]]}},"alternative-id":["10.1111\/myc.12098"],"URL":"https:\/\/doi.org\/10.1111\/myc.12098","archive":["Portico"],"relation":{},"ISSN":["0933-7407","1439-0507"],"issn-type":[{"value":"0933-7407","type":"print"},{"value":"1439-0507","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7,8]]}}}