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Voriconazole was administered at doses of 20 or 40\u00a0mg\u00a0kg<jats:sup>\u22121<\/jats:sup> per day by gavage. The drug showed some efficacy, especially at 40\u00a0mg\u00a0kg<jats:sup>\u22121<\/jats:sup> per day, in prolonging the survival and reducing fungal load in spleen and liver in mice infected with <jats:italic>S. schenckii<\/jats:italic>, whereas in animals infected with S<jats:italic>. brasiliensis<\/jats:italic> the drug did not work.<\/jats:p>","DOI":"10.1111\/myc.12112","type":"journal-article","created":{"date-parts":[[2013,7,24]],"date-time":"2013-07-24T13:22:11Z","timestamp":1374672131000},"page":"121-124","source":"Crossref","is-referenced-by-count":29,"title":["Modest efficacy of voriconazole against murine infections by <i>Sporothrix schenckii<\/i> and lack of efficacy against <i>Sporothrix brasiliensis<\/i>"],"prefix":"10.1111","volume":"57","author":[{"given":"Fabiola","family":"Fern\u00e1ndez\u2010Silva","sequence":"first","affiliation":[{"name":"Unitat d\u2032Anatomia Patol\u00f3gica Facultat de Medicina i Ci\u00e8ncies de la Salut IISPV Universitat Rovira i Virgili Reus 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